Patents by Inventor Marco MARRADI

Marco MARRADI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANO-ANTIBIOTICS BASED ON SINGLE-CHAIN DEXTRAN NANOPARTICLES
    Publication number: 20220193256
    Abstract: The present invention relates to a water-dispersible single-chain dextran methacrylate or acrylate based nanoconjugate, which comprises a water-dispersible single-chain dextran methacrylate or acrylate based nanoparticle and one or more hydrophilic active ingredients, and having: a particle size from 3 nm to 50 nm, a zeta potential from ?25 mV to +20 mV, a percentage of intra-molecular crosslinking from 3% to 45% molar % of the total amount of monomer units present in the dextran methacrylate or acrylate chain, and a drug loading from 20% to 40% by weight of the drug in relation to the total weight of the nanoconjugate. It also relates to processes for their preparation, compositions containing them and their use in therapy.
    Type: Application
    Filed: April 17, 2020
    Publication date: June 23, 2022
    Inventors: Raquel GRACIA ESPAÑA, Julie MOVELLAN, Marco MARRADI, Damien DUPIN, lraida LOINAZ BORDONABE, Xabier MURGIA ESTEVE
  • Process for preparing water-dispersible single-chain polymeric nanoparticles
    Patent number: 10550205
    Abstract: The present invention comprises a process for preparing water-dispersible single-chain polymeric nanoparticles, which comprises cross-linking a polymer having a solubility equal to or higher than 100 mg per litre of water, and an amount of complementary reactive groups comprised from 5 to 60 molar % of the total amount of monomer units present in the polymer chain; with a crosslinking agent having crosslinkable groups; at a temperature comprised from 20 to 25° C. in the absence of a catalyst; to obtain water-dispersible conjugates and compositions containing the nanoparticle; and the use thereof.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: February 4, 2020
    Assignee: FUNDACIÓN CIDETEC
    Inventors: Miren Karmele Aiertza Otxotorena, Laura Sánchez Abella, Ana Belén Benito Collado, Iraida Loinaz Bordonabe, Germán Cabañero, Hans-Jürgen Grande, Marco Marradi, Raquel Gracia España
  • USE OF A GNP-LLO91-99 COMPLEX FOR THE TREATMENT AND PREVENTION OF CANCER
    Publication number: 20190046627
    Abstract: The present invention relates to the use of a GNP-LLO91-99 complex for providing immune responses for the treatment or prophylaxis of cancer.
    Type: Application
    Filed: February 23, 2017
    Publication date: February 14, 2019
    Inventors: Carmen ÁLVAREZ DOMÍNGUEZ, Ricardo CALDERÓN GONZÁLEZ, Elisabet FRANDE CABANES, Sonsoles YÁÑEZ DIAZ, Eva FERRÁNDEZ FERNÁNDEZ, Soledad PENADÉS ULLATE, Marco MARRADI, Isabel GARCÍA MARTÍN, Fernando RIVERA HERRERO
  • A PROCESS FOR PREPARING WATER-DISPERSIBLE SINGLE-CHAIN POLYMERIC NANOPARTICLES
    Publication number: 20170320974
    Abstract: The present invention comprises a process for preparing water-dispersible single-chain polymeric nanoparticles, which comprises cross-linking a polymer having a solubility equal to or higher than 100 mg per litre of water, and an amount of complementary reactive groups comprised from 5 to 60 molar % of the total amount of monomer units present in the polymer chain; with a crosslinking agent having crosslinkable groups; at a temperature comprised from 20 to 25° C. in the absence of a catalyst; to obtain water-dispersible conjugates and compositions containing the nanoparticle; and the use thereof.
    Type: Application
    Filed: November 2, 2015
    Publication date: November 9, 2017
    Applicant: FUNDACIÓN CIDETEC
    Inventors: Miren Karmele AIERTZA OTXOTORENA, Laura SÁNCHEZ ABELLA, Ana Belén BENITO COLLADO, Iraida LOINAZ BORDONABE, Germán CABAÑERO, Hans-Jürgen GRANDE, Marco MARRADI, Raquel GRACIA ESPAÑA