Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: A data collection device comprises: a first portion having one or more features configured for attaching of the first portion to a dosage knob of an injection device; a second portion rotatably coupled with the first portion, wherein at least part of the second portion is movable axially relative to the first portion; a sensor arrangement configured to detect rotation of the first portion relative to the second portion; and a processor arrangement configured to, based on said detected movement, determine a medicament amount expelled by the injection device, wherein the coupling arrangement is configured to provide a non-permanent coupling between the first portion and the dosage knob of the injection device.

Abstract: A data collection device comprises: a first portion having one or more features configured for attaching of the first portion to a dosage knob of an injection device; a second portion rotatably coupled with the first portion, wherein at least part of the second portion is movable axially relative to the first portion; a sensor arrangement configured to detect rotation of the first portion relative to the second portion; and a processor arrangement configured to, based on said detected movement, determine a medicament amount expelled by the injection device, wherein the coupling arrangement is configured to provide a non-permanent coupling between the first portion and the dosage knob of the injection device.

Abstract: A disc brake for utility vehicles includes a brake disc, a first brake lining on a first side of the brake disc and a second brake lining on a second side of the brake disc opposite the first side. A spreading device is also provided which generates a force that moves the first and the second brake lining away from one another.

Abstract: Layer constructions allow an adhesive tape to be wound to form a spool simply and with relatively uncomplicated apparatus. At least one layered construction comprises: an adhesive tape comprising at least one outer layer of pressure-sensitive adhesive; a release liner lying on the outer layer of pressure-sensitive adhesive; and an interliner lying on the side of the adhesive tape opposite the outer layer of pressure-sensitive adhesive, at least the side of the interliner facing away from the adhesive tape being adhesively furnished, wherein all layers of the layered construction finish substantially flush with respect to each other. At least one spool comprising a spool core and the at least one layered construction wound crosswise in a plurality of plies on said core, and a method for producing the at least one spool are also disclosed.

Abstract: A swing device for moving a blood bag includes a stand, a tray for receiving the blood bag, the tray being pivotable with respect to the stand, an electromotive drive device operatively coupled to the tray for causing a rocking movement of the tray with respect to the stand, and a control device for controlling operation of the drive device. The drive device includes a rotatable shaft member which is rotatable for driving the rocking movement of the tray. The drive device also includes a position encoding device configured to encode a rotary position of the rotatable shaft member of the drive device, wherein the control device is configured to determine a position of the tray with respect to the stand based on an encoder value indicative of the rotary position of the rotatable shaft member.

Abstract: A clamping device for acting onto a medical tubing includes a clamp arrangeable on the medical tubing and displaceable between an open position in which the clamp unblocks the medical tubing and a close position in which the clamp closes the medical tubing. The clamping device further includes a drive system configured to act on the clamp for switching the clamp between the open position and the close position. The clamping device also includes a main control circuit and a secondary control circuit electronically independent from the main control circuit, and a relay switchable between a first position and a second position. In the first position, the relay electronically couples the drive system to the main control circuit while the drive system is electronically decoupled from the secondary control circuit. In the second position, the relay electronically couples the drive system to the secondary control circuit while the drive system is electronically decoupled from the main control circuit.

Abstract: A welding apparatus (1) for radio-frequency, RF, welding, comprises: a clamp (10) having two electrodes (100, 101; 100?, 101?) being movable with respect to one another for clamping one or more items (2; 2?) therebetween for a welding process; and an RF power supply (11) for providing an RF welding current to the electrodes (100, 101; 100?, 101?) of the clamp (10), the RF power supply being adapted to change the frequency of the RF welding current during the welding process.

Abstract: The present invention provides a robust single clone Master Cell Bank (MCB) for an optimized production of H-1 parvovirus (H-1 PV) which is suitable to increase infectious parvovirus production compared to standard producer NB-324K mixed cells.

Abstract: The invention relates to a block co-polymer film having different morphologies within said film, uses thereof and processes for its preparation.

Abstract: Described is a reproducible, effective and scalable process for parvovirus production including characterization strategies, preferably production of H-1PV.

