Patents by Inventor Marcus Semones

Marcus Semones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20080287466
    Abstract: Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Application
    Filed: July 9, 2008
    Publication date: November 20, 2008
    Inventors: Jerry Leroy Adams, Deborah Lynne Bryan, Yanhong Feng, Shinichiro Matsunaga, Yutaka Maeda, Yasushi Miyazaki, Masato Nakano, Jean-Philippe Rocher, Hideyuki Sato, Marcus Semones, Domingos J. Silva, Jun Tang
  • 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof
    Patent number: 7427623
    Abstract: Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: September 23, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Deborah Lynne Bryan, Yanhong Feng, Shinichiro Matsunaga, Yutaka Maeda, Yasushi Miyazaki, Masato Nakano, Jean-Philippe Rocher, Hideyuki Sato, Marcus Semones, Domingos J. Silva, Jun Tang
  • Diamino-pyrimidines and their use as angiogenesis inhibitors
    Patent number: 7338959
    Abstract: Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: March 4, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Stanley Dawes Chamberlain, Mui Cheung, Holly Kathleen Emerson, Neil W. Johnson, Kristen Elizabeth Nailor, Douglas McCord Sammond, Marcus Semones
  • Compounds and uses thereof
    Patent number: 7005434
    Abstract: The present invention relates to novel compounds and the treatment of mammalian diseases in which inappropriate, excessive or undesirable angiogenesis has occurred and/or where excessive Tie2 receptor activity has occurred.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: February 28, 2006
    Assignee: SB Corporation
    Inventor: Marcus A. Semones
  • Diamino-pyrimidines and their use as angiogenesis inhibitors
    Publication number: 20050234083
    Abstract: Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Application
    Filed: February 28, 2003
    Publication date: October 20, 2005
    Inventors: Stanley Chamberlain, Mui Cheung, Holly Emerson, Neil Johnson, Kristen Nailor, Douglas Sammond, Marcus Semones
  • Chemical compounds
    Publication number: 20050004142
    Abstract: Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Application
    Filed: September 10, 2002
    Publication date: January 6, 2005
    Inventors: Jerry Adams, Deborah Bryan, Yanhong Feng, Shinichiro Matsunaga, Yutaka Maeda, Yasushi Miyazaki, Masato Nakano, Jean-Philippe Rocher, Hideyuki Sato, Marcus Semones, Domingos Silva, Jun Tang
  • Novel compounds and uses thereof
    Publication number: 20040048888
    Abstract: The present invention relates to novel compounds and the treatment of mammalian diseases in which inappropriate, excessive or undesirable angiogenesis has occurred and/or where excessive Tie2 receptor activity has occurred.
    Type: Application
    Filed: July 18, 2003
    Publication date: March 11, 2004
    Inventor: Marcus A. Semones