Patents by Inventor Marcus Knell

Marcus Knell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964102
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: April 23, 2024
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Patent number: 11679212
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: June 20, 2023
    Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBH
    Inventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Publication number: 20210107874
    Abstract: The present invention is directed to a salt of a compound of formula (I), R1 is halogen or methyl; X is methyl, OR2, or SR2; Y1, Y2 is CR3 or N, and one of Y1, Y2 is N and one of Y1, Y2 is CR3; R2 is methyl or ethyl; R3 is hydrogen or methyl, wherein the salt is chosen from the group 10 consisting of malate salt, citrate salt, tartrate salt, oxalate salt, fumarate salt, lactate salt, glucoronate salt, oxoglucoronate salt, ethanesulfonate salt, and succinate salt. The present invention is further related to a pharmaceutical formulation comprising the salt of the invention wherein the base compound is present in an amount of 2-30% (w/v) and having a pH value of at least 3.7 and to methods of treatment using the salt of the invention.
    Type: Application
    Filed: March 30, 2018
    Publication date: April 15, 2021
    Applicant: Intervet Inc.
    Inventors: Michael Berger, Hans Peter Niedermann, Marcus Knell, Anne Lehay, Angelique Duval, Anne-Laure Morer, Susi Alteheld
  • Publication number: 20210038837
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.
    Type: Application
    Filed: October 29, 2020
    Publication date: February 11, 2021
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Patent number: 10869975
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: December 22, 2020
    Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBH
    Inventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Publication number: 20200353188
    Abstract: An inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 12, 2020
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Guido Endert, Horst Wergen
  • Publication number: 20200283389
    Abstract: An improved process for producing a compound of Formula (I).
    Type: Application
    Filed: December 22, 2016
    Publication date: September 10, 2020
    Applicant: Intervet Inc.
    Inventors: Michael Berger, Hans Peter Niedermann, Tobias Kappesser, Stephan Veit, Heiko Bothe, Marcus Knell, Christophe Pierre Alain Chassaing
  • Patent number: 10737046
    Abstract: An inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: August 11, 2020
    Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBH
    Inventors: Marcus Knell, Guido Endert, Horst Wergen
  • Publication number: 20180361088
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 20, 2018
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Patent number: 10046124
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: August 14, 2018
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Publication number: 20180161528
    Abstract: An inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.
    Type: Application
    Filed: February 6, 2018
    Publication date: June 14, 2018
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Guido Endert, Horst Wergen
  • Patent number: 9913952
    Abstract: This invention relates to an inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: March 13, 2018
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Guido Endert, Horst Wergen
  • Publication number: 20170281886
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.
    Type: Application
    Filed: June 19, 2017
    Publication date: October 5, 2017
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Patent number: 9713516
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: July 25, 2017
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Publication number: 20150053202
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 26, 2015
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Michael Aven, Benjamin Franzmann, Steffen Schuy, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Publication number: 20150053203
    Abstract: This invention relates to an inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 26, 2015
    Inventors: Marcus Knell, Guido Endert, Horst Wergen
  • Publication number: 20150053207
    Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 26, 2015
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Marcus Knell, Herbert Wachtel, Guido Endert, Alexander Christ, Horst Wergen
  • Publication number: 20130274270
    Abstract: Polymorphs of 3-chloro-4[(2R)-2-(4-chlorophenyl)-4-[(1R)-1-(4-cyanophenyl)ethyl]-1-piperazinyl]-benzonitrile are disclosed, as well as pharmaceutical compositions comprising said polymorphs, methods of using the polymorphs, and a process for preparing them.
    Type: Application
    Filed: December 21, 2011
    Publication date: October 17, 2013
    Inventors: Monika Brink, Hans-Peter Niedermann, Marcus Knell, Tao Feng, Scott T. Trzaska, Arthur J. Cooper, Shaileshkumar Ramanial Desai, Vinayak Keshav Gore
  • Patent number: 7692020
    Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R1 have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110° C. to 160° C.; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR1, wherein X and R1 have the meaning given, optionally in the presence of a solvent and/or a base.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: April 6, 2010
    Assignee: BASF SE
    Inventors: Monika Brink, Marcus Knell, Jan Hendrik Wevers
  • Publication number: 20080249313
    Abstract: The invention relates to a process for the preparation of pyridylcarboxylic amides and esters I, Formula (I) wherein Hal, X and R1 have the meanings given in claim 1, which comprises the following steps: (a) heating a mixture consisting essentially of trichloromethylpyridine II, Formula (II), wherein Hal has the meaning given, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, characterized in that the trichloromethylpyridine II in a liquid form is added to the concentrated sulfuric acid at a temperature from 110° C. to 160° C.; and (b) reacting the intermediate product obtained in step (a) with an amine or alcohol III, HXR1, wherein X and R1 have the meaning given, optionally in the presence of a solvent and/or a base.
    Type: Application
    Filed: October 26, 2006
    Publication date: October 9, 2008
    Applicant: BASF SE
    Inventors: Monika Brink, Marcus Knell, Jan Hendrik Wevers