Patents by Inventor Marco Presta

Marco Presta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FGF2-binding peptides and uses thereof
    Patent number: 8076300
    Abstract: FGF2-binding peptides are here described, which have been designed starting from the N-terminal region of PTX3, in particular spanning the PTX3(82-11O) region. Synthetic peptides related to this sequence are able to bind FGF2 and to inhibit its pro-angiogenic activity in vitro and in vivo with no anticipated impact on innate immunity.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: December 13, 2011
    Assignee: Tecnogen S.p.A.
    Inventors: Marco Presta, Maura Camozzi, Marco Rusnati, Maurizio Colombo, Domenico Mastroianni
  • Use of the long pentraxin PTX3 for the treatment of diseases caused by an altered activation of the growth factor FGF-2
    Patent number: 7858577
    Abstract: The use of the long pentraxin PTX3 (PTX3) or one of its functional derivatives is described for the preparation of medicament which inhibits the biological activity of the growth factor FGF-2, useful for the prevention and treatment of diseases brought about by an altered activation of said growth factor FGF-2.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: December 28, 2010
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Alberto Mantovani, Barbara Bottazzi, Marco Presta, Marco Rusnati
  • FGF2-BINDING PEPTIDES AND USES THEREOF
    Publication number: 20090215689
    Abstract: FGF2-binding peptides are here described, which have been designed starting from the N-terminal region of PTX3, in particular spanning the PTX3(82-110) region. Synthetic peptides related to this sequence are able to bind FGF2 and to inhibit its pro-angiogenic activity in vitro and in vivo with no anticipated impact on innate immunity.
    Type: Application
    Filed: January 23, 2007
    Publication date: August 27, 2009
    Inventors: Marco Presta, Maura Camozzi, Marco Rusnati, Maurizio Colombo, Domenico Mastroianni
  • Use of long pentraxin ptx3 for the treatment of fgf-8 mediated tumour diseases
    Publication number: 20050043230
    Abstract: The use is described of the long pentraxin PTX3 (PTX3) or one of its functional derivatives as an agent inhibiting the activity of growth factor FGF-8, for the preparation of a medicine for the treatment of tumour diseases associated with abnormal activation of growth factor FGF-8.
    Type: Application
    Filed: April 4, 2003
    Publication date: February 24, 2005
    Inventors: Marco Presta, Marco Rusnati, Alberto Mantovani, Barbara Bottazzi
  • Use of the long pentraxin ptx3 for the treatment of diseases caused by an altered activation of the growth factor fgf-2
    Publication number: 20040023879
    Abstract: The use of the long pentraxin PTX3 (PTX3) or one of its functional derivatives is described for the preparation of medicament which inhibits the biological activity of the growth factor FGF-2, useful for the prevention and treatment of diseases brought about by an altered activation of said growth factor FGF-2.
    Type: Application
    Filed: August 28, 2003
    Publication date: February 5, 2004
    Inventors: Alberto Mantovani, Barbara Bottazzi, Marco Presta, Marco Rusnati