Patents by Inventor Marco Van Brussel
Marco Van Brussel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230340443Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and ?-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.Type: ApplicationFiled: January 6, 2023Publication date: October 26, 2023Inventors: Bart C. Koops, Paula Johanna Maria Teunissen, Marco Van Brussel-Zwijnen, Martijn Scheffers, Kees-Jan Guijt, Zhengzheng Zou, Zhongmei Tang, Zhen Qian, Jing Ge, Zhenghong Zhang
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Publication number: 20230055224Abstract: Disclosed are compositions and methods relating to an improved hybrid lipase enzyme for reducing foaming in, for example, a carbohydrate fermentation process.Type: ApplicationFiled: March 13, 2020Publication date: February 23, 2023Inventors: Sharief BARENDS, Svetlana Laura IANCU, Scott D. POWER, Marco VAN BRUSSEL-ZWIJNEN
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Publication number: 20220325211Abstract: Methods of using thermostable serine proteases are described herein.Type: ApplicationFiled: January 20, 2022Publication date: October 13, 2022Inventors: Jacob Flyvholm Cramer, Marc Anton Bernhard Kolkman, Zhen Ma, Martijn Scheffers, Stepan Shipovskov, Marco Van Brussel-Zwijnen, Shukun Yu
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Publication number: 20200063115Abstract: Methods of using archaeal serine protease sequences are disclosed.Type: ApplicationFiled: March 9, 2018Publication date: February 27, 2020Inventors: Xiaogang Gu, Zhengzheng Zou, Shukun Yu, Stepan Shipovskov, Marco Van Brussel-Zwijnen
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Publication number: 20190330577Abstract: Methods of using thermostable serine proteases are described herein.Type: ApplicationFiled: December 18, 2017Publication date: October 31, 2019Inventors: Jacob Flyvholm Cramer, Marc Anton Bernhard Kolkman, Zhen Ma, Martijn Scheffers, Stepan Shipovskov, Marco Van Brussel-Zwijnen, Shukun Yu
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Publication number: 20190010473Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and ?-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.Type: ApplicationFiled: December 20, 2016Publication date: January 10, 2019Inventors: Bart C. Koops, Paula Johanna Maria Teunissen, Marco Van Brussel-Zwijnen, Martijn Scheffers, Kees-Jan Guijt, Zhengzheng Zou, Zhongmei Tang, Zhen Qian, Jing Ge, Zhenghong Zhang
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Publication number: 20190002854Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and ?-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.Type: ApplicationFiled: December 20, 2016Publication date: January 3, 2019Inventors: Bart C. Koops, Paula Johanna Maria Teunissen, Marco Van Brussel-Zwijnen, Martijn Scheffers, Kees-Jan Guijt, Zhengzheng Zou, Zhongmei Tang, Zhen Qian, Jing Ge, Zhenghong Zhang
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Publication number: 20190002937Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and ?-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.Type: ApplicationFiled: December 20, 2016Publication date: January 3, 2019Inventors: Bart C. Koops, Paula Johanna Maria Teunissen, Marco Van Brussel-Zwijnen, Martijn Scheffers, Kees-Jan Guijt, Zhengzheng Zou, Zhongmei Tang, Zhen Qian, Jing Ge, Zhenghong Zhang
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Patent number: 9765374Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmyl). AfAmyl has an optimal pH of 3.5 and is operable at 30-75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DPI+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: GrantFiled: December 5, 2013Date of Patent: September 19, 2017Assignee: DANISCO US INCInventors: Ling Hua, Martijn Scheffers, Marco Van Brussel, Casper Vroemen, Bo Zhang, Zhengong Zhang
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Patent number: 9365871Abstract: A fungal ?-amylase is provided from Aspergillus clavatus (AcAmy1). AcAmy1 has an optimal pH of 4.5 and is operable at 30-75° C., allowing the enzyme to be used in combination with a glucoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the ?-amylase or glucoamylase. AcAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an ?-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: GrantFiled: December 4, 2014Date of Patent: June 14, 2016Assignee: Danisco US Inc.Inventors: Jing Ge, Ling Hua, Martijn Silvan Scheffers, Zhongmei Tang, Marco Van Brussel-Zwijnen, Casper Vroemen, Bo Zhang, Kathleen A. Clarkson, Jacquelyn A. Huitink, Paula Johanna Maria Teunissen
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Publication number: 20160040202Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmy1). AfAmy1 has an optimal pH of 3.5 and is operable at 30-75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and a pullulanase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: December 5, 2013Publication date: February 11, 2016Inventors: Ling Hua, Martijn Scheffers, Marco Van Brussel, Casper Vroemen, Bo Zhang, Zhenghong Zhang
