Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: A method for producing a connection between component parts and a component made of component parts are disclosed. In an embodiment, a includes providing a first component part having a first exposed insulation layer and a second component part having a second exposed insulation layer, wherein each of the insulation layers has at least one opening, joining together the first and second component parts such that the opening of the first insulation layer and the opening of the second insulation layer overlap in top view, wherein an Au layer and a Sn layer are arranged one above the other in at least one of the openings and melting the Au layer and the Sn layer to form an AuSn alloy, wherein the AuSn alloy forms a through-via after cooling electrically conductively connecting the first component part to the second component part.

Abstract: A disc brake for utility vehicles includes a brake disc, a first brake lining on a first side of the brake disc and a second brake lining on a second side of the brake disc opposite the first side. A spreading device is also provided which generates a force that moves the first and the second brake lining away from one another.

Abstract: Layer constructions allow an adhesive tape to be wound to form a spool simply and with relatively uncomplicated apparatus. At least one layered construction comprises: an adhesive tape comprising at least one outer layer of pressure-sensitive adhesive; a release liner lying on the outer layer of pressure-sensitive adhesive; and an interliner lying on the side of the adhesive tape opposite the outer layer of pressure-sensitive adhesive, at least the side of the interliner facing away from the adhesive tape being adhesively furnished, wherein all layers of the layered construction finish substantially flush with respect to each other. At least one spool comprising a spool core and the at least one layered construction wound crosswise in a plurality of plies on said core, and a method for producing the at least one spool are also disclosed.

Abstract: A swing device for moving a blood bag includes a stand, a tray for receiving the blood bag, the tray being pivotable with respect to the stand, an electromotive drive device operatively coupled to the tray for causing a rocking movement of the tray with respect to the stand, and a control device for controlling operation of the drive device. The drive device includes a rotatable shaft member which is rotatable for driving the rocking movement of the tray. The drive device also includes a position encoding device configured to encode a rotary position of the rotatable shaft member of the drive device, wherein the control device is configured to determine a position of the tray with respect to the stand based on an encoder value indicative of the rotary position of the rotatable shaft member.

Abstract: A clamping device for acting onto a medical tubing includes a clamp arrangeable on the medical tubing and displaceable between an open position in which the clamp unblocks the medical tubing and a close position in which the clamp closes the medical tubing. The clamping device further includes a drive system configured to act on the clamp for switching the clamp between the open position and the close position. The clamping device also includes a main control circuit and a secondary control circuit electronically independent from the main control circuit, and a relay switchable between a first position and a second position. In the first position, the relay electronically couples the drive system to the main control circuit while the drive system is electronically decoupled from the secondary control circuit. In the second position, the relay electronically couples the drive system to the secondary control circuit while the drive system is electronically decoupled from the main control circuit.

Abstract: A welding apparatus (1) for radio-frequency, RF, welding, comprises: a clamp (10) having two electrodes (100, 101; 100?, 101?) being movable with respect to one another for clamping one or more items (2; 2?) therebetween for a welding process; and an RF power supply (11) for providing an RF welding current to the electrodes (100, 101; 100?, 101?) of the clamp (10), the RF power supply being adapted to change the frequency of the RF welding current during the welding process.

Abstract: An embedded information system includes a load control circuit coupleable to an external memory that contains instructions and constant data (organized by variable sized load units, LUs, and where at least one property of a LU is specified within metadata) associated with application code of a software application, at least one processor configured to execute the at least one application code; an internal memory configured as main system memory in a first part and as a cache for storing the instructions and constant data for an execution of the at least one application code from the external memory in a second part. The load control circuit is configured to load the LUs associated with the at least one application code from the external memory with a granularity of a single LU into the internal memory.

Abstract: A method of managing load units of executable instructions between internal memory in a microcontroller with multiple bus masters, and a non-volatile memory device external to the microcontroller. A copy of the load units are loaded from the external memory device into the internal memory for use by corresponding bus masters. Each load unit is with a corresponding load entity queue and each load entity queue is associated with a corresponding one of the multiple bus masters. Each load entity queue selects an eviction candidate from the associated copy of the load units currently loaded in the internal memory. Information identifying the eviction candidate for each load entity queue is broadcasted to all load entity queues. The eviction candidate is added to a set of managed eviction candidates if none of the load entity queues vetoes using the eviction candidate.

Abstract: A processor scheduling structure, a method and an integrated circuit are provided. In accordance with at least one embodiment, the processor scheduling structure comprises a processor circuit and an operating system task aware caching (OTC) controller circuit coupled to the processor circuit. The OTC controller circuit comprises a load request timer, a load sequence queue (LSQ), and a request arbiter. The timer and the LSQ are coupled to and provide inputs to the request arbiter. The processor circuit comprises an internal memory and a processor core. The OTC controller circuit is configured to schedule processor tasks for the processor circuit in accordance with both priority-based scheduling, using the LSQ, and time-triggered scheduling, using the load request timer.

