Abstract: Medicament delivery device components that compensate for manufacturing tolerances are presented, where the medicament delivery device component can have a base portion extending in an axial direction relative to an axis, a compensation member having a first portion attached to the base portion and a second portion attached to the first portion and spaced apart from the base portion in the axial direction. The second portion can have a disc extending around the axis in the circumferential direction and a protrusion extending from the disc in the axial direction, wherein the protrusion is spaced apart from the first portion in the circumferential direction. At least part of the disc is configured to flex relative to the base portion when acted on by a force in the axial direction.

Abstract: A mouthpiece for a handheld inhaler is disclosed. A housing of the mouthpiece includes an inlet, an outlet opening, and a channel extending through the housing connecting the inlet and the outlet opening for directing an aerosol from the inlet to the outlet opening. An anterior portion of the housing (4) is configured for placement in the mouth of a patient. The anterior portion of the housing is configured to direct the outlet opening upwardly in the patient's oral cavity when in the mouth of the patient. Other embodiments include an outlet opening placed closer to the upper side of the housing than to the lower side of the housing. Further, an inhaler having a mouthpiece is disclosed.

Abstract: A metered droplet medicament delivery device for delivering metered doses of medicament includes a proximal part and a distal part having opposite distal and proximal ends; a medicament container with a movable stopper; and a dose delivery mechanism that includes a plunger rod, operably arranged to act on the stopper. The proximal and distal parts are releasably connectable to each other. The proximal part includes a medicament container holder accommodating the medicament container, and the distal part includes the dose delivery mechanism. A plunger rod positioning member is engageable with a proximal end of the plunger rod and with a proximal area of the distal part for positioning the plunger rod in a longitudinal direction in relation to the proximal area.

Abstract: A mouthpiece for a handheld inhaler is disclosed. A housing of the mouthpiece includes an inlet, an outlet opening, and a channel extending through the housing connecting the inlet and the outlet opening for directing an aerosol from the inlet to the outlet opening. An anterior portion of the housing (4) is configured for placement in the mouth of a patient. The anterior portion of the housing is configured to direct the outlet opening upwardly in the patient's oral cavity when in the mouth of the patient. Other embodiments include an outlet opening placed closer to the upper side of the housing than to the lower side of the housing.

Abstract: A mouthpiece for a handheld inhaler is disclosed. A housing of the mouthpiece includes an inlet, an outlet opening, and a channel extending through the housing connecting the inlet and the outlet opening for directing an aerosol from the inlet to the outlet opening. An anterior portion of the housing (4) is configured for placement in the mouth of a patient. The anterior portion of the housing is configured to direct the outlet opening upwardly in the patient's oral cavity when in the mouth of the patient. Other embodiments include an outlet opening placed closer to the upper side of the housing than to the lower side of the housing.

Abstract: A droplet medicament delivery device for delivering a volume of a medicament from a reservoir. The device includes a device body; a valve chamber surrounded by a chamber wall movably arranged in the device body between at least a first position and a second position; at least one passage extending through the chamber wall; a valve; a valve outlet; a droplet generating device connected to the valve outlet; and an actuator arranged in the valve chamber. The actuator, when activated, delivers medicament from the valve chamber via the valve outlet. The valve inlet is open to the valve chamber and the valve outlet is closed when the chamber wall is in the first position, and the valve inlet is closed and the valve outlet is open when the chamber wall is in the second position.

Abstract: A metered droplet medicament delivery device for delivering metered doses of medicament includes a proximal part and a distal part having opposite distal and proximal ends; a medicament container with a movable stopper; and a dose delivery mechanism that includes a plunger rod, operably arranged to act on the stopper. The proximal and distal parts are releasably connectable to each other. The proximal part includes a medicament container holder accommodating the medicament container, and the distal part includes the dose delivery mechanism. A plunger rod positioning member is engageable with a proximal end of the plunger rod and with a proximal area of the distal part for positioning the plunger rod in a longitudinal direction in relation to the proximal area.

Abstract: A medicament delivery device for delivering metered doses of medicament, wherein an indicator mechanism (128, 132) is operably connected to an drive member (118) and arranged to visibly indicate to a user of the device when a spring force tensioning member (166) has been operated such that the device is ready for dose delivery.

