Patents by Inventor Marcus KARLSTETTER

Marcus KARLSTETTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF IL-11 OR IL-11Ra FOR USE IN THE TREATMENT OF ABNORMAL UTERINE BLEEDING
    Publication number: 20240124572
    Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.
    Type: Application
    Filed: February 24, 2022
    Publication date: April 18, 2024
    Inventors: Maik Stefan Wilhelm OBENDORF, Frank SACHER, Jörg MÜLLER, Ralf LESCHE, Christian VOTSMEIER, Stephan MÄRSCH, Jan TEBBE, Philipp ELLINGER, Patrick Michael SMITH, Jenny FITTING, Katharina FILARSKY, Mathias GEHRMANN, Marcus KARLSTETTER, Ernst WEBER, Mark TRAUTWEIN
  • Polysialic acid and use for treatment of neurodegenerative and neuroinflammatory diseases
    Patent number: 9944721
    Abstract: The present invention relates to a branched or unbranched free or glycosidically bound polysialic acid according to general formula (1) as given as follows poly-(?(2?8 or 2?9)Neu5Ac)n (1) wherein Neu5Ac is N-acetylneuraminic acid, and n is an integer in the range from 14 to 26 and/or pharmaceutically acceptable salts thereof, a polysaccharide composition comprising the polysialic acid (1), and the use as a medicament, particularly in the therapeutic and/or prophylactic treatment of degenerative, demyelinating and inflammatory diseases of the central nervous system, and degenerative or inflammatory retinal diseases.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: April 17, 2018
    Assignees: RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN, UNIVERSITÄT ZU KÖLN
    Inventors: Harald Neumann, Jens Kopatz, Anahita Shahraz, Marcus Karlstetter, Thomas Langmann
  • Polysialic acid and use for treatment of neurodegenerative and neuroinflammatory diseases
    Publication number: 20160046734
    Abstract: The present invention relates to a branched or unbranched free or glycosidically bound polysialic acid according to general formula (1) as given as follows poly-(?(2?8 or 2?9)Neu5Ac)n (1) wherein Neu5Ac is N-acetylneuraminic acid, and n is an integer in the range from 14 to 26 and/or pharmaceutically acceptable salts thereof, a polysaccharide composition comprising the polysialic acid (1), and the use as a medicament, particularly in the therapeutic and/or prophylactic treatment of degenerative, demyelinating and inflammatory diseases of the central nervous system, and degenerative or inflammatory retinal diseases.
    Type: Application
    Filed: March 18, 2014
    Publication date: February 18, 2016
    Inventors: Harald NEUMANN, Jens KOPATZ, Anahita Shahraz, Marcus KARLSTETTER, Thomas LANGMANN