Patents by Inventor Margaret A. Kivinski

Margaret A. Kivinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing gas delivering perfluorocarbon emulsions with non-fluorinated surfactants
    Patent number: 7468191
    Abstract: The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: December 23, 2008
    Assignee: TherOx, Inc.
    Inventors: Li-Chien Hsu, Jeffrey L. Creech, Paul J. Zalesky, Margaret A. Kivinski
  • Perfluorocarbon emulsions with non-fluorinated surfactants
    Patent number: 7357937
    Abstract: A stable FC emulsion is described. The FC emulsion of the present invention comprises a continuous FC immiscible hydrophilic liquid phase and a dispersed phase comprising FC suspended as droplets within the continuous phase. The emulsion further comprises an emulsifying agent and a stabilizing agent. The stabilizing agent of the present invention reduces the ability of the FC droplets to move within the continuous phase. The present invention also provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: April 15, 2008
    Assignee: TherOx, Inc.
    Inventors: Li-Chien Hsu, Jeffrey L. Creech, Paul J. Zalesky, Margaret A. Kivinski
  • Method of Preparing Gas Delivering Perfluorocarbon Emulsions With Non-Fluorinated Surfactants
    Publication number: 20060193878
    Abstract: The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent.
    Type: Application
    Filed: May 8, 2006
    Publication date: August 31, 2006
    Applicant: TherOx, Inc.
    Inventors: Jeffrey Creech, Li-Chien Hsu, Margaret Kivinski, Paul Zalesky
  • Method of Making Perfluorocarbon Emulsions With Non-Fluorinated Surfactants
    Publication number: 20060193799
    Abstract: The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent.
    Type: Application
    Filed: May 8, 2006
    Publication date: August 31, 2006
    Applicant: TherOx, Inc.
    Inventors: Jeffrey Creech, Li-Chien Hsu, Margaret Kivinski, Paul Zalesky
  • Perfluorocarbon emulsions with non-fluorinated surfactants
    Publication number: 20040057906
    Abstract: A stable FC emulsion is described. The FC emulsion of the present invention comprises a continuous FC immiscible hydrophilic liquid phase and a dispersed phase comprising FC suspended as droplets within the continuous phase. The emulsion further comprises an emulsifying agent and a stabilizing agent. The stabilizing agent of the present invention reduces the ability of the FC droplets to move within the continuous phase. The present invention also provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion.
    Type: Application
    Filed: September 24, 2002
    Publication date: March 25, 2004
    Inventors: Li-Chien Hsu, Jeffrey L. Creech, Paul J. Zalesky, Margaret A. Kivinski