Abstract: A banknote processing device includes an output receptacle module, including side walls, each side wall including a flange, wherein each flange includes an aperture, a first transport plate, and a transport motor. The banknote processing device further includes a common input and discrimination module including a shaft releasably received in the aperture of each flange of the side walls of the output receptacle module, a drive shaft having one or more driven rollers coupled thereto, and a second transport plate which together with the first transport plate defines a transport path between the first and second transport plates, wherein the one or more driven rollers move banknotes along the transport path between the second and first transport plates.

Abstract: The present invention relates to nucleotides, analogs of mRNA 5?-end (cap) containing sulfur atom at the position 5? of 7-methylguanosine nucleoside. The disclosed compounds are recognized (bound and non-hydrolyzed) by DcpS enzyme (Decapping Scavenger), and thus may find therapeutic use as inhibitors thereof. DcpS is cap-specific enzyme with pyrophosphatase activity, which was identified as a therapeutic target in the treatment of spinal muscular atrophy (SMA). Some of the compounds disclosed have additional modifications in the phosphate chain, which modulate their affinity for DcpS enzyme.

Abstract: A generally vertical banknote recycling bay arrangement comprising a generally vertically oriented banknote recycling bay for receiving banknotes therein, the recycling bay having an upper end and a lower end. The arrangement further comprising a banknote feeding assembly for feeding banknotes, one at a time, into the recycling bay, the feeding assembly being positioned near the upper end of the recycling bay. The arrangement further comprising a banknote dispensing assembly for feeding banknotes, one at a time, out of the recycling bay, the dispensing assembly being positioned near the upper end of the recycling bay. The arrangement further comprising a pair of stacker wheels supported for rotational movement about a driven stacker wheel shaft, each stacker wheel being laterally moveable along the driven stacker wheel shaft and a stacker wheel positioning mechanism configured to adjust the lateral positions of the pair of stacker wheels along the stripper wheel shaft.

Abstract: The present invention relates to nucleotides, analogs of mRNA 5?-end (cap) containing sulfur atom at the position 5? of 7-methylguanosine nucleoside. The disclosed compounds are recognized (bound and non-hydrolyzed) by DcpS enzyme (Decapping Scavenger), and thus may find therapeutic use as inhibitors thereof. DcpS is cap-specific enzyme with pyrophosphatase activity, which was identified as a therapeutic target in the treatment of spinal muscular atrophy (SMA). Some of the compounds disclosed have additional modifications in the phosphate chain, which modulate their affinity for DcpS enzyme.

Abstract: A currency bill processing system includes a transport mechanism that is configured to transport bills from an input receptacle along a transport path that extends generally horizontally past at least one detector. The transport path transitions generally-vertically upward between a first and a second output receptacle. The transport mechanism is configured to deliver some of the bills toward a first end of the system into the first output receptacle and some of the bills toward a second end of the system into the second output receptacle. The system provides access openings in a front side of the system that are proximate the first and the second output receptacles thereby permitting operator access into the first and the second output receptacles from the front side.

Abstract: A currency bill processing system includes a transport mechanism that is configured to transport bills from an input receptacle along a transport path that extends generally horizontally past at least one detector. The transport path transitions generally-vertically upward between a first and a second output receptacle. The transport mechanism is configured to deliver some of the bills toward a first end of the system into the first output receptacle and some of the bills toward a second end of the system into the second output receptacle. The system provides access openings in a front side of the system that are proximate the first and the second output receptacles thereby permitting operator access into the first and the second output receptacles from the front side.

Abstract: According to one embodiment of the present invention, a currency processing device for receiving and processing a stack of currency bills is described. The currency processing device comprises an input receptacle for receiving a stack of bills to be processed, a plurality of output receptacles for receiving bills after the bills have been processed, a transport mechanism for transporting the bills from the input receptacle to the output receptacles, and a discriminating unit for examining the bills. The output receptacles are arranged such that a center of at least one output receptacle is laterally offset from a center of the input receptacle. The discriminating unit includes a detector positioned between the input receptacle and the output receptacles and is adapted to determine the denomination of bills.

Abstract: A currency bill processing system includes a transport mechanism that is configured to transport bills from an input receptacle along a transport path that extends generally horizontally past at least one detector. The transport path transitions generally-vertically upward between a first and a second output receptacle. The transport mechanism is configured to deliver some of the bills toward a first end of the system into the first output receptacle and some of the bills toward a second end of the system into the second output receptacle. The system provides access openings in a front side of the system that are proximate the first and the second output receptacles thereby permitting operator access into the first and the second output receptacles from the front side.

Abstract: A currency bill processing system includes a transport mechanism that is configured to transport bills from an input receptacle along a transport path that extends generally horizontally past at least one detector. The transport path transitions generally-vertically upward between a first and a second output receptacle. The transport mechanism is configured to deliver some of the bills toward a first end of the system into the first output receptacle and some of the bills toward a second end of the system into the second output receptacle. The system provides access openings in a front side of the system that are proximate the first and the second output receptacles thereby permitting operator access into the first and the second output receptacles from the front side.

