Abstract: In one aspect, the disclosure relates to substituted N-(2-(2,6-dioxopiperidinyl-3-yl)-1,3-dioxoisoindolin-5-yl)arylsulfonamide analogs that useful as modulators of cereblon (CRBN) activity, methods of making same, pharmaceutical compositions comprising same, and methods of treating various clinical conditions and disorders using same, e.g., a disorder of uncontrolled cellular proliferation, such as a cancer, which may be associated with cereblon protein dysfunction and/or a GSPT1 dysfunction. In various further aspects, the disclosed compounds can selectively modulate the degradation of GSPT1 protein, i.e., the disclosed compounds can act as GSPT1 degraders. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: A charging station for charging a battery of an electric vehicle including: a main body having a base portion positioned in a substructure and a charging portion, the charging portion includes an electrical outlet for connection to the electric vehicle; lifting means for moving the charging portion between a first position in which the charging portion is located in the base portion and a second position in which the charging portion is in a raised location out of the base portion and above the substructure; a lifting controller to activate the lifting means to move the charging portion between the first position and second position. The charging station is operable to charge the vehicle when the charging portion is in the first position within the base portion.

Abstract: A charging station for charging a battery of an electric vehicle including: a main body having a base portion positioned in a substructure and a charging portion, the charging portion includes an electrical outlet for connection to the electric vehicle; lifting means for moving the charging portion between a first position in which the charging portion is located in the base portion and a second position in which the charging portion is in a raised location out of the base portion and above the substructure; a lifting controller to activate the lifting means to move the charging portion between the first position and second position. The charging station is operable to charge the vehicle when the charging portion is in the first position within the base portion.