Patents by Inventor Marcio Scorsin
Marcio Scorsin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240100071Abstract: Subject matter of the present invention is a combination medication for use in the treatment of a patient having acute and/or persistent dyspnea comprising at least two of the following components: a beta blocker, and one agent of the group consisting of an angiotensin-converting enzyme (ACE) inhibitor, an angiotensin II inhibitor and a combination of angiotensin II inhibitor or an angiotensin receptor-neprilysin inhibitor (ARNi), and mineralo receptor antagonist (MRA), gliflozine, a loop-acting diuretic, wherein a sample of bodily fluid of said patient has a level of BNP>200 pg/mL and/or has a level NT-proBNP>600 pg/mL, and wherein said sample of bodily fluid is selected from the group comprising blood, plasma and serum, and wherein said patient is either a patient with heart failure with left ventricular ejection fraction (LVEF) greater and equal to 40%, preferably 50%, or a patient with no heart failure.Type: ApplicationFiled: December 15, 2021Publication date: March 28, 2024Applicant: S-Form PharmaInventors: Eric HALIOUA, Marcio SCORSIN, Alexandre MEBAZAA
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Patent number: 11896486Abstract: Transcatheter delivery system for a self-expandable heart valve prosthesis (29) comprising a handle (17, 17?), a hollow shaft (6) a distal tip (1, 1?, 1??) and an actuation mechanism for moving a valve prosthesis (29) towards said distal tip (1, 1?, 1??) or said handle (17, 17?), said hollow shaft (6) being adapted to slidingly receive a compressed valve prosthesis (29); the system being characterized by the fact that it includes a valve prosthesis crimping tool that comprises a hollow conical element (21), a detachable transfer tube (24) and a pulling device (26); said conical element (21) being adapted to let a valve prosthesis (29) in an expanded state enter the conical element (21) through its basis and enter said transfer tube (24) in a compressed state, said valve prosthesis (29) being pulled by said pulling device (26) when crossing said conical element (21) and entering said transfer tube (24), said transferring tube (24) being adapted to be temporarily connected to said conical element (21).Type: GrantFiled: March 1, 2018Date of Patent: February 13, 2024Assignee: EPYGONInventors: Enrico Pasquino, Marcio Scorsin, Andrea Marchisio, Lorenzo Valerio, Stefano Pasquino
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Patent number: 11660375Abstract: The invention concerns the treatment of bioprosthetic tissues a Cyclodextrin, preferably in association with Ethanol.Type: GrantFiled: November 30, 2017Date of Patent: May 30, 2023Assignee: EpygonInventors: Enrico Pasquino, Marcio Scorsin
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Patent number: 11583395Abstract: Prosthetic heart valve leaflet with a fixed end and a free end characterized by the fact that it has a variable thickness.Type: GrantFiled: January 19, 2018Date of Patent: February 21, 2023Assignee: EPYGONInventors: Enrico Pasquino, Marcio Scorsin
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Publication number: 20210213169Abstract: The invention concerns the treatment of bioprosthetic tissues a Cyclodextrin, preferably in association with Ethanol.Type: ApplicationFiled: November 30, 2017Publication date: July 15, 2021Inventors: Enrico Pasquino, Marcio Scorsin
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Publication number: 20210085452Abstract: Prosthetic heart valve leaflet with a fixed end and a free end characterized by the fact that it has a variable thickness.Type: ApplicationFiled: January 19, 2018Publication date: March 25, 2021Inventors: Enrico Pasquino, Marcio Scorsin
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Patent number: 10820988Abstract: An expandable stent-valve has a stent component and a valve component, preferably an aortic valve component, a mitral valve component or a tricuspid valve component. The stent has, an outer surface area structured in a manner such that the surface area has a higher coefficient of friction between the outer surface and a duct wall than an untreated surface area of the stent component. The surface area is preferably structured with micro-incisions or micro-grooves.Type: GrantFiled: April 8, 2014Date of Patent: November 3, 2020Assignee: EPYGONInventors: Marcio Scorsin, Enrico Pasquino
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Patent number: 10806577Abstract: Atrio-ventricular valve stent (1) having a tubular shape, with a sub annular anterior side (2), a sub annular posterior side (3) and sub annular lateral sides (13), the sub annular anterior side (2) comprising a self-folding native leaflet engagement member (4-9) that forms a straight extension of said sub annular anterior side (2) when the stent (1) is collapsed and that is folded on itself when the stent (1) is in an expanded state; said engagement member (4-9) forming an integral part of the stent (1) and wherein each sub annular lateral side (13) is longer than said sub annular anterior side (2) when the stent (1) is in an expanded state.Type: GrantFiled: June 3, 2016Date of Patent: October 20, 2020Assignee: EpygonInventors: Enrico Pasquino, Marcio Scorsin, Stefano Pasquino, Andrea Marchisio, Lorenzo Valerio, Sergio Casalegno, Marco Gard, Pietro Arru
