Abstract: Embodiments of the disclosure encompass systems, methods, and compositions related to selective advantages to somatic cells that harbor one or more particular genetic modifications. In particular embodiments, there is selective expansion of gene-targeted cells wherein the strategy involves deletion of an essential gene product that is replaced with targeted integration that also includes integration of a therapeutic transgene. The cells that harbor the replaced essential gene product, and thereby the therapeutic transgene, are selected for using pharmaceutical or nutritional agents that are linked to the function of the essential gene product.

Abstract: The present invention relates to a shielding system for conductor cables as well as to a method for producing said shielding system. The system is characterized in that it comprises a corrugated tube (20) coated with one or more thin films of high electrical conductivity material (30) which are reversibly adhered to the surface of said corrugated tube (20) so that said coating can be uncoupled from the corrugated tube due to high bending values of the tube itself. The shielding system according to the present invention therefore combines the excellent shielding efficacy values of a system having thin metal films with the excellent flexibility properties of a corrugated plastic tube.

Abstract: Gasket for refrigerator cabinets for providing seal-tight closure between cabinet (32) and door (17) composed of an outer door (30) and inner door (31), comprising a soft bellows portion (11), characterized in that said soft bellows portion (11) is interposed in an extensible manner between at least a pair of magnets (9, 15) one of which is operatively coupled to said door and the other is coupled to said cabinet.

Abstract: The present invention relates to a shielding system for conductor cables as well as to a method for producing said shielding system. The system is characterized in that it comprises a corrugated tube (20) coated with one or more thin films of high electrical conductivity material (30) which are reversibly adhered to the surface of said corrugated tube (20) so that said coating can be uncoupled from the corrugated tube due to high bending values of the tube itself. The shielding system according to the present invention therefore combines the excellent shielding efficacy values of a system having thin metal films with the excellent flexibility properties of a corrugated plastic tube.

Abstract: Gasket for refrigerator cabinets for providing seal-tight closure between cabinet (32) and door (17) composed of an outer door (30) and inner door (31), comprising a soft bellows portion (11), characterized in that said soft bellows portion (11) is interposed in an extensible manner between at least a pair of magnets (9, 15) one of which is operatively coupled to said door and the other is coupled to said cabinet.

Abstract: Gasket for refrigerator cabinets of the kind including a soft bellows-type portion used for sealing the area between the cabinet and the door and extending from a base portion able to match the outer door and/or inner door of the refrigerator cabinet. The base portion is substantially rigid and has at one end, a sealing portion made of substantially soft material extending toward the inner door. The soft material portion has good flexible and spring back features when exposed to refrigerator and freezer temperatures. These features make the gasket able to further seal, preferably by compression, the space located between the cabinet and inner door in a more internal area of the refrigerator cabinet. Furthermore, the soft sealing portion is independent and free from constraints with respect to the soft bellows-type portion.

Abstract: Gasket for refrigerator cabinets of the kind including a soft bellows-type portion used for sealing the area between the cabinet and the door, thus extending from a base portion able to match the outer door and/or inner door of the refrigerator cabinet, wherein said base portion is substantially rigid and that at one end of it there is a means made of substantially soft material extending toward said inner door, said material having good flexible and spring back features when exposed to refrigerator and freezer temperatures, able to further seal, preferably by compression, the space located between said cabinets and inner door in a more internal area of the refrigerator cabinet, wherein said sealing means is independent and free from constraints with respect to said soft bellows-type portion.

Abstract: A seal has a sealing action between a fixed part and a part which can be opened, in particular between the body and the door of a vehicle, of the type having a profiled element for fixing to the parts and a portion consisting of material which is deformable as a result of compression so as to provide operationally the sealing action, including at least two elements of magnetic material having surfaces with the same polarity are arranged in the region of the deformable portion, in a position facing each other.

Abstract: A glass-scraper seal used in windows which may be opened and are fitted with sliding glass, in particular for motor vehicles, with the glass-scraper seal having a portion capable of flexing elastically under the action of the glass so as to form a seal against a portion arranged opposite it, in each of the two opposite portions of the seal there being arranged at least one magnetic element, respectively, the surface of which facing that of the magnetic element of the opposite portion having an identical polarity such as to produce between them a repulsive magnetic force.

Abstract: The present invention relates to a synthetic leather free from halogens and prepared with a method characterized in that it comprises the following stages: a) forming, in a mould by means of slush moulding, a first layer, i.e. the visible layer in the finished leather, from a polyolefin composition grafted with silanes and cross-linkable in the presence of water, b) in immediate succession, forming, in said mould by means of slush moulding, a second layer from a polyolefin composition having a semi-crystalline phase with a high melting point not less than 120° C. and preferably not less than 140° C.

Abstract: New polyesters comprising polyoxyfluoroalkylene blocks are prepared by polycondensation of diols with dicarboxylic acids or with derivatives thereof, said fluorinated polyesters being characterized by such improved surface properties that any subsequent treatments of the surface of the articles obtained therefrom are needless.

Abstract: A non-fluorinated epoxy prepolymer of known type is mixed with a fluorinated epoxy prepolymer containing perfluoropolyether blocks or perfluoroalkylene blocks of type --(CF.sub.2 CF.sub.2).sub.n -- and/or of type ##STR1## and the two prepolymers are co-cured by treating the mixture with cross-linking agents of known type suitable for epoxy resins, thereby obtaining a cross-linked epoxy resin having a fluorine content.ltoreq.30% by weight, preferably.ltoreq.25% by weight.

Abstract: Fluorinated polyisocyanates particularly suitable for the formulation of coating paints and compositions in the electronics industry, obtained by starting from a perfluoropolyether polyol having a functionality higher than 2 and from a diisocyanate, the resulting derivative having isocyanic functions being further condensed with a polyol in order to obtain a polyisocyanate with a high degree of functionality, and containing from 1.5% to 9% by weight of --NCO groups.

Abstract: Non-fluorinated tertiary aminic compounds, comprising two or more functional groups containing at least three active H, of the hydroxyl or aminic or thiol type, are utilized, in the form of a homogeneous mixture with perfluoropolyethers having hydroxy end groups, to prepare by means of polycondensation and cross-linking reaction with fluorinated or non-fluorinated polyisocyanates, carried out in the absence of catalysts, the corresponding polymers containing the perfluoropolyethereal chain deriving from the perfluoropolyether having hydroxy end groups.