Abstract: A currency bill processing system includes a transport mechanism that is configured to transport bills from an input receptacle along a transport path that extends generally horizontally past at least one detector. The transport path transitions generally-vertically upward between a first and a second output receptacle. The transport mechanism is configured to deliver some of the bills toward a first end of the system into the first output receptacle and some of the bills toward a second end of the system into the second output receptacle. The system provides access openings in a front side of the system that are proximate the first and the second output receptacles thereby permitting operator access into the first and the second output receptacles from the front side.

Abstract: According to one embodiment of the present invention, a currency processing device for receiving and processing a stack of currency bills is described. The currency processing device comprises an input receptacle for receiving a stack of bills to be processed, a plurality of output receptacles for receiving bills after the bills have been processed, a transport mechanism for transporting the bills from the input receptacle to the output receptacles, and a discriminating unit for examining the bills. The output receptacles are arranged such that a center of at least one output receptacle is laterally offset from a center of the input receptacle. The discriminating unit includes a detector positioned between the input receptacle and the output receptacles and is adapted to determine the denomination of bills.

Abstract: According to one embodiment of the present invention, a currency processing device for receiving and processing a stack of currency bills is described. The currency processing device comprises an input receptacle for receiving a stack of bills to be processed, a plurality of output receptacles for receiving bills after the bills have been processed, a transport mechanism for transporting the bills from the input receptacle to the output receptacles, and a discriminating unit for examining the bills. The output receptacles are arranged such that a center of at least one output receptacle is laterally offset from a center of the input receptacle. The discriminating unit includes a detector positioned between the input receptacle and the output receptacles and is adapted to determine the denomination of bills.

Abstract: According to one embodiment of the present invention, a currency processing device for receiving and processing a stack of currency bills is disclosed. The currency processing device comprises an input receptacle for receiving a stack of bills to be processed, a plurality of output receptacles for receiving bills after the bills have been processed, a transport mechanism for transporting the bills from the input receptacle to the output receptacles, and a discriminating unit for examining the bills. The output receptacles are arranged such that a center of at least one output receptacle is laterally offset from a center of the input receptacle. The discriminating unit includes a detector positioned between the input receptacle and the output receptacles and is adapted to determine the denomination of bills.

Abstract: A currency handling system has a limpness detector. The limpness detector has a single driven crackle roller with an elongated central bulge and two outer bulges, wherein the central bulge is in conforming relation to a flexible belt. Sheet metal guides further facilitate note deformation and sound production.

Abstract: A currency handling system comprising a fitness detector. The fitness detector comprising a thickness detector, a limpness detector, a soil detector or a combination thereof. The thickness detector comprising an upper roller displaceable in a predetermined arc by a note passing between the upper roller and a lower roller. The limpness detector comprising a single driven crackle roller comprising an elongated central bulge and two outer bulges, wherein the central bulge is in conforming relation to a flexible belt. Sheet metal guides further facilitate note deformation and sound production.

Abstract: According to one embodiment of the present invention, a currency processing device for receiving and processing a stack of currency bills is described. The currency processing device comprises an input receptacle for receiving a stack of bills to be processed, a plurality of output receptacles for receiving bills after the bills have been processed, a transport mechanism for transporting the bills from the input receptacle to the output receptacles, and a discriminating unit for examining the bills. The output receptacles are arranged such that a center of at least one output receptacle is laterally offset from a center of the input receptacle. The discriminating unit includes a detector positioned between the input receptacle and the output receptacles and is adapted to determine the denomination of bills.

Abstract: A currency handling system comprising a fitness detector. The fitness detector comprising a thickness detector, a limpness detector, a soil detector or a combination thereof. The thickness detector comprising an upper roller displaceable in a predetermined arc by a note passing between the upper roller and a lower roller. The limpness detector comprising a single driven crackle roller comprising an elongated central bulge and two outer bulges, wherein the central bulge is in conforming relation to a flexible belt. Sheet metal guides further facilitate note deformation and sound production.

Abstract: A currency handling system comprising a fitness detector. The fitness detector comprising a thickness detector, a limpness detector, a soil detector or a combination thereof. The thickness detector comprising an upper roller displaceable in a predetermined arc by a note passing between the upper roller and a lower roller. The limpness detector comprising a single driven crackle roller comprising an elongated central bulge and two outer bulges, wherein the central bulge is in conforming relation to a flexible belt. Sheet metal guides further facilitate note deformation and sound production.

Abstract: A currency handling system comprising a fitness detector. The fitness detector comprising a thickness detector, a limpness detector, a soil detector or a combination thereof. The thickness detector comprising an upper roller displaceable in a predetermined arc by a note passing between the upper roller and a lower roller. The limpness detector comprising a single driven crackle roller comprising an elongated central bulge and two outer bulges, wherein the central bulge is in conforming relation to a flexible belt. Sheet metal guides further facilitate note deformation and sound production.

Abstract: According to one embodiment of the present invention, a currency processing device for receiving and processing a stack of currency bills is disclosed. The currency processing device comprises an input receptacle for receiving a stack of bills to be processed, a plurality of output receptacles for receiving bills after the bills have been processed, a transport mechanism for transporting the bills from the input receptacle to the output receptacles, and a discriminating unit for examining the bills. The output receptacles are arranged such that a center of at least one output receptacle is laterally offset from a center of the input receptacle. The discriminating unit includes a detector positioned between the input receptacle and the output receptacles and is adapted to determine the denomination of bills.