Patents by Inventor Marcus D. Collins

Marcus D. Collins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analyte sequencing with nanopores
    Patent number: 11913905
    Abstract: Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
    Type: Grant
    Filed: November 24, 2021
    Date of Patent: February 27, 2024
    Assignee: University of Washington
    Inventors: Jens H. Gundlach, Ian M. Derrington, Marcus D. Collins
  • ANALYTE SEQUENCING WITH NANOPORES
    Publication number: 20220164126
    Abstract: Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
    Type: Application
    Filed: November 24, 2021
    Publication date: May 26, 2022
    Applicant: University of Washington
    Inventors: Jens H. Gundlach, Ian M. Derrington, Marcus D. Collins
  • Analyte sequencing with nanopores
    Patent number: 11187675
    Abstract: Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: November 30, 2021
    Assignee: University of Washington
    Inventors: Jens H. Gundlach, Ian M. Derrington, Marcus D. Collins
  • ANALYTE SEQUENCING WITH NANOPORES
    Publication number: 20170227494
    Abstract: Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
    Type: Application
    Filed: February 14, 2017
    Publication date: August 10, 2017
    Applicant: University of Washington
    Inventors: Jens H. Gundlach, Ian M. Derrington, Marcus D. Collins
  • Analyte sequencing with nanopores
    Patent number: 9588079
    Abstract: Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: March 7, 2017
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Jens Gundlach, Ian M. Derrington, Marcus D. Collins
  • ANALYTE SEQUENCING WITH NANOPORES
    Publication number: 20130146457
    Abstract: Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed.
    Type: Application
    Filed: August 22, 2012
    Publication date: June 13, 2013
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Jens Gundlach, Ian M. Derrington, Marcus D. Collins