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Publication number: 20200306069Abstract: Crimping device (1) for reducing the diameter of collapsible valves, said device (1) including at least two independent cylindrical crimping units (2, 3, 4) that are each adapted to crimp a different specific part of a valve, independently from the other crimping unit(s), each of said unit (2, 3, 4) comprising a diaphragm rotation crimping mechanism that includes crimping jaws, and wherein each unit (2, 3, 4) comprises an actuator for activating said mechanism, characterized by the fact that said actuator is a handling screw (51, 61, 71) that is tangentially fixed to the external surface of the cylindrical crimping unit (2, 3, 4).Type: ApplicationFiled: December 12, 2018Publication date: October 1, 2020Inventors: Enrico Pasquino, Marcio Scorsin, Lorenzo Valerio, Andrea Marchisio, Davide Gastaldin, Stefano Pasquino
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Patent number: 10779935Abstract: A cardiac stent-valve (1), preferably a mitral stent-valve, comprising a stent component (2) and a valve component (3), wherein the stent component (2) comprises an inflow end (4) and an outflow end (5) and a wall between the inflow (4) and the outflow end (5), and wherein the valve component (3) is made of one single leaflet (6); the periphery of said single leaflet (6) being partially attached or attachable to the stent component (2) along at least fixation lines (7?, 7?), characterized in that said two fixation lines (7?) are at least partially inclined with respect to an annular plane of said valve perpendicular to a flow direction (A) through the stent-valve (1) and wherein the third fixation line (7?) runs parallel with respect to said plane.Type: GrantFiled: February 26, 2015Date of Patent: September 22, 2020Assignee: EpygonInventors: Marcio Scorsin, Enrico Pasquino, Marco Gard, Claudio Piccoli
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Patent number: 10779934Abstract: A prosthetic valve, preferably an expandable prosthetic valve, having a valve component (3), preferably a mitral valve component, made of a single functional leaflet (6) wherein the prosthetic valve (1) comprises at least two tissue supports (4?, 4?,4??,4??) attachable to an inner surface (5) of a stent component (2), wherein at least one tissue support (4?, 4?,4??,4??) comprises at least one attachment area (7?, 7?), at least a section of the attachment area extending essentially inwardly from the inner surface (5), wherein said leaflet (6) is attached to at least one tissue support (4?, 4?,4??,4??) at the section of said attachment area(s) (7?, 7?) such that the leaflet (6) is arranged between said attachment area(s) (7?,7?) or integrally formed with one tissue support (4?,4?,4??,4??) and attached to the second tissue support (4?,4?,4??,4??) at the section of the attachment area(s) (7?,7?).Type: GrantFiled: March 9, 2015Date of Patent: September 22, 2020Assignee: EpygonInventors: Marcio Scorsin, Enrico Pasquino, Sergio Casalegno
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Patent number: 10702252Abstract: Medical device for transcatheter heart valve repair comprising a grasping tweezer (1) and a plicating tweezer (2), said grasping tweezer (1) being adapted to grasp a leaflet rim (3) and said plicating tweezer (2) comprising two rotatable flaps (4,5) and a central shaft (6) around which said flaps (4,5) may rotate in a “butterfly manner”, in such a way that the plicating tweezer (2) may adopt a closed or an open configuration. The invention also relates to a method for using this medical device.Type: GrantFiled: January 8, 2016Date of Patent: July 7, 2020Assignee: EpygonInventors: Enrico Pasquino, Marcio Scorsin
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Publication number: 20200000589Abstract: Transcatheter delivery system for a self-expandable heart valve prosthesis (29) comprising a handle (17, 17?), a hollow shaft (6) a distal tip (1, 1?, 1??) and an actuation mechanism for moving a valve prosthesis (29) towards said distal tip (1, 1?, 1??) or said handle (17, 17?), said hollow shaft (6) being adapted to slidingly receive a compressed valve prosthesis (29); the system being characterized by the fact that it includes a valve prosthesis crimping tool that comprises a hollow conical element (21), a detachable transfer tube (24) and a pulling device (26); said conical element (21) being adapted to let a valve prosthesis (29) in an expanded state enter the conical element (21) through its basis and enter said transfer tube (24) in a compressed state, said valve prosthesis (29) being pulled by said pulling device (26) when crossing said conical element (21) and entering said transfer tube (24), said transferring tube (24) being adapted to be temporarily connected to said conical element (21).Type: ApplicationFiled: March 1, 2018Publication date: January 2, 2020Inventors: Enrico Pasquino, Marcio Scorsin, Andrea Marchisio, Lorenzo Valerio, Stefano Pasquino
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Publication number: 20190240017Abstract: This disclosure discloses various elongated members that are segmentally adjustable. Further, this disclosure discloses various threading devices that can secure various toggles and various locks to various surfaces, whether animate or inanimate. Additionally, this disclosure discloses various techniques of using such elongated members and such threading devices.Type: ApplicationFiled: January 3, 2019Publication date: August 8, 2019Inventors: Luis Jose Almodovar, Marcio Scorsin