Abstract: The present disclosure discloses an image registration method and apparatus. The method includes: determining a target plane; orthogonally projecting the optical center of each of the cameras in the planar camera array onto the target plane, to obtain a projected point of the optical center of each of the cameras; generating a rectangular grid on the target plane according to the projected points of the optical centers of the cameras in the planar camera array; obtaining a target grid point of each of the cameras according to the rectangular grid; determining a target camera coordinate system of each of the cameras; and registering, images collected by the cameras in the planar camera array. In embodiments of the present disclosure a target camera coordinate system of a camera is determined again, thereby greatly reducing complexity of subsequent image registration.

Abstract: Described is a reproducible, effective and scalable process for parvovirus production including characterization strategies, preferably production of H-1PV.

Abstract: Methods of fabricating complex three-dimensional structures on patterned substrates and related compositions are provided. The methods involve depositing on the substrate a block copolymer material that is “mismatched” to the substrate pattern, and then ordering the material to form a complex three-dimensional structure. According to various embodiments, the copolymer material mismatches the substrate pattern in that the symmetry and/or length scale of its bulk morphology differs from that of the pattern. When ordered, a balance between the physics that determines the bulk block copolymer morphology and the physics that determines the substrate surface interfacial interactions results in a thermodynamically stable complex three-dimensional film that varies in a direction perpendicular to the substrate and has a morphology that differs from its bulk morphology.

Abstract: The present disclosure discloses an image registration method and apparatus. The method includes: determining a target plane; orthogonally projecting the optical center of each of the cameras in the planar camera array onto the target plane, to obtain a projected point of the optical center of each of the cameras; generating a rectangular grid on the target plane according to the projected points of the optical centers of the cameras in the planar camera array; obtaining a target grid point of each of the cameras according to the rectangular grid; determining a target camera coordinate system of each of the cameras; and registering, images collected by the cameras in the planar camera array. In embodiments of the present disclosure a target camera coordinate system of a camera is determined again, thereby greatly reducing complexity of subsequent image registration.

Abstract: The present invention provides block copolymers comprising at least one covalent polymer block and at least one supramolecular polymer block, processes for their preparations and uses thereof.

Abstract: A system and method for data deduplication is presented. Data received from one or more computing systems is deduplicated, and the results of the deduplication process stored in a reference table. A representative subset of the reference table is shared among a plurality of systems that utilize the data deduplication repository. This representative subset of the reference table can be used by the computing systems to deduplicate data locally before it is sent to the repository for storage. Likewise, it can be used to allow deduplicated data to be returned from the repository to the computing systems. In some cases, the representative subset can be a proper subset wherein a portion of the referenced table is identified shared among the computing systems to reduce bandwidth requirements for reference-table synchronization.

Abstract: Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic methods, e.g., for the detection/therapy of an H-1 parvovirus infection during pregnancy since parvovirus affects about 1 in 400 pregnancies and may cause fetal loss or fetal hydrops.

Abstract: Methods of fabricating complex three-dimensional structures on patterned substrates and related compositions are provided. The methods involve depositing on the substrate a block copolymer material that is “mismatched” to the substrate pattern, and then ordering the material to form a complex three-dimensional structure. According to various embodiments, the copolymer material mismatches the substrate pattern in that the symmetry and/or length scale of its bulk morphology differs from that of the pattern. When ordered, a balance between the physics that determines the bulk block copolymer morphology and the physics that determines the substrate surface interfacial interactions results in a thermodynamically stable complex three-dimensional film that varies in a direction perpendicular to the substrate and has a morphology that differs from its bulk morphology.

Abstract: System and methods for selectively or automatically migrating resources between storage operation cells are provided. In accordance with one aspect of the invention, a management component within the storage operation system may monitor system operation and migrate components from storage operation cell to another to facilitate failover recovery, promote load balancing within the system and improve overall system performance as further described herein. Another aspect of the invention may involve performing certain predictive analyses on system operation to reveal trends and tendencies within the system. Such information may be used as the basis for potentially migrating components from one storage operation cell to another to improve system performance and reduce or eliminate resource exhaustion or congestion conditions.