Abstract: The present disclosure relates to methods for predicting and improving the outcome of organ transplantation based on features of donor-specific antibodies (DSAs) present in the transplant candidate or recipient. Anti-DSA features include Fc?RIIA binding and Fc glycosylation.

Abstract: Systems and methods for deterring transmission of viruses using neural networks are disclosed. An example method includes detecting in a bodily fluid sample from a subject a set of anti-virus antibody features and generating an input vector that includes data indicative of the anti-virus antibody features of the subject. The method also includes applying the input vector to a trained neural network algorithm that is configured to generate an assigned classification to the subject. The assigned classification is one of a plurality of potential classifications of the neural network algorithm. The method also includes determining whether the pregnant subject is a suitable candidate for therapeutic intervention based on the assigned classification and, responsive to determining that the human subject is suitable, providing the therapeutic intervention to the subject to reduce risk of vertical transmission.

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to 137 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.