Abstract: The invention relates to a process for producing an energy-absorbing component composed of profile elements, made of a polymer material, which are open on one side, respectively orientated in opposite directions, and connected to one another on at least one side as a single piece to give a linearly continuous structure. The process involves (a) closure of a mold comprising at least two mold-section profiles, which can be moved in opposite directions and respectively have protruding regions and recessed regions such that, in a closed condition, the protruding regions of oppositely arranged profiles intermesh; (b) injection of the polymer material into a mold; and (c) opening of the mold, by moving the mold-section profiles apart in an opposite direction, and removing the energy-absorbing component.

Abstract: The invention relates to a novel GAFA domain-containing polypeptide, to the GAFA domain of a human phosphodiesterase 11 (PDE11) and to the adenylate cyclase catalytic domain. The use of said polypeptide in a method for identifying PDE-11 modulators is also disclosed.