Patents by Inventor Marcus Krüger

Marcus Krüger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOFORMS OF GATA6 AND NKX2-1 AS MARKERS FOR DIAGNOSIS AND THERAPY OF CANCER AND AS TARGETS FOR ANTI-CANCER THERAPY
    Publication number: 20220195529
    Abstract: The present invention relates to a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer, comprising the measurement of the amounts of specific isoforms of GATA6 and/or NKX2-1 in a sample of said subject. Furthermore, the present invention relates to a composition for use in medicine comprising (an) inhibitor(s) of specific isoforms of GATA6 and/or NKX2-1. Additionally, the present invention relates to a kit for use in a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer.
    Type: Application
    Filed: July 27, 2021
    Publication date: June 23, 2022
    Inventors: Guillermo BARRETO, Aditi MEHTA, Indrabahadur SINGH, Marten SZIBOR, Rajkumar SAVAI, Werner SEEGER, Thomas BRAUN, Andreas GÜNTHER, Marcus KRÜGER
  • ISOFORMS OF GATA6 AND NKX2-1 AS MARKERS FOR DIAGNOSIS AND THERAPY OF CANCER AND AS TARGETS FOR ANTI-CANCER THERAPY
    Publication number: 20200181717
    Abstract: The present invention relates to a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer, comprising the measurement of the amounts of specific isoforms of GATA6 and/or NKX2-1 in a sample of said subject. Furthermore, the present invention relates to a composition for use in medicine comprising (an) inhibitor(s) of specific isoforms of GATA6 and/or NKX2-1. Additionally, the present invention relates to a kit for use in a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer.
    Type: Application
    Filed: October 23, 2019
    Publication date: June 11, 2020
    Inventors: Guillermo BARRETO, Aditi MEHTA, Indrabahadur SINGH, Marten SZIBOR, Rajkumar SAVAI, Werner SEEGER, Thomas BRAUN, Andreas GÜNTHER, Marcus KRÜGER
  • Isoforms of GATA6 and NKX2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy
    Patent number: 10501803
    Abstract: The present invention relates to a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer, comprising the measurement of the amounts of specific isoforms of GATA6 and/or NKX2-1 in a sample of said subject. Furthermore, the present invention relates to a composition for use in medicine comprising (an) inhibitor(s) of specific isoforms of GATA6 and/or NKX2-1. Additionally, the present invention relates to a kit for use in a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: December 10, 2019
    Assignees: MAX-PLANCK GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V., JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN
    Inventors: Guillermo Barreto, Aditi Mehta, Indrabahadur Singh, Marten Szibor, Rajkumar Savai, Werner Seeger, Thomas Braun, Andreas Günther, Marcus Krüger
  • ISOFORMS OF GATA6 AND NKX2-1 AS MARKERS FOR DIAGNOSIS AND THERAPY OF CANCER AND AS TARGETS FOR ANTI-CANCER THERAPY
    Publication number: 20160244842
    Abstract: The present invention relates to a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer, comprising the measurement of the amounts of specific isoforms of GATA6 and/or NKX2-1 in a sample of said subject. Furthermore, the present invention relates to a composition for use in medicine comprising (an) inhibitor(s) of specific isoforms of GATA6 and/or NKX2-1. Additionally, the present invention relates to a kit for use in a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer.
    Type: Application
    Filed: May 21, 2014
    Publication date: August 25, 2016
    Inventors: Guillermo BARRETO, Aditi MEHTA, Indrabahadur SINGH, Marten SZIBOR, Rajkumar SAVAI, Werner SEEGER, Thomas BRAUN, Andreas GÜNTHER, Marcus KRÜGER
  • ISOTOPIC LABELING OF HIGHER ORGANISMS
    Publication number: 20140328760
    Abstract: The invention generally relates to metabolic labeling of a target organism with a stable isotope. In a first aspect, the present invention relates to a method for metabolic labeling of a target organism with a stable isotope. The present invention also relates to a method of producing a diet for metabolic labeling of a target organism and to a diet composition for metabolic labeling of a target organism. In a further aspect the invention describes the use of the diet composition according to the present invention for producing a metabolically labeled target organism as a reference for a quantitative proteomic approach. The present invention also relates, in a further aspect, to the use of a diet composition for pulse SILAC labeling. The present invention also relates to the use of a target organism labeled by the method according to the first aspect of the present invention as a spike-in standard in quantitative proteomics approaches.
    Type: Application
    Filed: November 28, 2012
    Publication date: November 6, 2014
    Applicant: SILANTES GMBH
    Inventors: Marcus Krüger, Hermann Heumann
  • HAIR CONDITIONERS COMPRISING SELECTED CATIONIC SILICONES AND DIMETHICONE
    Publication number: 20120121529
    Abstract: Hair preparations containing selected cationic silicones and dimethicone are used for the treatment of keratin fibers, in particular human hair.
    Type: Application
    Filed: January 20, 2012
    Publication date: May 17, 2012
    Applicant: Henkel AG & Co. KGaA
    Inventor: Marcus Krüger
  • HAIR CONDITIONERS COMPRISING SELECTED CATIONIC SILICONES AND A B SERIES VITAMIN
    Publication number: 20120114586
    Abstract: The invention relates to hair preparations containing selected cationic silicones and at least one B series vitamin as well as to the use of said preparations for the treatment of keratin fibers, in particular human hair.
    Type: Application
    Filed: January 20, 2012
    Publication date: May 10, 2012
    Applicant: Henkel AG & Co. KGaA
    Inventor: Marcus Krüger