Patents by Inventor Marco Brünjes

Marco Brünjes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of amphiphilic imidazolinium compounds
    Patent number: 10479768
    Abstract: The present invention generally relates to improved processes for the preparation of amphiphilic imidazolinium compounds such as 1-[2-(9(Z)-octadecenoyloxy)ethyl]-2-(8(Z)-heptadecenyl)-3-(2-hydroxyethyl)imidazolinium chloride (DOTIM). In particular, the invention relates to processes for the synthesis of such compounds that avoid the need for toxic reagents, are more economical, and result in less waste than conventional methods. DOTIM and similar compounds can be formulated as cationic liposomes, which are useful as chemical vectors for nucleic acid delivery in gene therapy.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: November 19, 2019
    Assignee: Bayer Animal Health GmbH
    Inventors: Marco Brünjes, Mark James Ford
  • Difluoromethyl-nicotinic-indanyl carboxamides
    Patent number: 10349656
    Abstract: The present invention relates to novel difluoromethyl-nicotinic indanyl carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: July 16, 2019
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Christophe Dubost, Philipp Winter, Marco Brünjes, Mark James Ford, Ulrike Wachendorff-Neumann, Cyril Montagne, Jean-Pierre Vors, Stephane Brunet, Philippe Rinolfi
  • Process for preparing piperidine-4-carbothioamide hydrochloride
    Patent number: 10093626
    Abstract: The present invention describes a novel process for preparing piperidine-4-carbothioamide hydrochloride.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: October 9, 2018
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Marco Bruenjes, Mark James Ford
  • SUBSTITUTED ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS
    Publication number: 20180206495
    Abstract: Substituted aryl- and heteroarylcarbonyl hydrazides The invention relates to substituted aryl- and heteroarylcarbonyl hydrazides of the general formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description for enhancing stress tolerance in plants to abiotic stress, and for enhancing plant growth and/or for increasing plant yield.
    Type: Application
    Filed: July 14, 2016
    Publication date: July 26, 2018
    Inventors: Jens FRACKENPOHL, Guido BOJACK, Marco BRÜNJES, Hendrik HELMKE, Isabelle ADELT, Stefan LEHR, Peter BRÜCHNER, Jan DITTGEN, Dirk SCHMUTZLER, Ines HEINEMANN, Udo BICKERS, Martin Jeffrey HILLS, Juan Pedro RUIZ-SANTAELLA, Harry STREK, Philippe DESBORDES
  • SUBSTITUTED HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS
    Publication number: 20180206498
    Abstract: The invention relates to substituted heteroaryl carboxylic acid hydrazides of general formula (I) or salts thereof, wherein the groups of formula (I) have the definitions stated in the description, for increasing the stress tolerance in plants with respect to abiotic stress, and also for strengthening plant growth and/or for increasing plant yield.
    Type: Application
    Filed: July 14, 2016
    Publication date: July 26, 2018
    Inventors: Jens FRACKENPOHL, Guido BOJACK, Marco BRUENJES, Hendrik HELMKE, Stefan LEHR, Peter BRUECHNER, Joerg TIEBES, Marc MOSRIN, Jan DITTGEN, Dirk SCHMUTZLER, Philippe DESBORDES
  • SUBSTITUTED CYCLIC ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS
    Publication number: 20180206491
    Abstract: The invention relates to substituted cyclic aryl- and heteroarylcarbonyl hydrazides of the general formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description for enhancing stress tolerance in plants to abiotic stress, and for enhancing plant growth and/or for increasing plant yield.
