Abstract: A bone density estimating method, comprising: acquiring, by an MR scanning device, a magnetic resonance, MR, sequence of a body portion, wherein the MR sequence comprises quantitative information of the body portion; generating, by a processing circuit, an MR image of the body portion based on the MR sequence, wherein each voxel of the MR image represents a volume of the body portion; identifying, by the processing circuit, a part of the MR image representing a bone portion of the body portion; for a voxel of the identified part of the MR image, estimating a bone density of a volume of the bone portion represented by the voxel, based on a quantitative value of the voxel. The quantitative information of the body portion comprises a proton density.

Abstract: A method of quantifying lesion evolution, comprising: acquiring, by an MR scanning device, a first magnetic resonance, MR, sequence of a portion of a body comprising quantitative information of the portion; generating, by a processing circuit, a first MR image representing the portion, based on the first MR sequence, wherein each voxel of the first MR image represents a corresponding volume of the portion; and for a voxel of a first region of interest of the first MR image, determining a lesion evolution value indicating a status of lesion evolution, based on quantitative values of the voxel and a lesion evolution model; wherein the lesion evolution model comprises at least two sets of quantitative values comprising a first set of quantitative values representing the portion of an initial status of lesion evolution, and a second set of quantitative values representing the portion of a final status of lesion evolution.

Abstract: A bone density estimating method, comprising: acquiring, by an MR scanning device, a magnetic resonance, MR, sequence of a body portion, wherein the MR sequence comprises quantitative information of the body portion; generating, by a processing circuit, an MR image of the body portion based on the MR sequence, wherein each voxel of the MR image represents a volume of the body portion; identifying, by the processing circuit, a part of the MR image representing a bone portion of the body portion; for a voxel of the identified part of the MR image, estimating a bone density of a volume of the bone portion represented by the voxel, based on a quantitative value of the voxel. The quantitative information of the body portion comprises a proton density.

Abstract: A method of visualizing a property of cartilage, comprising: generating, by a processing circuit, a plurality of slices, based on a magnetic resonance, MR, sequence of a portion comprising cartilage, wherein each slice represents a layer of the portion; for each slice, generating, by the processing circuit, a cartilage line representing cartilage of the slice; for the cartilage line of each slice, generating, by the processing circuit, an image column for visualizing a cartilage property of the cartilage of the slice; and generating, by the processing circuit, a two-dimensional, 2D, image for visualizing the cartilage property of the cartilage of the portion, based on the generated image columns.

Abstract: A dynamic magnetic resonance angiography, MRA, method, comprising: acquiring, by an MR scanning device, a multi-contrast magnetic resonance, MR, sequence of a portion of a body; identifying, by a processing circuit, blood vessels of the portion by identifying blood of the portion based on predetermined characteristic of blood and the multi-contrast MR sequence; generating, by the processing circuit, a first MRA image frame and a second MRA image frame, based on the multi-contrast MR sequence, respectively visualising a first part and a second part of the identified blood vessels; generating, by the processing circuit, a dynamic MRA image for visualising a dynamic blood flow through a part of the portion, based on the first and second MRA image frame.

Abstract: The present document relates to a method for generating a contrast enhancement map of a portion of a patient. The method comprises acquiring a magnetic resonance, MR, quantification sequence of the portion, wherein the MR quantification sequence comprises quantification information of a longitudinal R1 relaxation rate, R1, and proton density, PD, of the portion, generating an R1 map of the portion based on the MR quantification sequence, wherein a value of R1 for each voxel of the R1 map is determined, generating a PD map of the portion based on the MR quantification sequence, wherein a value of PD for each voxel of the PD map is determined, estimating a R1? map of the portion, based on the PD map and a predetermined relationship of R1 and PD of the portion, wherein an estimated value of R1 for each voxel of the R1? map is calculated, generating a delta R1 map based on the R1 map and the R1? map.

Abstract: A method, device and non-transitory digital storage medium for estimating non-aqueous tissue volume of at least a portion of a subject. The method includes, in a processing unit, obtaining quantitative magnetic resonance properties of the portion of the subject, providing the quantitative magnetic resonance properties as input to a tissue model, and determining the non-aqueous tissue volume of the portion based on the tissue model and the quantitative magnetic resonance properties.

Abstract: The present document relates to a method for generating a contrast enhancement map of a portion of a patient. The method comprises acquiring a magnetic resonance, MR, quantification sequence of the portion, wherein the MR quantification sequence comprises quantification information of a longitudinal R1 relaxation rate, R1, and proton density, PD, of the portion, generating an R1 map of the portion based on the MR quantification sequence, wherein a value of R1 for each voxel of the R1 map is determined, generating a PD map of the portion based on the MR quantification sequence, wherein a value of PD for each voxel of the PD map is determined, estimating a R1? map of the portion, based on the PD map and a predetermined relationship of R1 and PD of the portion, wherein an estimated value of R1 for each voxel of the R1? map is calculated, generating a delta R1 map based on the R1 map and the R1? map.

