Patents by Inventor Marcus STOIBER

Marcus STOIBER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanopore sequencing base calling
    Patent number: 12385899
    Abstract: Disclosed herein are systems and methods for nanopore sequencing basecalling. In one embodiment, the method can include: receiving raw nanopore sequencing data comprising a plurality of continuous data acquisition (DAC) values corresponding to a biomolecule; normalizing the raw nanopore sequencing data to generate normalized nanopore sequencing data comprising a plurality of normalized DAC values; generating, using a first neural network (NN) and a normalized DAC value of the plurality of normalized DAC values, a vector of transformed probability values, segmenting the plurality of normalized DAC values into a plurality of discrete events; generating, using a second neural network and the event vector, an element determination of the biomolecule.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: August 12, 2025
    Assignee: The Regents of the University of California
    Inventors: Marcus Stoiber, James Brown
  • NANOPORE SEQUENCING BASE CALLING
    Publication number: 20190204296
    Abstract: Disclosed herein are systems and methods for nanopore sequencing basecalling. In one embodiment, the method can include: receiving raw nanopore sequencing data comprising a plurality of continuous data acquisition (DAC) values corresponding to a biomolecule; normalizing the raw nanopore sequencing data to generate normalized nanopore sequencing data comprising a plurality of normalized DAC values; generating, using a first neural network (NN) and a normalized DAC value of the plurality of normalized DAC values, a vector of transformed probability values, segmenting the plurality of normalized DAC values into a plurality of discrete events; generating, using a second neural network and the event vector, an element determination of the biomolecule.
    Type: Application
    Filed: July 10, 2017
    Publication date: July 4, 2019
    Applicant: The Regents of the University of California
    Inventors: Marcus STOIBER, James BROWN