Patents by Inventor Margaret BASH

Margaret BASH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEISSERIA MENINGITIDIS IMMUNOGENIC COMPOSITIONS
    Publication number: 20230019488
    Abstract: Immunogenic compositions are disclosed that include Neisseria meningitidis microvesicles, such as outer membrane vesicles (OMV) and/or blebs, from PorA?PorB? Neisseria, such as PorA?PorB?ampM? Neisseria meningitidis. These immunogenic compositions are of use to induce an immune response to Neisseria, including Neisseria meningitidis and Neisseria gonorrhea.
    Type: Application
    Filed: September 2, 2022
    Publication date: January 19, 2023
    Applicant: THE U.S.A, as represented by the Secretary, Department of Health and Human Services
    Inventors: Margaret Bash, Kathryn Matthias
  • immunogenic compositions
    Patent number: 11464845
    Abstract: Immunogenic compositions are disclosed that include Neisseria meningitidis microvesicles, such as outer membrane vesicles (OMV) and/or blebs, from PorA?PorB? Neisseria, such as PorA?PorB?RmpM? Neisseria meningitidis. These immunogenic compositions are of use to induce an immune response to Neisseria, including Neisseria meningitidis and Neisseria gonorrhea.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: October 11, 2022
    Assignee: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services
    Inventors: Margaret Bash, Kathryn Matthias
  • BACTERIAL POLYSACCHARIDE-CONJUGATED CARRIER PROTEINS AND USE THEREOF
    Publication number: 20210369833
    Abstract: Immunogenic compositions that include a bacterial capsular polysaccharide conjugated to a carrier protein are described. In some embodiments, the bacterial capsular polysaccharide is a Neisseria meningitidis capsular polysaccharide. The carrier protein includes an N. meningitidis factor H binding protein (fHbp) linked to cholera toxin subunit B (CTB). Administration of the immunogenic compositions elicits an immune response that includes production of meningococcal polysaccharide-specific and fHbP-specific antibodies. Use of the immunogenic compositions as meningococcal vaccines is also described.
    Type: Application
    Filed: August 11, 2021
    Publication date: December 2, 2021
    Applicant: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Gregory A. Price, Che-Hung Robert Lee, Margaret Bash
  • BACTERIAL POLYSACCHARIDE-CONJUGATED CARRIER PROTEINS AND USE THEREOF
    Publication number: 20210154288
    Abstract: Immunogenic compositions that include a bacterial capsular polysaccharide conjugated to a carrier protein are described. In some embodiments, the bacterial capsular polysaccharide is a Neisseria meningitidis capsular polysaccharide. The carrier protein includes an N. meningitidis factor H binding protein (fHbp) linked to cholera toxin subunit B (CTB). Administration of the immunogenic compositions elicits an immune response that includes production of meningococcal polysaccharide-specific and fHbp-specific antibodies. Use of the immunogenic compositions as meningococcal vaccines is also described.
    Type: Application
    Filed: December 18, 2018
    Publication date: May 27, 2021
    Applicant: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Gregory A. Price, Che-Hung Robert Lee, Margaret Bash
  • NEISSERIA MENINGITIDES IMMUNOGENIC COMPOSITIONS
    Publication number: 20200360503
    Abstract: Immunogenic compositions are disclosed that include Neisseria meningitidis microvesicles, such as outer membrane vesicles (OMV) and/or blebs, from PorA?PorB?Neisseria, such as PorA?PorB?RmpM? Neisseria meningitidis. These immunogenic compositions are of use to induce an immune response to Neisseria, including Neisseria meningitidis and Neisseria gonorrhea.
    Type: Application
    Filed: July 20, 2018
    Publication date: November 19, 2020
    Applicants: Health and Human Sevice
    Inventors: Margaret BASH, Kathryn MATTHIAS