Patents by Inventor Marcus Knell
Marcus Knell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11964102Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.Type: GrantFiled: October 29, 2020Date of Patent: April 23, 2024Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Patent number: 11679212Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.Type: GrantFiled: August 13, 2018Date of Patent: June 20, 2023Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Publication number: 20210107874Abstract: The present invention is directed to a salt of a compound of formula (I), R1 is halogen or methyl; X is methyl, OR2, or SR2; Y1, Y2 is CR3 or N, and one of Y1, Y2 is N and one of Y1, Y2 is CR3; R2 is methyl or ethyl; R3 is hydrogen or methyl, wherein the salt is chosen from the group 10 consisting of malate salt, citrate salt, tartrate salt, oxalate salt, fumarate salt, lactate salt, glucoronate salt, oxoglucoronate salt, ethanesulfonate salt, and succinate salt. The present invention is further related to a pharmaceutical formulation comprising the salt of the invention wherein the base compound is present in an amount of 2-30% (w/v) and having a pH value of at least 3.7 and to methods of treatment using the salt of the invention.Type: ApplicationFiled: March 30, 2018Publication date: April 15, 2021Applicant: Intervet Inc.Inventors: Michael Berger, Hans Peter Niedermann, Marcus Knell, Anne Lehay, Angelique Duval, Anne-Laure Morer, Susi Alteheld
-
Publication number: 20210038837Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.Type: ApplicationFiled: October 29, 2020Publication date: February 11, 2021Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Patent number: 10869975Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.Type: GrantFiled: June 19, 2017Date of Patent: December 22, 2020Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Publication number: 20200353188Abstract: An inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.Type: ApplicationFiled: July 28, 2020Publication date: November 12, 2020Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Guido Endert, Horst Wergen
-
Publication number: 20200283389Abstract: An improved process for producing a compound of Formula (I).Type: ApplicationFiled: December 22, 2016Publication date: September 10, 2020Applicant: Intervet Inc.Inventors: Michael Berger, Hans Peter Niedermann, Tobias Kappesser, Stephan Veit, Heiko Bothe, Marcus Knell, Christophe Pierre Alain Chassaing
-
Patent number: 10737046Abstract: An inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.Type: GrantFiled: February 6, 2018Date of Patent: August 11, 2020Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Marcus Knell, Guido Endert, Horst Wergen
-
Publication number: 20180361088Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.Type: ApplicationFiled: August 13, 2018Publication date: December 20, 2018Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Patent number: 10046124Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.Type: GrantFiled: August 19, 2014Date of Patent: August 14, 2018Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Publication number: 20180161528Abstract: An inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.Type: ApplicationFiled: February 6, 2018Publication date: June 14, 2018Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Guido Endert, Horst Wergen
-
Patent number: 9913952Abstract: This invention relates to an inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.Type: GrantFiled: August 19, 2014Date of Patent: March 13, 2018Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Guido Endert, Horst Wergen
-
Publication number: 20170281886Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.Type: ApplicationFiled: June 19, 2017Publication date: October 5, 2017Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Patent number: 9713516Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.Type: GrantFiled: August 19, 2014Date of Patent: July 25, 2017Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Publication number: 20150053207Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.Type: ApplicationFiled: August 19, 2014Publication date: February 26, 2015Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Publication number: 20150053202Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.Type: ApplicationFiled: August 19, 2014Publication date: February 26, 2015Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
-
Publication number: 20150053203Abstract: This invention relates to an inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.Type: ApplicationFiled: August 19, 2014Publication date: February 26, 2015Inventors: Marcus Knell, Guido Endert, Horst Wergen
-
Publication number: 20130274270Abstract: Polymorphs of 3-chloro-4[(2R)-2-(4-chlorophenyl)-4-[(1R)-1-(4-cyanophenyl)ethyl]-1-piperazinyl]-benzonitrile are disclosed, as well as pharmaceutical compositions comprising said polymorphs, methods of using the polymorphs, and a process for preparing them.Type: ApplicationFiled: December 21, 2011Publication date: October 17, 2013Inventors: Monika Brink, Hans-Peter Niedermann, Marcus Knell, Tao Feng, Scott T. Trzaska, Arthur J. Cooper, Shaileshkumar Ramanial Desai, Vinayak Keshav Gore
-
Patent number: 7692020Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R1 have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110° C. to 160° C.; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR1, wherein X and R1 have the meaning given, optionally in the presence of a solvent and/or a base.Type: GrantFiled: October 26, 2006Date of Patent: April 6, 2010Assignee: BASF SEInventors: Monika Brink, Marcus Knell, Jan Hendrik Wevers
-
Publication number: 20080249313Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R1 have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110° C. to 160° C.; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR1, wherein X and R1 have the meaning given, optionally in the presence of a solvent and/or a base.Type: ApplicationFiled: October 26, 2006Publication date: October 9, 2008Applicant: BASF SEInventors: Monika Brink, Marcus Knell, Jan Hendrik Wevers