Patents by Inventor Marcus Persicke

Marcus Persicke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the improved formation of acarbose
    Patent number: 12351847
    Abstract: The present invention relates to Actinomycetales strains for the improved formation of acarbose. Provided are Actinomycetales strains which are engineered to overexpress dTDP-D-glucose-4,6-dehydratase (AcbB) and/or uridyltransferase (GtaB). Also provided are Actinomycetales strains which are engineered to have a reduced or absent expression of the small carbohydrate binding protein (Cgt) and/or a reduced or absent expression of genes which are essential for carotenoid synthesis. Also provided are tools, methods and means to generate these strains.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: July 8, 2025
    Inventors: Alfred Puhler, Jorn Kalinowski, Susanne Schneiker-Bekel, Marcus Persicke, Lena Schaffert
  • METHODS FOR THE IMPROVED FORMATION OF ACARBOSE
    Publication number: 20230227879
    Abstract: The present invention relates to Actinomycetales strains for the improved formation of acarbose. Provided are Actinomycetales strains which are engineered to overexpress dTDP-D-glucose-4,6-dehydratase (AcbB) and/or uridyltransferase (GtaB). Also provided are Actinomycetales strains which are engineered to have a reduced or absent expression of the small carbohydrate binding protein (Cgt) and/or a reduced or absent expression of genes which are essential for carotenoid synthesis. Also provided are tools, methods and means to generate these strains.
    Type: Application
    Filed: October 2, 2020
    Publication date: July 20, 2023
    Inventors: Alfred Puhler, Jorn KALINOWSKI, Susanne SCHNEIKER-BEKEL, Marcus PERSICKE, Lena SCHAFFERT
  • Method for Producing L-Amino Acids Using an Alkaliphilic Bacteria
    Publication number: 20170051323
    Abstract: Surprisingly, it has been found that alkaliphilic bacteria of the genus Corynebacterium are naturally suited to produce L-amino acids.
    Type: Application
    Filed: April 16, 2015
    Publication date: February 23, 2017
    Applicant: Evonik Degussa GmbH
    Inventors: Ines OCHROMBEL, Brigitte BATHE, Marleen HASSELMEYER, Jörn Kalinowski, Christian Rückert, Marcus Persicke
  • MICROORGANISM AND METHOD FOR PRODUCTION OF AMINO ACIDS BY FERMENTATION
    Publication number: 20160265072
    Abstract: The invention relates to a microorganism that produces and/or secretes an organic chemical compound, wherein the microorganism has an increased expression, compared to the respective starting strain, of a polypeptide LpdA with the activity of a transhydrogenase; and a process for producing an organic chemical compound using the microorganism according to the invention.
    Type: Application
    Filed: January 13, 2014
    Publication date: September 15, 2016
    Inventors: Frederik Walter, Marcus Persicke, Jorn Kalinowski, Andrea Huser, Wilfried Claes, Alexander Reth
  • MICROORGANISM AND METHOD FOR PRODUCTION OF AMINO ACIDS BY FERMENTATION
    Publication number: 20160053335
    Abstract: The invention relates to a microorganism that produces and/or secretes an organic chemical compound, wherein the microorganism has an increased expression, compared to the respective starting strain, of a polypeptide LpdA with the activity of a transhydrogenase; and a process for producing an organic chemical compound using the microorganism according to the invention.
    Type: Application
    Filed: January 13, 2014
    Publication date: February 25, 2016
    Inventors: Frederik Walter, Marcus Persicke, Jörn Kalinowski, Andrea Hüser, Wilfried Claes, Alexander Reth