Abstract: The present invention provides a robust single clone Master Cell Bank (MCB) for an optimized production of H-1 parvovirus (H-1 PV) which is suitable to increase infectious parvovirus production compared to standard producer NB-324K mixed cells.

Abstract: A circuit includes a one-time programmable (OTP) storage element configured to store a first logic value, an access delay timer configured to initiate a timer in response to a reset event with a timer value, and an access control circuit coupled to the access delay timer and the OTP storage element. The access control circuit is configured to count a number of access requests to the OTP storage element granted by the access control circuit and to store the number of granted access requests to the OTP storage element as a count value. The access control circuit is also configured to grant access to the OTP storage element in response to an access request only when the timer has expired and the count value is less than a predetermined count threshold.

Abstract: A method of managing load units of executable instructions between internal memory in a microcontroller with multiple bus masters, and a non-volatile memory device external to the microcontroller. A copy of the load units are loaded from the external memory device into the internal memory for use by corresponding bus masters. Each load unit is with a corresponding load entity queue and each load entity queue is associated with a corresponding one of the multiple bus masters. Each load entity queue selects an eviction candidate from the associated copy of the load units currently loaded in the internal memory. Information identifying the eviction candidate for each load entity queue is broadcasted to all load entity queues. The eviction candidate is added to a set of managed eviction candidates if none of the load entity queues vetoes using the eviction candidate.

Abstract: An embedded information system includes a load control circuit coupleable to an external memory that contains instructions and constant data (organized by variable sized load units, LUs, and where at least one property of a LU is specified within metadata) associated with application code of a software application, at least one processor configured to execute the at least one application code; an internal memory configured as main system memory in a first part and as a cache for storing the instructions and constant data for an execution of the at least one application code from the external memory in a second part. The load control circuit is configured to load the LUs associated with the at least one application code from the external memory with a granularity of a single LU into the internal memory.

Abstract: A method for improved distribution of a software client application includes: in a first step, an initializing software application is transmitted to a client computing device, wherein the initializing software application is related to the software client application and corresponds to a preliminary part of the software client application; and in a second step subsequent to the first step and upon being requested by the initializing software application, software code of the software client application is transmitted to the client computing device in view of the software client application being installed and/or activated on the client computing device in order to provide the cloud-based communication service.

Abstract: A processor scheduling structure, a method and an integrated circuit are provided. In accordance with at least one embodiment, the processor scheduling structure comprises a processor circuit and an operating system task aware caching (OTC) controller circuit coupled to the processor circuit. The OTC controller circuit comprises a load request timer, a load sequence queue (LSQ), and a request arbiter. The timer and the LSQ are coupled to and provide inputs to the request arbiter. The processor circuit comprises an internal memory and a processor core. The OTC controller circuit is configured to schedule processor tasks for the processor circuit in accordance with both priority-based scheduling, using the LSQ, and time-triggered scheduling, using the load request timer.

Abstract: A processor scheduling structure, a method and an integrated circuit are provided. In accordance with at least one embodiment, the processor scheduling structure comprises a processor circuit and an operating system task aware caching (OTC) controller circuit coupled to the processor circuit. The OTC controller circuit comprises a load request timer, a load sequence queue (LSQ), and a request arbiter. The timer and the LSQ are coupled to and provide inputs to the request arbiter. The processor circuit comprises an internal memory and a processor core. The OTC controller circuit is configured to schedule processor tasks for the processor circuit in accordance with both priority-based scheduling, using the LSQ, and time-triggered scheduling, using the load request timer.

Abstract: Described is a reproducible, effective and scalable process for parvovirus production including characterization strategies, preferably production of H-1PV.

Abstract: The present disclosure discloses an image registration method and apparatus. The method includes: determining a target plane; orthogonally projecting the optical center of each of the cameras in the planar camera array onto the target plane, to obtain a projected point of the optical center of each of the cameras; generating a rectangular grid on the target plane according to the projected points of the optical centers of the cameras in the planar camera array; obtaining a target grid point of each of the cameras according to the rectangular grid; determining a target camera coordinate system of each of the cameras; and registering, images collected by the cameras in the planar camera array. In embodiments of the present disclosure a target camera coordinate system of a camera is determined again, thereby greatly reducing complexity of subsequent image registration.

Abstract: Described is a reproducible, effective and scalable process for parvovirus production including characterization strategies, preferably production of H-1PV.