Patents by Inventor Marcos Lopez
Marcos Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20190294749Abstract: According to exemplary embodiments, a system and method for automated system power supply design is provided. The system and method enables circuit designers to quickly and independently design complicated single or multi rail power supply systems including multiple loads and sequencing requirements. The power solutions offered to designers may include all required power supplies to power up the loads including sequencers and load switches. The power supply design system may be implemented on a standalone processing unit, a distributed computing network, internet based web application, or among various other network applications.Type: ApplicationFiled: June 13, 2019Publication date: September 26, 2019Inventors: Satyanandakishore Venkata Vanapalli, Abishek Gupta, Dien Mac, Andres Preciado, Pavani Jella, Wanda Carol Garrett, Marcos Lopez, Tim Reyes
-
Publication number: 20190294990Abstract: A method of estimating whether a statistical model is a false positive, comprising receiving a plurality of predicted outcomes computed by a plurality of statistical models for a historical dataset, computing a correlation matrix for the plurality of predicted outcomes, clustering the plurality of predicted outcomes in a plurality of clusters according to a plurality of clustering schemes based on the correlation matrix, selecting a clustering scheme having a highest quality score among a plurality of clustering schemes, computing, for each of the clusters of the selected clustering scheme, an aggregated predicted outcome aggregating the predicted outcomes clustered in the respective cluster, computing an estimated variance across the clusters, and computing a false positive probability of a selected one of the plurality of statistical models based on the aggregated predicted outcome of the cluster comprising the selected statistical model, the number of clusters, and the estimated variance across all clusterType: ApplicationFiled: March 20, 2019Publication date: September 26, 2019Inventor: Marcos LOPEZ DE PRADO
-
Patent number: 10366193Abstract: According to exemplary embodiments, a system and method for automated system power supply design is provided. The system and method enables circuit designers to quickly and independently design complicated single or multi rail power supply systems including multiple loads and sequencing requirements. The power solutions offered to designers may include all required power supplies to power up the loads including sequencers and load switches. The power supply design system may be implemented on a standalone processing unit, a distributed computing network, internet based web application, or among various other network applications.Type: GrantFiled: June 15, 2016Date of Patent: July 30, 2019Assignee: TEXAS INSTRUMENTS INCORPORATEDInventors: Satyanandakishore Venkata Vanapalli, Abishek Gupta, Dien Mac, Andres Preciado, Pavani Jella, Wanda Carol Garrett, Marcos Lopez, Tim Reyes
-
Publication number: 20190127066Abstract: A remote-controlled unmanned foldable aircraft comprises at least two motors that allow the aircraft to fly, and at least one support structure for supporting said motors; the support structure is flexible and inflatable such that the support structure can be folded and unfolded between a storage position and an operational position.Type: ApplicationFiled: February 28, 2017Publication date: May 2, 2019Inventors: Antoine Jacques Mistral Tournet, Roman Guillaume Jullen Ludani, Marco Lopez, Tom Patrick Lolies
-
Publication number: 20180309941Abstract: Systems and methods are disclosed for generating hyperspectral images, which may correspond to a three dimensional image in which two dimensions correspond to a spatial field of view and a third dimension corresponds to a frequency domain absorption spectrum. Disclosed systems and methods include those employing dual optical frequency comb Fourier transform spectroscopy and computational imaging for generation of hyperspectral images. Such a combination advantageously allows for imaging systems to exhibit low size, weight, and power, enabling small or handheld sized imaging devices.Type: ApplicationFiled: April 16, 2018Publication date: October 25, 2018Applicant: DRS Network & Imaging Systems, LLCInventors: Marco A. Lopez, Eden Y.C. Mei, Eric Anderson
-
Publication number: 20180186939Abstract: The present invention concerns a method for producing a hydrogel comprising the following steps in succession: a first step (i) of providing at least one powder of an anionic polymer (A) and at least one chitosan powder (B) comprising amine functions (—NH2); a second step (ii) consisting in dry mixing at least the powders (A) and (B) from the first step in order to form a mixture of powders; a third step (iii) of suspending the mixture of powders obtained from the second step in an aqueous medium having a pH that can enable the anionic polymer (A) to be dissolved without dissolving the chitosan (B); a fourth step (iv) of adding an acid to the suspension obtained from the third step in order to form the hydrogel; or the third (iii) and fourth (iv) steps are replaced by a mixing fifth step (v), comprising mixing an acidified aqueous medium including at least one compound (C) comprising at least one unit of a hexose or a unit derived from a hexose, and/or at least one phosphate of said compound (C), with saidType: ApplicationFiled: July 1, 2016Publication date: July 5, 2018Inventors: Nicolas BLANCHEMAIN, Bernard MARTEL, Claudia FLORES, Frédéric CAZAUX, Feng CHAI, Nicolas TABARY, Marco LOPEZ HEREDIA
