Patents by Inventor Marcela De Leon Gatti

Marcela De Leon Gatti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of biological conjugates by size exclusion chromatography
    Patent number: 10023607
    Abstract: A method for separating a biological conjugate from an aggregate. The molecular weight of the biological conjugate ranges from about 10 kDa to about 1000 kDa. In one embodiment, the method comprises the steps of: (e) providing a mixture comprising the biological conjugate and the aggregate, wherein the biological conjugate has a molecular weight of from about 10 kDa to about 1000 kDa; (f) providing a chromatography column containing a gel, wherein the gel comprises at least one polysaccharide; (g) introducing the mixture of step (a) into the chromatography column; (h) recovering the biological conjugate from the column.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: July 17, 2018
    Assignee: Abbott Laboratories
    Inventors: Marcela De Leon Gatti, Yingqing Huang, David K. Schisla, Lou-Hwa J. Sheu, Christopher A. Tomas
  • PURIFICATION OF BIOLOGICAL CONJUGATES BY SIZE EXCLUSION CHROMATOGRAPHY
    Publication number: 20140066605
    Abstract: A method for separating a biological conjugate from an aggregate. The molecular weight of the biological conjugate ranges from about 10 kDa to about 1000 kDa. In one embodiment, the method comprises the steps of: (e) providing a mixture comprising the biological conjugate and the aggregate, wherein the biological conjugate has a molecular weight of from about 10 kDa to about 1000 kDa; (f) providing a chromatography column containing a gel, wherein the gel comprises at least one polysaccharide; (g) introducing the mixture of step (a) into the chromatography column; (h) recovering the biological conjugate from the column.
    Type: Application
    Filed: February 21, 2013
    Publication date: March 6, 2014
    Applicant: ABBOTT LABORATORIES
    Inventors: Marcela De Leon Gatti, Yingqing Huang, David K. Schisla, Lou-Hwa J. Sheu, Christopher A. Tomas
  • PURIFICATION OF BIOLOGICAL CONJUGATES BY SIZE EXCLUSION CHROMATOGRAPHY
    Publication number: 20100056766
    Abstract: A method for separating a biological conjugate from an aggregate. The molecular weight of the biological conjugate ranges from about 10 kDa to about 1000 kDa. In one embodiment, the method comprises the steps of: (e) providing a mixture comprising the biological conjugate and the aggregate, wherein the biological conjugate has a molecular weight of from about 10 kDa to about 1000 kDa; (f) providing a chromatography column containing a gel, wherein the gel comprises at least one polysaccharide; (g) introducing the mixture of step (a) into the chromatography column; (h) recovering the biological conjugate from the column.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 4, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Marcela De Leon Gatti, Yingqing Huang, David K. Schisla, Lou-Hwa J. Sheu, Christopher A. Tomas