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Patent number: 10278814Abstract: Heart valve prosthesis, comprising a ring-shaped supporting structure (3) to be anchored at the valve annulus, and a valve leaflet (5) supported by the supporting structure. The supporting structure comprises a support wall portion (31), at which a root end (51) of the valve leaflet is connected, and a complementary wall portion (32) opposite the support wall portion, which supports a coaptation surface (33) adapted to be sealingly engaged by a free end (52) of the valve leaflet (5), and extending in a direction parallel to the direction of movement of the free end (52) of the valve leaflet (5) at the coaptation surface (33). The free end of the valve leaflet (5) is connected to the support wall portion or to the complementary wall portion by means of a traction member (55), dimensioned in such a way that the free end (52) of the valve leaflet (5) is stopped at the coaptation surface.Type: GrantFiled: April 26, 2013Date of Patent: May 7, 2019Assignee: EPYGONInventors: Marcio Scorsin, Enrico Pasquino
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Publication number: 20180303612Abstract: Atrio-ventricular valve stent (1) having a tubular shape, with a sub annular anterior side (2), a sub annular posterior side (3) and sub annular lateral sides (13), the sub annular anterior side (2) comprising a self-folding native leaflet engagement member (4-9) that forms a straight extension of said sub annular anterior side (2) when the stent (1) is collapsed and that is folded on itself when the stent (1) is in an expanded state; said engagement member (4-9) forming an integral part of the stent (1) and wherein each sub annular lateral side (13) is longer than said sub annular anterior side (2) when the stent (1) is in an expanded state.Type: ApplicationFiled: June 3, 2016Publication date: October 25, 2018Inventors: Enrico Pasquino, Marcio Scorsin, Stefano Pasquino, Andrea Marchisio, Lorenzo Valerio, Sergio Casalegno, Marco Gard, Pietro Arru
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Publication number: 20180000473Abstract: Medical device for transcatheter heart valve repair comprising a grasping tweezer (1) and a plicating tweezer (2), said grasping tweezer (1) being adapted to grasp a leaflet rim (3) and said plicating tweezer (2) comprising two rotatable flaps (4,5) and a central shaft (6) around which said flaps (4,5) may rotate in a “butterfly manner”, in such a way that the plicating tweezer (2) may adopt a closed or an open configuration. The invention also relates to a method for using this medical device.Type: ApplicationFiled: January 8, 2016Publication date: January 4, 2018Inventors: Enrico Pasquino, Marcio Scorsin
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Publication number: 20170065409Abstract: A cardiac stent-valve (1), preferably a mitral stent-valve, comprising a stent component (2) 14 and a valve component (3), wherein the stent component (2) comprises an inflow end (4) and an outflow end (5) and a wall between the inflow (4) and the outflow end (5), and wherein the valve component (3) is made of one single leaflet (6); the periphery of said single leaflet (6) being partially attached or attachable to the stent component (2) along at least fixation lines (7?, 7?), characterized in that said two fixation lines (7?) are at least partially inclined with respect to an annular plane of said valve perpendicular to a flow direction (A) through the stent-valve (1) and wherein the third fixation line (7?) runs parallel with respect to said plane.Type: ApplicationFiled: February 26, 2015Publication date: March 9, 2017Inventors: Marcio Scorsin, Enrico Pasquino, Marco Gard, Claudio Piccoli
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Publication number: 20160367359Abstract: A prosthetic valve, preferably an expandable prosthetic valve, having a valve component (3), preferably a mitral valve component, made of a single functional leaflet (6) wherein the prosthetic valve (1) comprises at least two tissue supports (4?, 4?,4??,4??) attachable to an inner surface (5) of a stent component (2), wherein at least one tissue support (4?, 4?,4??,4??) comprises at least one attachment area (7?, 7?), at least a section of the attachment area extending essentially inwardly from the inner surface (5), wherein said leaflet (6) is attached to at least one tissue support (4?, 4?,4??,4??) at the section of said attachment area(s) (7?, 7?) such that the leaflet (6) is arranged between said attachment area(s) (7?,7?) or integrally formed with one tissue support (4?,4?,4??,4??) and attached to the second tissue support (4?,4?,4??,4??) at the section of the attachment area(s) (7?,7?).Type: ApplicationFiled: March 9, 2015Publication date: December 22, 2016Inventors: Marcio Scorsin, Enrico Pasquino, Sergio Casalegno
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Publication number: 20160302919Abstract: An expandable stent-valve (1), having a stent component (2) and a valve component (3), preferably an aortic valve component, a mitral valve component or a tricuspid valve component, wherein the stent component (2) comprises an outer surface (10, 11, 23) area structured in a manner such that the surface (10, 11, 23) area has a higher coefficient of friction between the outer surface (10, 11, 23) and a duct wall than an untreated surface area of the stent component (2), said surface area preferably being structured with micro-incisions (12) or micro-grooves.Type: ApplicationFiled: April 8, 2014Publication date: October 20, 2016Inventors: Marcio SCORSIN, Enrico PASQUINO