Abstract: A method for controlling an aircraft capable of hovering is described, comprising a first engine; a second engine; at least one rotor; and a transmission interposed between the first and second engine and the rotor; the transmission comprises a first and a second inlet connected respectively to a first outlet member of the first engine and to a second outlet member of the second engine; the method comprises step i) of placing the in a first configuration, in which the first and second engine make available a first and a second power value; or in a second configuration, in which the first engine (makes available a third power value greater than the first power value to the first inlet, and the second engine delivers a nil power value to the second inlet; the method also comprises, characterised in that it comprises the steps of ii) detecting a series of parameters associated with the operating conditions of the aircraft; and iii) enabling the transition of the aircraft from the first configuration to the secon

Abstract: The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid moiety, all covalently linked, which aggregate to synthetic virus-like particles. Proline-rich peptide antigens considered contain negatively and positively charged amino acid, and at least 15% of the amino acids are proline. Such synthetic virus-like particles carrying proline-rich antigens derived from pneumococcal proteins are useful as vaccines against infectious diseases caused by Gram-positive bacteria such as Streptococcus pneumoniae.

Abstract: The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid moiety, all covalently linked, which aggregate to synthetic virus-like particles. Proline-rich peptide antigens considered contain negatively and positively charged amino acid, and at least 15% of the amino acids are proline. Such synthetic virus-like particles carrying proline-rich antigens derived from pneumococcal proteins are useful as vaccines against infectious diseases caused by Gram-positive bacteria such as Streptococcus pneumoniae.