Patents by Inventor Marcus Eli Brewster

Marcus Eli Brewster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions comprising a basic drug compound, a surfactant, and a physiologically tolerable water soluble acid
    Patent number: 9192577
    Abstract: The invention provides a novel pharmaceutical composition comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base characterized in that the acid respectively base:drug compound ratio is at least 1:1 by weight.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: November 24, 2015
    Assignee: Janssen Pharmaceutica NV
    Inventors: Roger Petrus Gerebern Vandecruys, Jozef Peeters, Marcus Eli Brewster
  • POLYMERIC MICROEMULSIONS
    Publication number: 20150086504
    Abstract: The invention provides novel self-emulsifying diblock copolymers and novel self-emulsifying compositions comprising an active ingredient and a diblock copolymer characterized in that the diblock copolymer is liquid at a temperature below 50° C. and the composition is non-aqueous and liquid at a temperature below 50° C.
    Type: Application
    Filed: December 1, 2014
    Publication date: March 26, 2015
    Inventors: Albertina Maria Eduarda Ariën, Marcus Eli Brewster, Aruna Nathan, Joel Rosenblatt, Louisa Myriam Ould-Ouali, Véronique Préat
  • POLYMERIC MICROEMULSIONS
    Publication number: 20110112115
    Abstract: The invention provides novel self-emulsifying diblock copolymers and novel self-emulsifying compositions comprising an active ingredient and a diblock copolymer characterized in that the diblock copolymer is liquid at a temperature below 50° C. and the composition is non-aqueous and liquid at a temperature below 50° C.
    Type: Application
    Filed: January 6, 2011
    Publication date: May 12, 2011
    Inventors: Albertina Maria Eduarda Ariën, Marcus Eli Brewster, Aruna Nathan, Joel Rosenblatt, Louisa Myriam Ould-Ouali, Véronique Preat
  • MODIFIED POLY(PROPYLENE-IMINE) DENDRIMERS AND THEIR USE AS TRANSFECTION AGENTS FOR AMIONIC BIOACTIVE FACTORS ( as amended
    Publication number: 20100298403
    Abstract: The present invention is concerned with modified poly-(propylene imine) dendrimers, comprising cationic internal ammonium groups and external non-toxic endgroups, pharmaceutical compositions comprising said dendrimers, methods for the production of said dendrimers and their use as transfections agents for anionic bioactive therapeutic factors, for use in gene therapy, in particular for the treatment of cancer. The modified poly-(propylene imine) dendrimer of generation 1, 2, 3, 4 or 5, also comprising incomplete dendrimers and mixtures thereof, comprising external end groups and internal amine functions are characterized in that: (a) substantially all external endgroups are groups of formula (I) ?wherein R is a radical selected from the group of C1-10alkyl, polyethylene glycol radical and polyethylene glycol gallyl radical; and (b) substantially all internal amine functions are quaternary cationic ammonium functions.
    Type: Application
    Filed: July 5, 2006
    Publication date: November 25, 2010
    Applicant: JANSSEN PHARMACEUTICA N.V.
    Inventors: Frederik Tack, Henricus Marie Janssen, Egbert Willem Meijer, Michel Marie Francois Janicot, Marcus Eli Brewster
  • Solid dispersions comprising two different polymer matrixes
    Patent number: 7407670
    Abstract: Present invention provides solid dispersions comprising a poorly soluble bioactive compound dispersed in a polymer matrix characterized in that the polymer matrix comprises more than one polymer. Said solid dispersions effectively stabilize the dispersed compound while stimulating the solubilisation of the compound in an aquaeous environment.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: August 5, 2008
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Karel Six, Geert Verreck, Jozef Peeters, Marcus Eli Brewster, Guy Van Den Mooter