-
Publication number: 20180182037Abstract: New computational technologies generating systematic investment portfolios by coordinating forecasting algorithms contributed by researchers are provided. Work on challenges is efficiently facilitated by the algorithmic developer's sandbox (“ADS”). Second, the algorithm selection system performs a batch of tests that selects the best developed algorithms, updates the list of open challenges and translates those scientific forecasts into financial predictions. The algorithm controls for the probability of backtest overfitting and selection bias, thus providing for a practical solution to a major flaw in computational research involving multiple testing. Third, the incubation system verifies the reliability of those selected algorithms. Fourth, the portfolio management system uses the selected algorithms to execute investment recommendations. A dynamically optimal portfolio trajectory is determined by a quantum computing solution to combinatorial optimization representation of the capital allocation problem.Type: ApplicationFiled: February 26, 2018Publication date: June 28, 2018Inventors: Jeffrey S. Lange, Marcos López De Prado
-
Publication number: 20180089762Abstract: Described herein are methods and system for generating a hierarchical data structure. A cluster of server computing devices receives a matrix of observations, derives a robust covariance matrix, and divides the matrix of observations into a plurality of computation tasks. Each processor in the cluster generates a first data structure for a distance matrix based upon a corresponding task, the distance matrix comprising a plurality of items, and clusters the items to generate a clustered distance matrix. Each processor generates a second data structure for a linkage matrix using the clustered matrix. Each processor reorganizes rows and columns of the linkage matrix to generate a quasi-diagonal matrix and recursively bisects the quasi-diagonal matrix. Each processor generates a third data structure containing the clusters and assigned weights. Each third data structure is consolidated into a solution vector, which is transmitted to a remote computing device.Type: ApplicationFiled: September 29, 2017Publication date: March 29, 2018Inventor: Marcos López de Prado
-
Publication number: 20170323206Abstract: A method and a system are disclosed for determining a weight allocation in a group comprising a large plurality of items using an optimization oracle, the method comprising obtaining an indication of a plurality of data for each item of a large plurality of items; generating a covariance matrix for the plurality of data; generating a hierarchical tree structure having a plurality of clusters, each cluster having a corresponding item associated therewith, the generating comprising until there is one item associated per cluster of the hierarchical tree structure, recursively formulating an optimization problem to divide a given set of items into two different clusters, translating the formulated optimization problem into an unconstrained binary optimization problem, providing an indication of the unconstrained binary optimization problem to an optimization oracle, receiving an indication of at least one solution from the optimization oracle, assigning a cluster to each item of the given set of items using the aType: ApplicationFiled: May 9, 2017Publication date: November 9, 2017Inventors: Elham ALIPOUR KHAYER, Arman ZARIBAFIYAN, Maxwell ROUNDS, Marcos LOPEZ DE PRADO, Clemens ADOLPHS
-
Publication number: 20170275313Abstract: The present invention provides mito-metformin compounds, pharmaceutical compositions thereof, and methods of using the mito-metformin compounds in the treatment of cancer.Type: ApplicationFiled: August 13, 2015Publication date: September 28, 2017Inventors: Balaraman Kalyanaramn, Micael J. Hardy, Marcos Lopez, Olivier Ouari, Jacek Michal Zielonka
-
Publication number: 20170185922Abstract: A cluster of server computing devices receives a matrix of observations and divides the matrix into a plurality of input data sets. Each processor in the cluster generates a first data structure for a distance matrix based upon a corresponding input data set, the distance matrix comprising a plurality of items, and clusters the items to generate a clustered distance matrix. Each processor generates a second data structure for a linkage matrix using the clustered matrix. Each processor analyzes the linkage matrix to determine a number of items per cluster and analyzes the linkage matrix to assign a weight to each cluster based upon a distance of the cluster to other clusters and a size of the cluster. Each processor generates a third data structure containing the clusters and assigned weights. Each third data structure is consolidated into a hierarchical data structure, which is transmitted to a remote computing device.Type: ApplicationFiled: December 27, 2016Publication date: June 29, 2017Inventors: Jeffrey S. Lange, Marcos López de Prado