    Type: Application
    Filed: July 12, 2016
    Publication date: July 26, 2018
    Inventors: Jens FRACKENPOHL, Guido BOJACK, Marco BRUENJES, Hendrik HELMKE, Stefen LEHR, Isabelle ADELT, Jan DITTGEN, Udo BICKERS, Martin Jeffrey HILLS, Dirk SCHMUTZLER, Ines HEINEMANN, Juan Pedro RUIZ-SANTAELLA MORENO
  • IMPROVED PROCESS FOR THE PREPARATION OF AMPHIPHILIC IMIDAZOLINIUM COMPOUNDS
    Publication number: 20180148415
    Abstract: The present invention generally relates to improved processes for the preparation of amphiphilic imidazolinium compounds such as 1-[2-(9(Z)-octadecenoyloxy)ethyl]-2-(8(Z)-heptadecenyl)-3-(2-hydroxyethyl)imidazolinium chloride (DOTIM). In particular, the invention relates to processes for the synthesis of such compounds that avoid the need for toxic reagents, are more economical, and result in less waste than conventional methods. DOTIM and similar compounds can be formulated as cationic liposomes, which are useful as chemical vectors for nucleic acid delivery in gene therapy.
    Type: Application
    Filed: May 3, 2016
    Publication date: May 31, 2018
    Inventors: Marco BRÜNJES, Mark James FORD
  • Process for preparing piperidine-4-carbothioamide hydrochloride
    Publication number: 20180044294
    Abstract: The present invention describes a novel process for preparing piperidine-4-carbothioamide hydrochloride.
    Type: Application
    Filed: February 29, 2016
    Publication date: February 15, 2018
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: MARCO BRUENJES, MARK JAMES FORD
  • Preparation of piperidine-4-carbothioamide
    Patent number: 9790182
    Abstract: The present invention describes a novel process for preparing piperidine-4-carbothioamide.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: October 17, 2017
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventors: Marco Brünjes, Mark James Ford
  • Difluoromethyl-nicotinic-indanyl carboxamides
    Publication number: 20170150717
    Abstract: The present invention relates to novel difluoromethyl-nicotinic indanyl carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials.
    Type: Application
    Filed: June 22, 2015
    Publication date: June 1, 2017
    Inventors: Christophe DUBOST, Philipp WINTER, Marco BRÜNJES, Mark James FORD, Ulrike WACHENDORFF-NEUMANN, Cyril MONTAGNE, Jean-Pierre VORS, Stephane BRUNET, Philippe RINOLFI
  • PREPARATION OF PIPERIDINE-4-CARBOTHIOAMIDE
    Publication number: 20170137381
    Abstract: The present invention describes a novel process for preparing piperidine-4-carbothioamide.
    Type: Application
    Filed: June 8, 2015
    Publication date: May 18, 2017
    Applicant: Bayer CropScience Aktiengesellschaft
    Inventors: Marco BRÜNJES, Mark James FORD
  • Herbicidally active 6?-phenyl-2,2?-bipyridine-3-carboxylic acid derivatives
    Patent number: 9409881
    Abstract: There are described 6?-phenyl-2,2?-bipyridine-3-carboxylic acid derivatives of the general formula (I) as herbicides. In this formula (I), R1 to R5 are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen, nitro, cyano and formyl.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: August 9, 2016
    Assignee: Bayer CropScience AG
    Inventors: Michael Gerhard Hoffmann, Uwe Doeller, Marco Bruenjes, Hansjoerg Dietrich, Elmar Gatzweiler, Christopher Hugh Rosinger, Dirk Schmutzler
  • Substituted picolinic acids and pyrimidine-4-carboxylic acids, method for the production thereof and use thereof as herbicides and plant growth regulators
    Patent number: 9179676
    Abstract: The invention relates to a carboxylic acid derivatives of benzoheterocyclyl pyridines and benzoheterocyclyl pyrimidines of general formula (I) and to the use thereof as herbicides.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: November 10, 2015
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Gerhard Hoffmann, Marco Brüenjes, Uwe Döller, Hans-Jörg Dietrich, Isolde Häeuser-Hahn, Christopher Hugh Rosinger, Elmar Gatzweiler, Ines Heinemann
  • HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES
    Publication number: 20150307470
    Abstract: There are described 6?-phenyl-2,2?-bipyridine-3-carboxylic acid derivatives of the general formula (I) as herbicides. In this formula (I), R1 to R5 are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen, nitro, cyano and formyl.
