Patents by Inventor Marcelo Bigal

Marcelo Bigal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
    Patent number: 9896502
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms and/or headaches (e.g., migraine, cluster headache, and tension headache) by administering an anti-CGRP antagonist antibody. Compositions for use in the disclosed methods are also provided. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: February 20, 2018
    Assignee: Teva Pharmaceuticals International GmbH
    Inventors: Marcelo Bigal, Sarah Walter, Henry Stern, Michael Chang
  • PREVENTING, TREATING, AND REDUCING (PERSISTENT) POST-TRAUMATIC HEADACHE
    Publication number: 20170088612
    Abstract: Disclosed herein are methods of treating or reducing incidence of post-traumatic headache and/or at least one secondary symptom associated with post-traumatic headache in a subject comprising administering to the subject a monoclonal antibody that modulates the CGRP pathway. Compositions for use in the disclosed methods are also provided. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 30, 2017
    Inventor: Marcelo Bigal
  • ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE AND METHODS USING SAME
    Publication number: 20150322142
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms and/or headaches (e.g., migraine, cluster headache, and tension headache) by administering an anti-CGRP antagonist antibody. Compositions for use in the disclosed methods are also provided. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Application
    Filed: May 13, 2015
    Publication date: November 12, 2015
    Inventors: Marcelo BIGAL, Sarah Walter, Henry Stern, Michael Chang
  • ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE AND METHODS USING SAME
    Publication number: 20150266948
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms and/or headaches (e.g., migraine, cluster headache, and tension headache) by administering an anti-CGRP antagonist antibody. Compositions for use in the disclosed methods are also provided. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Application
    Filed: March 20, 2015
    Publication date: September 24, 2015
    Inventors: Marcelo Bigal, Sarah Walter, Henry Stern, Michael Chang