Abstract: An exemplary system, method and computer-accessible medium for determining a location a radioactive seed(s) within a body, can include, for example receiving first imaging information of the radioactive seed(s) within the body based on a first imaging modality, receiving second imaging information of the radioactive seed(s) within the body based on a second imaging modality, and determining the location of the radioactive seed(s) within the body based on the first and second imaging information. The first imaging modality can be computed tomography, and the second imaging modality can be an ultrasound, which can be a transrectal ultrasound. Third information related to a seed implantation plan for a patient(s) can be received.

Abstract: A method for treating a prostate gland comprises the steps of implanting therapeutic seeds in the prostate gland of a patient; imaging the implanted seeds with an imaging probe; calculating the three-dimensional locations of the implanted seeds and measuring the dosimetry of the implanted seeds; calculating optimal locations for additional seeds to provide an optimal post-implant dosimetric measurement; and implanting additional seeds in the optimal locations. The method may implement computer hardware and software.