-
Patent number: 9548498Abstract: The invention relates to a carbon-free electrocatalyst for fuel cells, containing an electrically conductive substrate and a catalytically active species, wherein the conductive substrate is an inorganic, multi-component substrate material of the composition 0X1-0X2, in which 0X1 means an electrically non-conductive inorganic oxide having a specific surface area (BET) in the range of 50 to 400 mVg and 0X2 means a conductive oxide. The non-conductive inorganic oxide 0X1 is coated with the conductive oxide 0X2. The multi-component substrate preferably has a core/shell structure. The multi-component substrate material 0X1-0X2 has an electrical conductivity in the range>0.01 S/cm and is coated with catalytically active particles containing noble metal. The electrocatalysts produced therewith are used in electrochemical devices such as PEM fuel cells and exhibit high corrosion stability.Type: GrantFiled: December 18, 2012Date of Patent: January 17, 2017Assignee: UMICORE AG & CO. KGInventors: Barbara Klose-Schubert, Daniel Herein, Marco Lopez, Carsten Becker
-
Publication number: 20160371415Abstract: According to exemplary embodiments, a system and method for automated system power supply design is provided. The system and method enables circuit designers to quickly and independently design complicated single or multi rail power supply systems including multiple loads and sequencing requirements. The power solutions offered to designers may include all required power supplies to power up the loads including sequencers and load switches. The power supply design system may be implemented on a standalone processing unit, a distributed computing network, internet based web application, or among various other network applications.Type: ApplicationFiled: June 15, 2016Publication date: December 22, 2016Applicant: Texas Instruments IncorporatedInventors: Satyanandakishore Venkata Vanapalli, Abishek Gupta, Dien Mac, Andres Preciado, Pavani Jella, Wanda Carol Garrett, Marcos Lopez, Tim Reyes
-
Patent number: 9463235Abstract: Vaccine compositions that comprise at least one antigen based on the dengue virus (DV) capsid protein and the oligonucleotide identified as SEQ ID NO 1. The vaccine composition that comprises a fusion protein formed by the DV2 capsid and domain III of the envelope protein of the same serotype, together with the oligonucleotide identified as SEQ ID NO 1, gives rise to higher levels of cellular immune response and protection in mice as compared with that produced by formulations of the same antigen together with oligonucleotides with potential adjuvant capacity which were reported previously. The efficacy of the compositions that comprise the SEQ ID NO 1 oligonucleotide has been demonstrated in non-human primates. These compositions may be monovalent, bivalent or tetravalent and are combined in different immunization regimes with a view to inducing a functional immune response to the four viral serotypes.Type: GrantFiled: December 16, 2013Date of Patent: October 11, 2016Assignee: CENTRO DE INGENIERÍA GENEÉTICA Y BIOTECHNOLOGÍAInventors: Lisset Hermida Cruz, Lázaro Gil González, Alienys Izquierdo Oliva, Ernesto Marcos López, Edith Suzarte Portal, Gerardo Enrique Guillén Nieto, María Guadalupe Guzmán Tirado, Iris Valdés Prado, Laura Lazo Vazquez, Angelica de la Caridad Garcia Arechavaleta, Mayling Alvarez Vera, Jorge Castro Velazco, Lázaro López Fernández, Rosa Liset Ramírez Bartutis, Yusleidi de la Caridad Pérez Fuentes, Olga Lidia Pérez Guevara, Yaremy Romero Fernández
-
Publication number: 20150328304Abstract: Vaccine compositions that comprise at least one antigen based on the dengue virus (DV) capsid protein and the oligonucleotide identified as SEQ ID NO 1. The vaccine composition that comprises a fusion protein formed by the DV2 capsid and domain III of the envelope protein of the same serotype, together with the oligonucleotide identified as SEQ ID NO 1, gives rise to higher levels of cellular immune response and protection in mice as compared with that produced by formulations of the same antigen together with oligonucleotides with potential adjuvant capacity which were reported previously. The efficacy of the compositions that comprise the SEQ ID NO 1 oligonucleotide has been demonstrated in non-human primates. These compositions may be monovalent, bivalent or tetravalent and are combined in different immunization regimes with a view to inducing a functional immune response to the four viral serotypes.Type: ApplicationFiled: December 16, 2013Publication date: November 19, 2015Inventors: Lisset Hermida Cruz, Lázaro Gil González, Alienys Izquierdo Oliva, Ernesto Marcos López, Edith Suzarte Portal, Gerardo Enrique Guillén Nieto, María Guadalupe Guzmán Tirado, Iris Valdés Prado, Laura Lazo Vazquez, Angelica de la Caridad García Arechavaleta, Mayling Alvarez Vera, Jorge Castro Velazco, Lázaro López Fernández, Rosa Liset Ramírez Bartutis, Yusleidi de la Caridad Pérez Fuentes, Olga Lidia Pérez Guevara, Yaremy Romero Fernández
