Patents by Inventor Marcia K. Wolf

Marcia K. Wolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transformed bacteria producing CS6 antigens as vaccines
    Patent number: 7118758
    Abstract: Disclosed herein are antigens that stimulate protective antibodies against enterotoxigenic Escherichia coli. Also disclosed herein are proteins encoded by cssA and cssB genes as well as constructs containing the genes and methods of using thereof.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: October 10, 2006
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Marcia K. Wolf, Fred J. Cassels, Edgar Charles Boedeker
  • Transformed bacteria producing CS6 antigens as vaccines
    Publication number: 20040156829
    Abstract: Disclosed herein are antigens that stimulate protective antibodies against enterotoxigenic Escherichia coli. Also disclosed herein are proteins encoded by cssA and cssB genes as well as constructs containing the genes and methods of using thereof.
    Type: Application
    Filed: February 2, 2004
    Publication date: August 12, 2004
    Applicant: United States Army
    Inventors: Marcia K. Wolf, Fred J. Cassels, Edgar Charles Boedeker
  • Methods for production of antigens under control of temperature-regulated promotors in enteric bacteria
    Patent number: 5698416
    Abstract: Production of proteins in bacteria containing DNA sequences encoding proteins under the control of a temperature-regulated promotor is improved by growing the organisms at temperatures of less than 35.degree. C. until the late logarithmic phase. Thereafter the temperature may be raised to 36.degree. C. to 39.degree. C. Antigens produced by the method of the invention may be used as vaccines, as means for measuring efficacy of vaccines, as probes to detect antigens from clinical samples and for biochemical characterization of antigens.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: December 16, 1997
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Marcia K. Wolf, Frederick J. Cassels, Brian A. Bell