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Publication number: 20160032338Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmyl). AfAmyl has an optimal pH of 3.5 and is operable at 30-75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DPI+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: December 5, 2013Publication date: February 4, 2016Inventors: Ling Hua, Martijn Scheffers, Marco Van Brussel, Casper Vroemen, Bo Zhang, Zhengong Zhang
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Publication number: 20160010128Abstract: A fungal alpha-amylase is provided from Aspergillus terreus (AtAmyl). AtAmyl has an optimal pH of 4.5 and is operable at 30 75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and a pullulanase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AtAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: December 6, 2013Publication date: January 14, 2016Applicant: Danisco US Inc.Inventors: Jing Ge, Ling Hua, Martijn Scheffers, Marco Van Brussel, Casper Vroemen, Bo Zhang
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Publication number: 20150376668Abstract: A fungal alpha-amylase is provided from Aspergillus terreus (AtAmy1). AtAmy1 has an optimal pH of 4.5 and is operable at 30 75 degrees C., allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AtAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an alpha amylase from Aspergillus kawachii. This facilitates the utilization of the ligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: December 6, 2013Publication date: December 31, 2015Inventors: Jing Ge, Ling Hua, Martijn Scheffers, Marco Van Brussel, Casper Vroemen, Bo Zhang
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Publication number: 20150232901Abstract: A fungal alpha-amylase is provided from Aspergillus clavatus (AcAmy1). AcAmy1 has an optimal pH of 4.5 and is operable at 30-75° C., allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AcAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: August 13, 2013Publication date: August 20, 2015Inventors: Marco van Brussel-Zwijnen, Martijn Silvan Scheffers, Casper Vroemen
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Publication number: 20150218606Abstract: A fungal alpha amylase is provided from Aspergillus clavatus (AcAmyl). AcAmyl has an optimal pH of 4.5 and is operable at 30-75 C, allowing the enzyme to be used in combination with a glucoamylase and a pullulanase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha amylase or glucoamylase. AcAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an alpha amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: August 13, 2013Publication date: August 6, 2015Inventors: Marco van Brussel-Zwijnen, Jacquelyn A. Huitink, Martijn Silvan Scheffers, Paula Johanna Maria Teunissen, Casper Vroemen
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Publication number: 20150152442Abstract: A fungal ?-amylase is provided from Aspergillus clavatus (AcAmy1). AcAmy1 has an optimal pH of 4.5 and is operable at 30-75° C., allowing the enzyme to be used in combination with a glucoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the ?-amylase or glucoamylase. AcAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an ?-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: December 4, 2014Publication date: June 4, 2015Inventors: Jing Ge, Ling Hua, Martijn Silvan Scheffers, Zhongmei Tang, Marco Van Brussel-Zwijnen, Casper Vroemen, Bo Zhang, Kathleen A. Clarkson, Jacquelyn A. Huitink, Paula Johanna Maria Teunissen
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Patent number: 8945889Abstract: A fungal ?-amylase is provided from Aspergillus clavatus (AcAmyl). AcAmyl has an optimal pH of 4.5 and is operable at 30-75° C., allowing the enzyme to be used in combination with a glucoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the ?-amylase or glucoamylase. AcAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an ?-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: GrantFiled: May 6, 2013Date of Patent: February 3, 2015Assignee: Danisco US Inc.Inventors: Jing Ge, Ling Hua, Martijn Silvan Scheffers, Zhongmei Tang, Marco Van Brussel-Zwijnen, Casper Vroemen, Bo Zhang, Kathleen A. Clarkson, Jacquelyn A. Huitink, Paula Johanna Maria Teunissen
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Publication number: 20130323798Abstract: A fungal ?-amylase is provided from Aspergillus clavatus (AcAmyl). AcAmyl has an optimal pH of 4.5 and is operable at 30-75° C., allowing the enzyme to be used in combination with a glucoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the ?-amylase or glucoamylase. AcAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an ?-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.Type: ApplicationFiled: May 6, 2013Publication date: December 5, 2013Applicant: Danisco US Inc.Inventors: Jing Ge, Ling Hua, Martijn Silvan Scheffers, Zhongmei Tang, Marco Van Brussel-Zwijnen, Casper Vroemen, Bo Zhang, Kathleen A. Clarkson, Jacquelyn A. Huitink, Paula Johanna Maria Teunissen