Patents by Inventor Mareike Bongers

Mareike Bongers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC MICROBES
    Publication number: 20230263864
    Abstract: The invention relates to microbial cells and microbial cells for use as a medicament, the cells expressing a recombinant nucleic acid encoding a eukaryotic tyrosine hydroxylase. The cells produce L-DOPA and dopamine.
    Type: Application
    Filed: July 15, 2021
    Publication date: August 24, 2023
    Inventors: Mareike BONGERS, Felipe TUEROS FARFAN, Morten SOMMER, Frederik NEERGAARD, Susanne KAMMLER
  • ADVANCED MICROBIOME THERAPEUTICS ENGINEERED TO PRODUCE SEROTONIN IN VIVO
    Publication number: 20230098772
    Abstract: The invention provides a composition for use as a medicament, comprising cells of a recombinant microorganism capable of producing increased amounts of one or more of 5-hydroxytryptophan (5-HTP), 5-hydroxytryptamine (5-HT) and tryptamine (TRM) as compared to the non-recombinant microorganism from which it was derived. The composition finds use in preventing and/or treating TRM-; 5-HTP-, or 5-HT-related disorders of the central nerve system (CNS); enteric nervous system (ENS); gastro intestine (GI) and metabolism in a mammal, and may be orally administered to a mammal in need thereof. Additionally, a composition comprising cells of a recombinant microorganism capable of producing melatonin is provided for use as a medicament, such as for treatment of depression, dementia, cancer and sleep disorder.
    Type: Application
    Filed: June 12, 2020
    Publication date: March 30, 2023
    Inventors: Morten Otto Alexander Sommer, Mareike Bongers, Harris He Wang, Frank Cusimano