Patents by Inventor Marcus Michael Seldin

Marcus Michael Seldin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Myonectin (CTRP15), compositions comprising same, and methods of use
    Patent number: 9545433
    Abstract: Disclosed is the novel myokine known as myonectin (CTRP15), an isolated nucleic acid encoding the myonectin (CTRP15) gene, and the amino acid sequence encoding the myonectin (CTRP15) protein. Methods of isolation of the nucleic acid, protein, polypeptides and methods of making anybodies to myonectin (CTRP15) protein are provided. The use of myonectin (CTRP15) in the modulation of lipid and/or glucose metabolism, suppressing the expression of autophagy genes, inhibiting LC3 lipidation and autophagosome-dependent p62 degradation, and activating the Akt/mTOR pathway is also provided.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: January 17, 2017
    Assignee: The Johns Hopkins University
    Inventors: Guang William Wong, Marcus Michael Seldin
  • MYONECTIN (CTRP15), COMPOSITIONS COMPRISING SAME, AND METHODS OF USE
    Publication number: 20160143994
    Abstract: Disclosed is the novel myokine known as myonectin (CTRP15) an isolated nucleic acid encoding the myonectin (CTRP15) gene, and the amino acid sequence encoding the myonectin (CTRP15) protein. Methods of isolation of the nucleic acid, protein, polypeptides and methods of making anybodies to myonectin (CTRP15) protein are provided. The use of myonectin (CTRP15) in the modulation of lipid and/or glucose metabolism, suppressing the expression of autophagy genes, inhibiting LC3 lipidation and autophagosome-dependent p62 degradation, and activating the Akt/mTOR pathway is also provided.
    Type: Application
    Filed: November 25, 2015
    Publication date: May 26, 2016
    Inventors: Guang William Wong, Marcus Michael Seldin
  • Myonectin (CTRP15), compositions comprising same, and methods of use
    Patent number: 9228005
    Abstract: Disclosed is the novel myokine known as myonectin (CTRP15), an isolated nucleic acid encoding the myonectin (CTRP15) gene, and the amino acid sequence encoding the myonectin (CTRP15) protein. Methods of isolation of the nucleic acid, protein, polypeptides and methods of making antibodies to the myonectin (CTRP15) protein are provided. The use of myonectin (CTRP15) in the modulation of lipid and/or glucose metabolism, suppressing the expression of autophagy genes, inhibiting LC3 lipidation and autophagosome-dependent p62 degradation, and activating the Akt/mTOR pathway is also provided.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: January 5, 2016
    Assignee: The Johns Hopkins University
    Inventors: Guang William Wong, Marcus Michael Seldin
  • MYONECTIN (CTRP15), COMPOSITIONS COMPRISING SAME, AND METHODS OF USE
    Publication number: 20140371142
    Abstract: Disclosed is the novel myokine known as myonectin (CTRP15), an isolated nucleic acid encoding the myonectin (CTRP15) gene, and the amino acid sequence encoding the myonectin (CTRP15) protein. Methods of isolation of the nucleic acid, protein, polypeptides and methods of making antibodies to the myonectin (CTRP15) protein are provided. The use of myonectin (CTRP15) in the modulation of lipid and/or glucose metabolism, suppressing the expression of autophagy genes, inhibiting LC3 lipidation and autophagosome-dependent p62 degradation, and activating the Akt/mTOR pathway is also provided.
    Type: Application
    Filed: January 24, 2013
    Publication date: December 18, 2014
    Inventors: Guang William Wong, Marcus Michael Seldin