Patents by Inventor Marcus J.C. LONG

Marcus J.C. LONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of genome-wide direct identification of electrophile-sensing targets
    Patent number: 11506670
    Abstract: The present invention relates to a method for identifying endogenous first responder protein-cysteines. Methods for screening candidate compounds suitable for regulating NF-kB signaling and the DNA damage response pathway are also disclosed.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: November 22, 2022
    Assignee: CORNELL UNIVERSITY
    Inventors: Yimon Aye, Marcus J. C. Long, Yi Zhao
  • AKT ISOZYME-SPECIFIC COVALENT INHIBITORS DERIVED FROM REDOX-SIGNALING LIPIDS
    Publication number: 20200148682
    Abstract: The present invention is directed to a compound of Formula (I) wherein A, X, Y, R1, R2, R3, R4, and n are as described herein. The present invention also relates to: 1) a method of treating cancer using a compound of Formula (I) and 2) a method of inhibiting pan-Akt in a cell or a tissue using a compound of Formula (I).
    Type: Application
    Filed: June 6, 2018
    Publication date: May 14, 2020
    Inventors: Yimon AYE, Xuyu LIU, Marcus J.C. LONG
  • METHOD OF GENOME-WIDE DIRECT IDENTIFICATION OF ELECTROPHILE-SENSING TARGETS
    Publication number: 20190265250
    Abstract: The present invention relates to a method for identifying endogenous first responder protein-cysteines. Methods for screening candidate compounds suitable for regulating NF-kB signaling and the DNA damage response pathway are also disclosed.
    Type: Application
    Filed: February 23, 2018
    Publication date: August 29, 2019
    Inventors: Yimon AYE, Marcus J.C. LONG, Yi ZHAO