Abstract: A method and kit for the classification of thyroid nodules that allows a more precise identification of the type of thyroid nodule as being malignant, benign or subclassifications, including at least one step of measuring the expression level of at least one normalizing microRNA and at least one discriminating microRNA and at least one step of correlation between the expression level of at least one normalizing microRNA and at least one discriminating microRNA.

Abstract: The present invention refers to a process for classifying tumor samples of unknown and/or uncertain primary origin, specifically including the steps of obtaining patterns of biological activity modulation of tumor of unknown and/or uncertain primary origin and comparing them to an specific and unique group of biomarkers which determine the profiles of biological activity modulation of known origin tumors. The present invention belongs to the molecular biology and genetics field.

Abstract: The present invention discloses a method for complete tracking of a set of biological samples containing DNA or RNA through the use of molecular barcode identification during the course of laboratorial workflow, wherein the sample is contacted with primers comprising a molecular barcode and a universal primer sequence immediately after its collection and the amplification of the target regions occurs concomitantly to the barcode insertion, in one or both ends of said target region, in the same annealing temperature through a one step PCR. Finally, the invention also discloses kits for collecting biological samples containing DNA or RNA.