Abstract: Disclosed are hydrophilic porous PTFE membranes comprising PTFE and an amphiphilic copolymer of the formula (I): wherein Rf, Rh1, Rh2, Y, m, n, and o are as described herein. Also disclosed are a method of preparing hydrophilic porous PTFE membranes and a method of filtering fluids through such membranes.

Abstract: Disclosed is a self-wetting porous membrane comprising an aromatic hydrophobic polymer such as polysulfone and a wetting agent comprising a copolymer of formula A-B or A-B-A, wherein A is a hydrophilic segment comprising a polymerized monomer of the formula (I): CH2?C(R1)(R2), wherein R1 and R2 are as described herein, and B is polyethersulfone, wherein segments B and A are linked through an oxygen atom. Also disclosed is a method of preparing a self-wetting membrane comprising casting a solution containing an aromatic hydrophobic polymer and the wetting agent, followed by subjecting the cast solution to phase inversion. The self-wetting porous membrane finds use in hemodialysis, microfiltration, and ultrafiltration.

Abstract: Disclosed are copolymers suitable for hydrophilically modifying the surface of porous fluoropolymer supports, for example, a copolymer of the formula (I) or (II): wherein Rf, Rh, Ra, Y, m, and n are as described herein. Also disclosed are a method of preparing the copolymers, a method of hydrophilically modifying porous fluoropolymer supports, hydrophilic fluoropolymer porous membranes prepared from the polymers, and a method of filtering fluids through the porous membranes.

Abstract: Disclosed is a self-wetting porous membrane comprising an aromatic hydrophobic polymer such as polysulfone and a wetting agent comprising a copolymer of formula A-B or A-B-A, wherein A is a hydrophilic segment comprising a polymerized monomer of the formula (I): CH2?C(R1)(R2), wherein R1 and R2 are as described herein, and B is an aromatic hydrophobic polymeric segment, wherein segments B and A are linked through an amidoalkylthio group. Also disclosed is a method of preparing a self-wetting membrane comprising casting a solution containing an aromatic hydrophobic polymer and the wetting agent, followed by subjecting the cast solution to phase inversion. The self-wetting porous membrane finds use in hemodialysis, microfiltration, and ultrafiltration.

Abstract: Disclosed are copolymers suitable for hydrophilically modifying the surface of fluoropolymer membranes. An example of the copolymers is: Also disclosed are a method of preparing the copolymers, a method of hydrophilically modifying porous fluoropolymer supports, hydrophilic porous fluoropolymer membranes prepared from the copolymers, and a method of filtering fluids by the use of the hydrophilic porous fluoropolymer membranes.

Abstract: Disclosed are hydrophilic porous PTFE membranes comprising PTFE and an amphiphilic copolymer, for example, a copolymer of the formula: wherein m and n are as described herein. Also disclosed are a method of preparing hydrophilic porous PTFE membranes and a method of filtering fluids through such membranes.

Abstract: Disclosed are copolymers which are useful in hydrophilically modifying fluoropolymer membranes. An example of the copolymers is: Also disclosed are a method of preparing such copolymers, a method of modifying fluoropolymer membrane surfaces, and hydrophilic fluoropolymer porous membranes prepared from the copolymers.

Abstract: Disclosed are hydrophilic porous PTFE membranes comprising PTFE and an amphiphilic copolymer of the formula (I): wherein Rf, Rh1, Rh2, Y, m, n, and o are as described herein. Also disclosed are a method of preparing hydrophilic porous PTFE membranes and a method of filtering fluids through such membranes.

Abstract: Disclosed are hydrophilic porous PTFE membranes comprising PTFE and an amphiphilic copolymer, for example, a copolymer of the formula: wherein m and n are as described herein. Also disclosed are a method of preparing hydrophilic porous PTFE membranes and a method of filtering fluids through such membranes.

Abstract: Disclosed is a self-wetting porous membrane comprising an aromatic hydrophobic polymer such as polysulfone and a wetting agent comprising a copolymer of formula A-B or A-B-A, wherein A is a hydrophilic segment comprising a polymerized monomer of the formula (I): CH2?C(R1)(R2), wherein R1 and R2 are as described herein, and B is an aromatic hydrophobic polymeric segment, wherein segments B and A are linked through an amidoalkylthio group. Also disclosed is a method of preparing a self-wetting membrane comprising casting a solution containing an aromatic hydrophobic polymer and the wetting agent, followed by subjecting the cast solution to phase inversion. The self-wetting porous membrane finds use in hemodialysis, microfiltration, and ultrafiltration.

Abstract: Disclosed is a self-wetting porous membrane comprising an aromatic hydrophobic polymer such as polysulfone and a wetting agent comprising a copolymer of formula A-B or A-B-A, wherein A is a hydrophilic segment comprising a polymerized monomer of the formula (I): CH2?C(R1)(R2), wherein R1 and R2 are as described herein, and B is polyethersulfone, wherein segments B and A are linked through an oxygen atom. Also disclosed is a method of preparing a self-wetting membrane comprising casting a solution containing an aromatic hydrophobic polymer and the wetting agent, followed by subjecting the cast solution to phase inversion. The self-wetting porous membrane finds use in hemodialysis, microfiltration, and ultrafiltration.

Abstract: Disclosed are copolymers suitable for hydrophilically modifying the surface of porous fluoropolymer supports, for example, a copolymer of the formula (I) or (II): wherein Rf, Rh, Ra, Y, m, and n are as described herein. Also disclosed are a method of preparing the copolymers, a method of hydrophilically modifying porous fluoropolymer supports, hydrophilic fluoropolymer porous membranes prepared from the polymers, and a method of filtering fluids through the porous membranes.

Abstract: Disclosed are copolymers suitable for hydrophilically modifying the surface of fluoropolymer membranes. An example of the copolymers is: Also disclosed are a method of preparing the copolymers, a method of hydrophilically modifying porous fluoropolymer supports, hydrophilic porous fluoropolymer membranes prepared from the copolymers, and a method of filtering fluids by the use of the hydrophilic porous fluoropolymer membranes.

Abstract: Disclosed are copolymers which are useful in hydrophilically modifying fluoropolymer membranes. An example of the copolymers is: Also disclosed are a method of preparing such copolymers, a method of modifying fluoropolymer membrane surfaces, and hydrophilic fluoropolymer porous membranes prepared from the copolymers.

Abstract: This invention provides compounds of the formula: wherein X is wherein R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring and all other variables are as defined herein, their use in pulmonary inflammation or bronchoconstriction therapy and compositions comprising and processes for preparing the same are provided.

Abstract: Provided are compounds of Formula I: wherein X is: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.

Abstract: This invention provides compounds of the formula: wherein X is wherein R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring and all other variables are as defined herein, their use in pulmonary inflammation or bronchoconstriction therapy and compositions comprising and processes for preparing the same are provided.

Abstract: This invention provides compounds of the formula: wherein X is wherein R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring and all other variables are as defined herein, their use in pulmonary inflammation or bronchoconstriction therapy and compositions comprising and processes for preparing the same are provided.

Abstract: Provided are compounds of Formula I: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.

Abstract: Provided are compounds of Formula I: wherein X is: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.