Patents by Inventor Marcus Trunk

Marcus Trunk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for improved diagnosis of dysplasias
    Patent number: 9528159
    Abstract: The present invention relates to a method for improved diagnosis of dysplasias based on simultaneous detection of INK4a gene products and at least one marker for cell proliferation. Particularly the present invention provides a method for discriminating dysplastic cells over-expressing INK4a gene products from cells over-expressing INK4a gene products without being dysplastic by detection of a marker suitable for characterizing the proliferation properties of the respective cell. The characterization of the proliferation properties may comprise the detection of a marker or a set of markers characteristic for active cell proliferation and/or a marker or a set of markers characteristic for retarded or ceased cell proliferation. The method presented herein thus enables for a specific diagnosis of dysplasias in histological and cytological specimens.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: December 27, 2016
    Assignee: VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Ruediger Ridder, Anja Reichert, Marcus Trunk, Richard Batrla