-
Patent number: 9101915Abstract: The present invention is directed to catalyst particles comprising a layered core-shell-shell structure and to a method of their manufacture. The catalyst particles have the general formula BM/IL/PM in which BM is a base metal core (selected from Co, Ni or Cu), PM is a precious metal outer shell (selected from Pt, Ir or Pd) and IL is an intermediate layer comprising a base metal/precious metal alloy with a concentration gradient of base metal to the outside PM layer. The particles of the present invention comprise a core-shell-shell structure and a substantially continuous precious metal shell layer. They find use in various catalytic applications, for example in gas-phase catalysis, in electrocatalysts for fuel cells, in catalytic converters for automobiles and in electronic or medical applications.Type: GrantFiled: December 18, 2012Date of Patent: August 11, 2015Assignee: UMICORE AG & CO. KGInventors: Marco Lopez, Dan V. Goia, Igor V. Sevonkaev
-
Publication number: 20150206246Abstract: New computational technologies generating systematic investment portfolios by coordinating forecasting algorithms contributed by researchers are provided. Work on challenges is efficiently facilitated by the algorithmic developer's sandbox (“ADS”). Second, the algorithm selection system performs a batch of tests that selects the best developed algorithms, updates the list of open challenges and translates those scientific forecasts into financial predictions. The algorithm controls for the probability of backtest overfitting and selection bias, thus providing for a practical solution to a major flaw in computational research involving multiple testing. Third, the incubation system verifies the reliability of those selected algorithms. Fourth, the portfolio management system uses the selected algorithms to execute investment recommendations. A dynamically optimal portfolio trajectory is determined by a quantum computing solution to combinatorial optimization representation of the capital allocation problem.Type: ApplicationFiled: March 27, 2015Publication date: July 23, 2015Inventors: Jeffrey S. Lange, Marcos López de Prado
-
Publication number: 20140349203Abstract: The invention relates to a carbon-free electrocatalyst for fuel cells, containing an electrically conductive substrate and a catalytically active species, wherein the conductive substrate is an inorganic, multi-component substrate material of the composition 0X1-0X2, in which 0X1 means an electrically non-conductive inorganic oxide having a specific surface area (BET) in the range of 50 to 400 mVg and 0X2 means a conductive oxide. The non-conductive inorganic oxide 0X1 is coated with the conductive oxide 0X2. The multi-component substrate preferably has a core/shell structure. The multi-component substrate material 0X1-0X2 has an electrical conductivity in the range>0.01 S/cm and is coated with catalytically active particles containing noble metal. The electrocatalysts produced therewith are used in electrochemical devices such as PEM fuel cells and exhibit high corrosion stability.Type: ApplicationFiled: December 18, 2012Publication date: November 27, 2014Inventors: Barbara Klose-Schubert, Daniel Herein, Marco Lopez, Carsten Becker
-
Publication number: 20140171290Abstract: The present invention is directed to catalyst particles comprising a layered core-shell-shell structure and to a method of their manufacture. The catalyst particles have the general formula BM/IL/PM in which BM is a base metal core (selected from Co, Ni or Cu), PM is a precious metal outer shell (selected from Pt, Ir or Pd) and IL is an intermediate layer comprising a base metal/precious metal alloy with a concentration gradient of base metal to the outside PM layer. The particles of the present invention comprise a core-shell-shell structure and a substantially continuous precious metal shell layer. They find use in various catalytic applications, for example in gas-phase catalysis, in electrocatalysts for fuel cells, in catalytic converters for automobiles and in electronic or medical applications.Type: ApplicationFiled: December 18, 2012Publication date: June 19, 2014Applicant: UMICORE AG & CO. KGInventors: Marco LOPEZ, Dan V. GOIA, Igor V. SEVONKAEV
-
Patent number: 8691717Abstract: The invention discloses core/shell, type catalyst particles comprising a Mcore/Mshell structure with Mcore=inner particle core and Mshell=outer particle shell, wherein the medium diameter of the catalyst particle (dcore+shell) is in the range of 20 to 100 nm, preferably in the range of 20 to 50 nm. The thickness of the outer shell (tshell) is about 5 to 20% of the diameter of the inner particle core of said catalyst particle, preferably comprising at least 3 atomic layers. The core/shell type catalyst particles, particularly the particles comprising a Pt˜based shell reveal a high specific activity. The catalyst particles are preferably supported on suitable support materials such as carbon black and are used as electrocatalysts for fuel cells.Type: GrantFiled: July 24, 2012Date of Patent: April 8, 2014Assignee: Umicore AG & Co. KGInventors: Marco Lopez, Michael Lennartz, Dan V. Goia, Carsten Becker, Stéphanie Chevalliot