Patents by Inventor Marcelo Baru
Marcelo Baru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11745007Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.Type: GrantFiled: November 19, 2020Date of Patent: September 5, 2023Assignee: BIOTRONIK SE & Co. KGInventors: Andrew B. Kibler, Marcelo Baru, Dirk Muessig
-
Publication number: 20230264015Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.Type: ApplicationFiled: April 28, 2023Publication date: August 24, 2023Inventors: ANDREW B. KIBLER, MARCELO BARU, DIRK MUESSIG
-
Patent number: 11357985Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.Type: GrantFiled: January 31, 2020Date of Patent: June 14, 2022Assignee: Lungpacer Medical Inc.Inventors: Ramasamy Meyyappan, Joaquin Andres Hoffer, Marcelo Baru, Bernard Coquinco, Rodrigo Andres Sandoval, Jessica Kit-Sum Tang
-
Publication number: 20220023625Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.Type: ApplicationFiled: October 12, 2021Publication date: January 27, 2022Applicant: Lungpacer Medical Inc.Inventors: Ramasamy MEYYAPPAN, Joaquin Andres HOFFER, Marcelo BARU, Bernard COQUINCO, Rodrigo Andres SANDOVAL, Jessica Kit-Sum TANG
-
Publication number: 20210283398Abstract: A device for neurostimulation includes a pulse generator for generating current having pulses and at least one first pair of electrodes connected to the pulse generator. The device provides a user-programmable therapy strength parameter configuration and at least two current parameter configurations for neurostimulation stored in the pulse generator. The current parameter configurations are controlled by the therapy strength configuration, at least one of the current parameter configurations is associated with a level of paresthesia sensation of a patient and at least one of the current parameter configurations is associated with a paresthesia-free therapy for the patient. The association between therapy strength parameter and current parameter configurations uniquely adjusts the current parameter configurations based on paresthesia or paresthesia-free intent, when neurostimulation is performed using parameter configurations.Type: ApplicationFiled: May 27, 2021Publication date: September 16, 2021Inventors: ANDREW B. KIBLER, DIRK MUESSIG, MARCELO BARU
-
Patent number: 11116974Abstract: A device for neurostimulation includes a pulse generator for generating current having pulses and at least one first pair of electrodes connected to the pulse generator. The device provides a user-programmable therapy strength parameter configuration and at least two current parameter configurations for neurostimulation stored in the pulse generator. The current parameter configurations are controlled by the therapy strength configuration, at least one of the current parameter configurations is associated with a level of paresthesia sensation of a patient and at least one of the current parameter configurations is associated with a paresthesia-free therapy for the patient. The association between therapy strength parameter and current parameter configurations uniquely adjusts the current parameter configurations based on paresthesia or paresthesia-free intent, when neurostimulation is performed using parameter configurations.Type: GrantFiled: March 19, 2018Date of Patent: September 14, 2021Assignee: BIOTRONIK SE & Co. KGInventors: Andrew B. Kibler, Dirk Muessig, Marcelo Baru
-
Patent number: 11071867Abstract: An implantable medical system for intra-body communication, comprising an implantable first device. The first device comprises a plurality of capacitors and a DC blocking capacitor. The first device is configured to discharge the plurality of capacitors via the DC blocking capacitor in an encoded sequence to generate a signal.Type: GrantFiled: November 21, 2019Date of Patent: July 27, 2021Assignee: BIOTRONIK SE & Co. KGInventors: Marcelo Baru, Brian M. Taff, Andrew B. Kibler
-
Publication number: 20210178161Abstract: An electrical stimulation system includes a plurality of electrodes, a pulse generator (10) configured to generate a constant current pulse in a stimulation path between at least two electrodes of the plurality of electrodes during an active phase, where the pulse generator is configured to provide an output voltage overhead (V) for generating the constant current pulse. The output voltage (V) tracks a voltage ramp (VTrack) throughout the active phase, where the voltage ramp corresponds to a linear approximation of an accumulated voltage in an effective capacitance (Ceff) of the stimulation path throughout the active phase.Type: ApplicationFiled: December 9, 2020Publication date: June 17, 2021Inventor: Marcelo BARU
-
Publication number: 20210069494Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N-1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N-1 electrodes.Type: ApplicationFiled: November 19, 2020Publication date: March 11, 2021Inventors: ANDREW B. KIBLER, MARCELO BARU, DIRK MUESSIG
-
Patent number: 10870000Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.Type: GrantFiled: March 9, 2018Date of Patent: December 22, 2020Assignee: BIOTRONIK SE & Co. KGInventors: Andrew B. Kibler, Marcelo Baru, Dirk Muessig
-
