Patents by Inventor Marcus Altfeld

Marcus Altfeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soluble virus-specific T-cell receptor compositions
    Publication number: 20080015139
    Abstract: Compositions and methods for diagnosing a viral infection and methods of inhibiting such an infection are described. The methods are based on the identification of T-cell receptor gene sequences from cytotoxic T cell clones that are specific for HIV-1 or HCV. Soluble T-cell receptor compositions that bind to HLA class I-restricted of HIV and HCV pathogens were identified and constructed.
    Type: Application
    Filed: April 5, 2007
    Publication date: January 17, 2008
    Inventors: Mathias Lichterfeld, Xu Yu, Bruce Walker, Marcus Altfeld, Georg Lauer
  • Epitopes of human immunodeficiency virus-1
    Publication number: 20060216306
    Abstract: The invention features an immunogenic composition containing a frequently-recognized epitope of an HIV-1 accessory protein and methods of inducing an immune response using such an epitope. The epitope peptide contains an amino acid sequence of a functionally active domain or a structural domain of the accessory protein.
    Type: Application
    Filed: December 12, 2005
    Publication date: September 28, 2006
    Inventors: Bruce Walker, Marcus Altfeld
  • Methods of inducing an HIV specific response using a Vpr-specific epitope
    Patent number: 6974574
    Abstract: The invention features an immunogenic composition containing a frequently-recognized epitope of an HIV-1 accessory protein such as Vpr and methods of inducing an immune response using such an epitope. The epitope peptide contains the amino acid sequence ALIRILQQL of a functionally active domain or a structural domain of the accessory protein.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: December 13, 2005
    Assignee: The General Hospital Corporation
    Inventors: Bruce D. Walker, Marcus Altfeld
  • Cytotoxic T-cell epitopes of HIV-1 virus
    Publication number: 20040001845
    Abstract: The invention provides compositions containing HIV epitopes, which are recognized by cytotoxic T lymphocytes (CTL). Such polypeptides are used in vaccines and immunotherapies. HIV-1 epitopes represent early targets in a naturally-occurring response against HIV-1 infection.
    Type: Application
    Filed: May 20, 2003
    Publication date: January 1, 2004
    Inventors: Marcus Altfeld, Xu Yu, Bruce D. Walker, Marylyn Addo
  • Epitopes of human immunodeficiency virus-1
    Publication number: 20030219450
    Abstract: The invention features an immunogenic composition containing a frequently-recognized epitope of an HIV-1 accessory protein and methods of inducing an immune response using such an epitope. The epitope peptide contains an amino acid sequence of a functionally active domain or a structural domain of the accessory protein.
    Type: Application
    Filed: August 16, 2002
    Publication date: November 27, 2003
    Inventors: Bruce D. Walker, Marcus Altfeld