Patents by Inventor Marco Maccarana

Marco Maccarana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody tools for the diagnostic use in the medical therapy with inhibitors of histone deacetylases
    Patent number: 7858329
    Abstract: The invention relates to a method for determining whether a treatment of a disorder with an HDAC inhibitor is to be started/continued or not comprising determining the level of histone acetylation in the sample by use of an antibody capable of binding to acetylated histone, and classifying the disorder as to be treated with an HDAC inhibitor when the level of histone acetylation is significantly lower than that of a reference sample. The invention further relates to the diagnostic and prognostic use of specific antibodies and cell lines producing them.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: December 28, 2010
    Assignee: TopoTarget Germany AG
    Inventors: Giuseppe Pier Pelicci, Saverio Minucci, Daniele Piccini, Marco Maccarana, Simona Ronzoni, Beatriz Liliana Areces, Mario Faretta
  • Antibody tools for the diagnostic use in the medical therapy with inhibitors of histone deacetylases
    Publication number: 20060257948
    Abstract: The invention relates to a method for determining whether a treatment of a disorder with an HDAC inhibitor is to be started/continued or not comprising determining the level of histone acetylation in the sample by use of an antibody capable of binding to acetylated histone, and classifying the disorder as to be treated with an HDAC inhibitor when the level of histone acetylation is significantly lower than that of a reference sample. The invention further relates to the diagnostic and prognostic use of specific antibodies and cell lines producing them.
    Type: Application
    Filed: September 30, 2003
    Publication date: November 16, 2006
    Applicant: G2M CANCER DRUGS AG
    Inventors: Pier Pelicci, Saverio Minucci, Daniele Piccini, Marco Maccarana, Simona Ronzoni, Beatriz Areces, Mario Faretta