Patents by Inventor Margaret Ann Brimble

Margaret Ann Brimble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC ANALOGUES OF NEURAL REGENERATION PEPTIDES
    Publication number: 20150307553
    Abstract: Embodiments of this invention include synthetic compounds (NRP analogues) of peptides termed neural regeneration peptides (NRPs). NRP analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizing ?-turns, acetylation of terminal glycine residues or by cyclization. NRP analogues can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.
    Type: Application
    Filed: May 1, 2015
    Publication date: October 29, 2015
    Inventors: Paul William Richard Harris, Margaret Ann Brimble, Frank Sieg
  • Synthetic analogues of neural regeneration peptides
    Patent number: 9040485
    Abstract: Embodiments of this invention include synthetic compounds (NRP analogues) of peptides termed neural regeneration peptides (NRPs). NRP analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizaing ?-turns, acetylation of terminal glycine residues or by cyclization. NRP analogues can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: May 26, 2015
    Assignee: CURONZ HOLDINGS COMPANY LIMITED
    Inventors: Paul William Richard Harris, Margaret Ann Brimble, Frank Sieg
  • SYNTHETIC ANALOGUES OF NEURAL REGENERATION PEPTIDES
    Publication number: 20130231289
    Abstract: Embodiments of this invention include synthetic compounds (NRP analogues) of peptides termed neural regeneration peptides (NRPs). NRP analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizaing ?-turns, acetylation of terminal glycine residues or by cyclization. NRP analogues can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.
    Type: Application
    Filed: October 15, 2012
    Publication date: September 5, 2013
    Applicant: Curonz Holdings Company Limited
    Inventors: Paul William Richard Harris, Margaret Ann Brimble, Frank Sieg