Patents by Inventor Marcelo Rubinstein

Marcelo Rubinstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Systems for Diagnosis of Non-Central Nervous System (CNS) Diseases in CNS Samples
    Publication number: 20110251077
    Abstract: The invention features methods, systems, and compositions for diagnosing non-central nervous system (non-CNS) disorders by detecting changes in gene expression in the CNS, e.g., in cerebrospinal fluid, in brain or spinal cord tissue samples, or other bodily fluid samples.
    Type: Application
    Filed: February 28, 2011
    Publication date: October 13, 2011
    Inventors: Osvaldo L. Podhajcer, Fernando Juan Pitossi, Marcelo Rubinstein
  • Upstream control elements of the proopiomelanocortin gene and their use
    Patent number: 7745604
    Abstract: The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: June 29, 2010
    Assignee: Oregon Health & Science University
    Inventors: Malcolm J. Low, Marcelo Rubinstein, Flavio Silva Junqueira de Souza
  • Upstream control elements of the proopiomelanocortin gene and their use
    Publication number: 20070059797
    Abstract: The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
    Type: Application
    Filed: August 10, 2006
    Publication date: March 15, 2007
    Inventors: Malcolm Low, Marcelo Rubinstein, Flavio de Souza
  • Methods and systems for diagnosis of non-central nervous system (cns) diseases in cns samples
    Publication number: 20060263783
    Abstract: The invention features methods, systems, and compositions for diagnosing noncentral nervous system (non-CNS) disorders by detecting changes in gene expression in the CNS, e.g., in cerebrospinal fluid, in brain or spinal cord tissue samples, or other bodily fluid samples.
    Type: Application
    Filed: July 2, 2004
    Publication date: November 23, 2006
    Inventors: Osvaldo Podhajcer, Fernando Pitossi, Marcelo Rubinstein
  • Upstream control elements of the proopiomelanocortin gene and their use
    Patent number: 7125979
    Abstract: The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
    Type: Grant
    Filed: January 3, 2003
    Date of Patent: October 24, 2006
    Assignee: Oregon Health & Science University
    Inventors: Malcolm J. Low, Marcelo Rubinstein, Flavio Silva Junqueira de Souza
  • Upstream control elements of the proopiomelanocortin gene and their use
    Publication number: 20040003422
    Abstract: The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
    Type: Application
    Filed: January 3, 2003
    Publication date: January 1, 2004
    Applicant: Oregon Health & Science University
    Inventors: Malcolm J. Low, Marcelo Rubinstein, Flavio Silva Junqueira de Souza