Abstract: A magnetic resonance imaging apparatus and method simultaneously measure physical properties including relaxation rates, proton densities, and apparent diffusion coefficients of a subject. The apparatus and method use a single magnetic resonance acquisition of the subject in order to measure the physical properties.

Abstract: A computerized method of generating a map of myelin tissue of a brain is described. In addition sub-maps of different myelin contents can be imaged. The method uses a simulation model comprising at least two interacting tissue compartments.

Abstract: A method, device and non-transitory digital storage medium for estimating non-aqueous tissue volume of at least a portion of a subject. The method includes, in a processing unit, obtaining quantitative magnetic resonance properties of the portion of the subject, providing the quantitative magnetic resonance properties as input to a tissue model, and determining the non-aqueous tissue volume of the portion based on the tissue model and the quantitative magnetic resonance properties.

Abstract: Magnetic resonance (MR) imaging methods and apparatus for simultaneous measurement of the physical properties R1 relaxation rate, R2 relaxation rate, proton density (PD), and apparent diffusion coefficient using a single magnetic resonance acquisition using a single gradient echo acquisition type. A method includes, from an MR scanner, obtaining at least three parallel, segmented gradient-echo acquisitions of a common acquisition type; in a computer, interleaving the at least three parallel, segmented gradient-echo acquisitions with a R1-sensitizing phase, a R2 sensitizing phase and a delay time; and in the computer, generating measures for R1 relaxation rate and R2 relaxation rate and PD from the at least three parallel, segmented gradient-echo acquisitions, thereby simultaneously estimating multiple physical parameters using the single gradient echo acquisition type.

Abstract: Magnetic resonance imaging methods and apparatus for simultaneous measurement of the physical properties R1 and R2 relaxation rate, proton density, and apparent diffusion coefficient using a single magnetic resonance acquisition.

Abstract: A magnetic resonance sequence includes an interleaved slice-selective pre-pulse and a slice-selective multi-echo acquisition. This sequence is repeated with different delays between the pre-pulse and the acquisition resulting in a matrix of complex images. Based on this matrix T1 and T2 relaxations, proton density and the B1 field can be estimated. These quantified parameters enable synthetic magnetic resonance imaging (MRI) and form a robust input for tissue segmentation in computer aided diagnosis for MRI.

Abstract: In a magnetic resonance imaging display system, the brain parenchymal fraction, a clinical measure for brain atrophy, is found by selection of white matter, grey matter, and/or cerebrospinal fluid based on quantitative magnetic resonance properties.

Abstract: In a method and a device MR images having various contrasts are scanned and then values for some or all of the parameters T1, T2 and PD related to the scanned MR images are determined. Based on the scanned MR images and the determined parameter values an initial conventional MR contrast image with some default scanner settings is generated, or alternatively, a stronger non-physical MR contrast image. The initial MR contrast image can then be manipulated by a user in response to movement of a user-controlled marker on a screen showing the contrast image such that a contrast optimized image can be obtained for a particular diagnosis in a very short time. Furthermore a quantitative image can be generated representing the amount of a single tissue type.

Abstract: A computerized method of generating a map of myelin tissue of a brain is described. In addition sub-maps of different myelin contents can be imaged. The method uses a simulation model comprising at least two interacting tissue compartments.

Abstract: A segmented MR image is provided by measuring a number of Magnetic Resonance Imaging parameters on an absolute scale. For example T1 relaxation, T2 relaxation and Proton Density PD can be measured on an absolute scale. The absolute values are then compared with known values for at least one type of tissue. For human tissue these parameters typically are in the order 300-4500 ms for T1, 50-1000 ms for T2 and 0-100% water for PD. Both T1 and T2 depend on the field strength. Based on a comparison between normal values for a particular type of tissue the values obtained for the image each pixel/voxel can be labeled with a certain probability that the voxel contains this type of tissue and segmented accordingly.

Abstract: Magnetic resonance imaging methods and apparatus for simultaneous measurement of the physical properties R1 and R2 relaxation rate, proton density, and apparent diffusion coefficient using a single magnetic resonance acquisition.

Abstract: In a magnetic resonance imaging display system, the brain parenchymal fraction, a clinical measure for brain atrophy, is found by selection of white matter, grey matter, and/or cerebrospinal fluid based on quantitative magnetic resonance properties.