Patents by Inventor Marco Biancucci

Marco Biancucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED BETACORONAVIRUS SPIKE PROTEINS
    Publication number: 20230234992
    Abstract: Betacoronavirus Spike proteins, or fragments thereof, including substitution mutations designed to increase stability, decrease the risk of antibody dependent enhancement, or both; and that are useful in, for example, immunogenic compositions.
    Type: Application
    Filed: June 4, 2021
    Publication date: July 27, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Marco BIANCUCCI, Joel David KARPIAK, Jason Paul LALIBERTE, Anna Ulrika LOWEGARD, Enrico MALITO, Newton Muchugu WAHOME
  • MODIFIED HUMAN CYTOMEGALOVIRUS PROTEINS
    Publication number: 20230201334
    Abstract: Modified HCMV gB proteins in a non-post-fusogenic conformation, compositions comprising such proteins, and uses thereof.
    Type: Application
    Filed: July 22, 2020
    Publication date: June 29, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Marco BIANCUCCI, Sumana CHANDRAMOULI, Newton Muchugu WAHOME
  • ANTIBODIES
    Publication number: 20230174626
    Abstract: Monoclonal antibodies and antigen binding fragments that specifically bind to the Human Cytomegalovirus (HCMV) pentamer protein complex (gH/gL/UL128/UL130/UL131A) or other gH-containing complexes, and uses thereof.
    Type: Application
    Filed: March 25, 2021
    Publication date: June 8, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Marco BIANCUCCI, Sumana CHANDRAMOULI, Kate LUISI
  • BACTERIAL TOXINS AND USES THEREOF AS RAS SPECIFIC PROTEASES FOR TREATING CELL PROLIFERATION DISEASES AND DISORDERS
    Publication number: 20230045284
    Abstract: Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer.
    Type: Application
    Filed: May 17, 2022
    Publication date: February 9, 2023
    Inventors: Karla J.F. Satchell, Irena Antic, Marco Biancucci
  • BACTERIAL TOXINS AND USES THEREOF AS RAS SPECIFIC PROTEASES FOR TREATING CELL PROLIFERATION DISEASES AND DISORDERS
    Publication number: 20210087545
    Abstract: Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer.
    Type: Application
    Filed: November 9, 2020
    Publication date: March 25, 2021
    Inventors: Karla J.F. Satchell, Irena Antic, Marco Biancucci
  • Bacterial toxins and uses thereof as Ras specific proteases for treating cell proliferation diseases and disorders
    Patent number: 10829752
    Abstract: Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: November 10, 2020
    Assignee: Northwestern University
    Inventors: Karla J. F. Satchell, Irena Antic, Marco Biancucci
  • BACTERIAL TOXINS AND USES THEREOF AS RAS SPECIFIC PROTEASES FOR TREATING CELL PROLIFERATION DISEASES AND DISORDERS
    Publication number: 20180305676
    Abstract: Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer.
    Type: Application
    Filed: April 19, 2018
    Publication date: October 25, 2018
    Applicant: Northwestern University
    Inventors: Karla J.F. Satchell, Irena Antic, Marco Biancucci
  • BACTERIAL TOXINS AND USES THEREOF AS RAS SPECIFIC PROTEASES
    Publication number: 20160030531
    Abstract: Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer.
    Type: Application
    Filed: August 3, 2015
    Publication date: February 4, 2016
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Karla J.F. Satchell, Irena Antic, Marco Biancucci