Patents by Inventor Marcia Dougan MOORE

Marcia Dougan MOORE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating breast cancer with tetrahydronaphthalene derivatives as estrogen receptor degraders
    Patent number: 12208095
    Abstract: The present application relates to treating and/or preventing breast cancer, including locally advanced or metastatic, ER+, HER2? breast cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, R4, m, and n are defined herein.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: January 28, 2025
    Assignee: Arvinas Operations, Inc.
    Inventors: Andrew P. Crew, John Flanagan, Sheryl Maxine Gough, Royal J. Haskell, III, Marcia Dougan Moore, Yimin Qian, Ian Charles Anthony Taylor, Jing Wang
  • METHODS OF TREATING PROSTATE CANCER
    Publication number: 20230128132
    Abstract: The present application relates to treating and/or preventing prostate cancer, including metastatic and/or castrate-resistant prostate cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, X1, X2, X3, X4, and n are defined herein.
    Type: Application
    Filed: December 21, 2022
    Publication date: April 27, 2023
    Applicant: Arvinas Operations, Inc.
    Inventors: Andrew P. CREW, Lawrence B. SNYDER, Jing WANG, Royal J. HASKELL, III, Marcia Dougan MOORE
  • METHODS OF TREATING BREAST CANCER WITH TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADER
    Publication number: 20220193072
    Abstract: The present application relates to treating and/or preventing breast cancer, including locally advanced or metastatic, ER+, HER2? breast cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, R4, m, and n are defined herein.
    Type: Application
    Filed: December 13, 2021
    Publication date: June 23, 2022
    Inventors: Xin CHEN, Andrew P. CREW, John FLANAGAN, Sheryl Maxine GOUGH, Royal J. HASKELL, III, Marcia Dougan MOORE, Yimin QIAN, Ian Charles Anthony TAYLOR, Jing WANG
  • METHODS OF TREATING PROSTATE CANCER
    Publication number: 20210113557
    Abstract: The present application relates to treating and/or preventing prostate cancer, including metastatic and/or castrate-resistant prostate cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, X1, X2, X3, X4 and n are defined herein.
    Type: Application
    Filed: October 21, 2020
    Publication date: April 22, 2021
    Inventors: Andrew P. CREW, Lawrence B. SNYDER, Jing WANG, Royal J. HASKELL, III, Marcia Dougan MOORE
  • METHODS OF TREATING BREAST CANCER WITH TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS
    Publication number: 20210060008
    Abstract: The present application relates to treating and/or preventing breast cancer, including locally advanced or metastatic, ER+, HER2? breast cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, R4, m, and n are defined herein.
    Type: Application
    Filed: August 24, 2020
    Publication date: March 4, 2021
    Inventors: Xin CHEN, Andrew P. CREW, John FLANAGAN, Sheryl Maxine GOUGH, Royal J. HASKELL, III, Marcia Dougan MOORE, Yimin QIAN, Ian Charles Anthony TAYLOR, Jing WANG