Abstract: The present invention relates to an isolated ?-actin nucleic acid promoter molecule from shrimp; nucleic acid constructs including the ?-actin promoter molecule; and expression vectors, host cells, and transgenic animals transduced with the isolated ?-actin nucleic acid promoter. Also disclosed are methods for imparting to an animal resistance against a pathogen, regulating growth of an animal, increasing stress tolerance in an animal, and increasing cold tolerance in an animal that involves transforming an animal with a nucleic acid construct including the isolated ?-actin nucleic acid promoter molecule of the present invention.

Abstract: The invention relates to a mobile communication device, with a casing and a keypad comprising a plurality of keys and a plurality of rotatable key elements comprising a protrusion. Each key element is adapted to depress a first key in a first direction, when rotated in a first rotating direction, and depress a second key in said first direction, when rotated in a second rotating direction. Each key element is adapted to be rotated in said first rotating direction upon application of a force onto the protrusion in a second direction. Each key element is adapted to be rotated in said second rotating direction upon application of a force onto the protrusion in a third direction. The second and third direction is opposite to each other, and the first direction is perpendicular to said second and said third direction.

Abstract: A portable electronic device (1) comprising a first portion (3, 53) including at least one output device (2) for rendering output data and a second portion (4, 54) comprising at least two input devices (10, 11, 20, 30, 40) for manually inputting data into the portable electronic device. The second portion is rotatably connected to the first portion. The output device is directed in the same direction as a first input device when the second portion is positioned in a first position, and in the same direction as another input device when the second portion is positioned in a second position.

Abstract: The invention relates to a mobile communication device, with a casing and a keypad comprising a plurality of keys and a plurality of rotatable key elements comprising a protrusion. Each key element is adapted to depress a first key in a first direction, when rotated in a first rotating direction, and depress a second key in said first direction, when rotated in a second rotating direction. Each key element is adapted to be rotated in said first rotating direction upon application of a force onto the protrusion in a second direction. Each key element is adapted to be rotated in said second rotating direction upon application of a force onto the protrusion in a third direction. The second and third direction is opposite to each other, and the first direction is perpendicular to said second and said third direction.

Abstract: A portable electronic device (1) comprising a first portion (3, 53) including at least one output device (2) for rendering output data and a second portion (4, 54) comprising at least two input devices (10, 11, 20, 30, 40) for manually inputting data into the portable electronic device. The second portion is rotatably connected to the first portion. The output device is directed in the same direction as a first input device when the second portion is positioned in a first position, and in the same direction as another input device when the second portion is positioned in a second position.

Abstract: The present invention relates to an isolated ?-actin nucleic acid promoter molecule from shrimp; nucleic acid constructs including the ?-actin promoter molecule; and expression vectors, host cells, and transgenic animals transduced with the isolated ?-actin nucleic acid promoter. Also disclosed are methods for imparting to an animal resistance against a pathogen, regulating growth of an animal, increasing stress tolerance in an animal, and increasing cold tolerance in an animal that involves transforming an animal with a nucleic acid construct including the isolated ?-actin nucleic acid promoter molecule of the present invention.

Abstract: The present invention is directed towards a portable electronic device that includes a first part and a second part. The first part includes electrical circuits and has an exterior side, an interior side, and a bottom side. The second part includes electrical circuits and has an exterior side, and interior side and a bottom side. At least one hinge connects the bottom sides of the first and second parts to each other and allows rotation of one part in relation to the other. At least one first set of flexible electrical conductors are connected to the first part on the exterior side adjacent the bottom side thereof and connected to the second part on the interior side adjacent the bottom side thereof. The first part may be a camera having a lens on the interior side thereof, and the second part may be a display provided on the interior side thereof.

Abstract: The present invention is directed towards a portable electronic device that includes a first part and a second part. The first part includes electrical circuits and has an exterior side, an interior side, and a bottom side. The second part includes electrical circuits and has an exterior side, and interior side and a bottom side. At least one hinge connects the bottom sides of the first and second parts to each other and allows rotation of one part in relation to the other. At least one first set of flexible electrical conductors are connected to the first part on the exterior side adjacent the bottom side thereof and connected to the second part on the interior side adjacent the bottom side thereof. The first part may be a camera having a lens on the interior side thereof, and the second part may be a display provided on the interior side thereof.