Patent number: 10842996Abstract: A device for neurostimulation including an electrode structure for delivering stimulation pulses to a nerve as well as for processing and extracting evoked compound action potentials, wherein the electrode structure comprises at least a first anode, at least a second anode opposing the first anode and a plurality of cathodes arranged between said anodes, wherein said cathodes are asymmetrically arranged with respect to said at least first and second anode to permit evoked compound action potential sensing via the anode electrodes simultaneously with stimulation.Type: GrantFiled: July 11, 2018Date of Patent: November 24, 2020Assignee: BIOTRONIK SE & Co. KGInventors: Marcelo Baru, Andrew B. Kibler
-
Publication number: 20200188681Abstract: An implantable medical system for intra-body communication, comprising an implantable first device. The first device comprises a plurality of capacitors and a DC blocking capacitor. The first device is configured to discharge the plurality of capacitors via the DC blocking capacitor in an encoded sequence to generate a signal.Type: ApplicationFiled: November 21, 2019Publication date: June 18, 2020Inventors: Marcelo Baru, Brian M. Taff, Andrew B. Kibler
-
Publication number: 20200164207Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.Type: ApplicationFiled: January 31, 2020Publication date: May 28, 2020Applicant: Lungpacer Medical Inc.Inventors: Ramasamy MEYYAPPAN, Joaquin Andres HOFFER, Marcelo BARU, Bernard COQUINCO, Rodrigo Andres SANDOVAL, Jessica Kit-Sum TANG
-
Patent number: 10589097Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.Type: GrantFiled: July 2, 2019Date of Patent: March 17, 2020Assignee: Lungpacer Medical Inc.Inventors: Ramasamy Meyyappan, Joaquin Andres Hoffer, Marcelo Baru, Bernard Coquinco, Rodrigo Andres Sandoval, Jessica Kit-Sum Tang
-
Patent number: 10561844Abstract: Diaphragm pacing systems and methods are disclosed for providing respiratory therapy to a patient. The diaphragm pacing systems can provide rapid insertion and deployment of pacing electrodes in critically ill patients who require intubation and invasive Positive Pressure Mechanical Ventilation (PPMV) in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation. The diaphragm pacing systems can be designed to seamlessly interface with any commercially available positive-pressure ventilatory assistance/support equipment such as is commonly in use in hospital intensive care units (ICU) for treating critically ill patients with breathing insufficiencies, pain, trauma, sepsis or neurological diseases or deficits.Type: GrantFiled: August 27, 2018Date of Patent: February 18, 2020Assignee: Lungpacer Medical Inc.Inventors: Ramasamy Meyyappan, Joaquin Andres Hoffer, Marcelo Baru, Bernard Coquinco, Rodrigo Andres Sandoval, Jessica Kit-Sum Tang
-
Patent number: 10537742Abstract: A pacing system, which is particularly suitable for implantable leadless pacemakers, applies passively-balanced voltage-based pacing pulses, and periodically performs capture verification (evoked response detection) by following a pacing pulse with a current-based active balancing pulse, and then measuring any evoked response provoked by the pacing pulse. The active balancing pulse reduces residual charge on the electrodes used for pulsing, and thereby reduces polarization artifacts that could obscure measurement of the evoked response at the electrodes. The amplitude and pulse width of the active balancing current pulse are defined by measurements made in a few preceding pulses. The pacemaker preferably detects indicia of cardiac contractility, and performs capture verification only when contractility indicates that the patient is physically inactive and emotionally stable.Type: GrantFiled: December 22, 2017Date of Patent: January 21, 2020Assignee: BIOTRONIK SE & Co. KGInventors: Marcelo Baru, Ramprasad Vijayagopal, Alan Fryer
-
Publication number: 20190321632Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.Type: ApplicationFiled: July 2, 2019Publication date: October 24, 2019Applicant: Lungpacer Medical, Inc.Inventors: Ramasamy MEYYAPPAN, Joaquin Andres HOFFER, Marcelo BARU, Bernard COQUINCO, Rodrigo Andres SANDOVAL, Jessica Kit-Sum TANG
-
Patent number: 10406367Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.Type: GrantFiled: August 24, 2018Date of Patent: September 10, 2019Assignee: Lungpacer Medical Inc.Inventors: Ramasamy Meyyappan, Joaquin Andres Hoffer, Marcelo Baru, Bernard Coquinco, Rodrigo Andres Sandoval, Jessica Kit-Sum Tang
-
Publication number: 20190255333Abstract: A medical device for electrical stimulation includes at least two electrodes and electric circuitry for performing active charge compensation. The electrodes are connected to the electric circuitry and the electric circuitry is configured to perform the active charge compensation using a passive element or an active element. A method for controlling a medical device and a medical device system are also disclosed.Type: ApplicationFiled: January 22, 2019Publication date: August 22, 2019Inventors: MARCELO BARU, BRAD MCMILLAN, ASHOK NEDUNGADI
-
Publication number: 20190175904Abstract: An implantable pulse generator configured to deliver first and second stimulation pulse trains wherein the first and second trains are delivered simultaneously, are delivered at different frequencies, and are each biphasic, including a stimulation phase followed by a balancing phase.Type: ApplicationFiled: December 13, 2018Publication date: June 13, 2019Applicant: BIOTRONIK SE &. Co. KGInventors: Marcelo BARU, Alan FRYER