Patents by Inventor Marcos SIXTO

Marcos SIXTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-pulse transfection methods and cells
    Patent number: 11939585
    Abstract: Systems and methods are provided for transfecting immune competent cells with RNA at high efficiency and viability.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: March 26, 2024
    Assignee: NantBio, Inc.
    Inventors: Marcos Sixto, Kayvan Niazi, Ting Wu, Chihwei Chang
  • Multi-Pulse Transfection Methods And Cells
    Publication number: 20200318126
    Abstract: Systems and methods are provided for transfecting immune competent cells with RNA at high efficiency and viability.
    Type: Application
    Filed: June 17, 2020
    Publication date: October 8, 2020
    Inventors: Marcos SIXTO, Kayvan NIAZI, Ting WU, Chihwei CHANG
  • Lipid-Based Antigens and T-Cell Receptors on NK Cells
    Publication number: 20200283531
    Abstract: Compositions, methods and uses of genetically modified NK cells to elicit immune response against cells infected with microorganisms are presented. In some embodiments, NK cells can be genetically modified with a recombinant nucleic acid that includes a segment encoding an extracellular single-chain variant fragment that specifically binds a CD1-lipid antigen complex and another segment encoding an intracellular activation domain, and a linker between those segments. In other embodiments, the NK cells can be genetically modified with a recombinant nucleic acid that includes a segment encoding an a chain T cell receptor and a ? chain T cell receptor, and another segment encoding at least a portion of CD3? and at least a portion of CD3?. The genetically modified NK cells can be administered to the patient infected with microorganism to trigger immune response specific to the cells infected with the microorganism.
    Type: Application
    Filed: October 4, 2018
    Publication date: September 10, 2020
    Inventors: Kayvan Niazi, Marcos Sixto, Annie Shin, Phil Liu
  • Multi-pulse transfection methods and cells
    Patent number: 10724043
    Abstract: Systems and methods are provided for transfecting immune competent cells with RNA at high efficiency and viability.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: July 28, 2020
    Assignee: NantBio, Inc.
    Inventors: Marcos Sixto, Kayvan Niazi, Ting Wu, Chihwei Chang
  • MULTI-PULSE TRANSFECTION METHODS AND CELLS
    Publication number: 20180100161
    Abstract: Systems and methods are provided for transfecting immune competent cells with RNA at high efficiency and viability.
    Type: Application
    Filed: October 6, 2017
    Publication date: April 12, 2018
    Inventors: Marcos SIXTO, Kayvan NIAZI, Ting WU, Chihwei CHANG