    Type: Application
    Filed: August 2, 2013
    Publication date: October 29, 2015
    Inventors: Michael Gerhard HOFFMANN, Uwe DOELLER, Marco BRUENJES, Hansjoerg DIETRICH, Elmar GATZWEILER, Christopher Hugh ROSINGER, Dirk SCHMUTZLER
  • HERBICIDALLY ACTIVE 2'-PHENYL-2,4'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES
    Publication number: 20150291553
    Abstract: 2?-Phenyl-2,4?-bipyridine-3-carboxylic acid derivatives of the general formula (I) are described as herbicides. In this formula (I), R1 to R5 are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen, nitro, cyano and formyl.
    Type: Application
    Filed: August 2, 2013
    Publication date: October 15, 2015
    Inventors: Michael Gerhard Hoffmann, Uwe Doeller, Marco Bruenjes, Hansjoerg Dietrich, Elmar Gatzweiler, Christopher Hugh Rosinger
  • 6-(2-aminophenyl)picolinates and their use as herbicides
    Patent number: 9078440
    Abstract: The present invention relates to novel herbicidally active 6-(2-aminophenyl)picoline derivatives and to processes for preparation thereof. The present invention further provides for the use thereof as a herbicide, especially as a herbicide for selective control of weed plants in useful plant crops, and as a plant growth regulator alone or in combination with safeners and/or in a mixture with other herbicides.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: July 14, 2015
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Marco Brünjes, Uwe Döller, Hansjörg Dietrich, Michael Gerhard Hoffmann, Isolde Häuser-Hahn, Christopher Hugh Rosinger, Elmar Gatzweiler, Ines Heinemann
  • Substituted picolinic acids, salts and acid derivatives thereof, and use thereof as herbicides
    Patent number: 8962529
    Abstract: The present invention relates to novel, herbicidally active picolinic acid derivatives of the formula (I) and to processes for preparation thereof. The present invention further provides for the use thereof as a herbicide, especially as a herbicide for selective control of weed plants in useful plant crops, and as a plant growth regulator alone or in combination with safeners and/or in a mixture with other herbicides.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: February 24, 2015
    Assignee: Bayer Cropscience AG
    Inventors: Harmut Ahrens, Marco Brünjes, Hansjörg Dietrich, Elmar Gatzweiler, Isolde Häuser-Hahn, Stefan Lehr, Dirk Schmutzler
  • SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS
    Publication number: 20150005165
    Abstract: The invention relates to a carboxylic acid derivatives of benzoheterocyclyl pyridines and benzoheterocyclyl pyrimidines of general formula (I) and to the use thereof as herbicides.
    Type: Application
    Filed: July 24, 2012
    Publication date: January 1, 2015
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Gerhard Hoffmann, Marco Bruenjes, Uwe Doeller, Hans-Joerg Dietrich, Isolde Haeuser-Hahn, Christopher Hugh Rosinger, Elmar Gatzweiler, Ines Heinemann
  • 6-(2-Aminophenyl)picolinates and their use as herbicides
    Publication number: 20130326735
    Abstract: The present invention relates to novel herbicidally active 6-(2-aminophenyl)picoline derivatives and to processes for preparation thereof. The present invention further provides for the use thereof as a herbicide, especially as a herbicide for selective control of weed plants in useful plant crops, and as a plant growth regulator alone or in combination with safeners and/or in a mixture with other herbicides.
    Type: Application
    Filed: December 12, 2011
    Publication date: December 5, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Marco Brünjes, Uwe Döller, Hansjörg Dietrich, Michael Gerhard Hoffmann, Isolde Häuser-Hahn, Christopher Hugh Rosinger, Elmar Gatzweiler, Ines Heinemann
  • Pyrimidin-4-ylpropanedinitrile derivatives, processes for their preparation and their use as herbicides and plant growth regulators
    Patent number: 8309557
    Abstract: The invention relates to compounds of the formula (I) and N-oxides, tautomers and agrochemically compatible salts thereof to processes for their preparation, and to their use as herbicides and plant growth regulators, in particular as herbicides for the selected control of harmful plants in useful plant crops.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: November 13, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Marco Brünjes, Hansjörg Dietrich, Hartmut Ahrens, Michael Gerhard Hoffmann, Jan Dittgen, Dieter Feucht, Christopher Hugh Rosinger, Isolde Häuser-Hahn