Patents by Inventor Margaret HOANG

Margaret HOANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240084361
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: September 21, 2023
    Publication date: March 14, 2024
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Patent number: 11821026
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: March 7, 2023
    Date of Patent: November 21, 2023
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • Publication number: 20230257800
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 7, 2023
    Publication date: August 17, 2023
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • Publication number: 20230220461
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: December 21, 2022
    Publication date: July 13, 2023
    Inventors: Dwayne DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG, Matthew WALSH, Gavin MEREDITH, Mark MCELWAIN, Peter SKENE, Cassandra Burke
  • Patent number: 11549139
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: January 10, 2023
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang, Matthew Walsh, Gavin Meredith, Mark McElwain, Peter Skene, Cassandra Burke
  • Patent number: 11473142
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: October 18, 2022
    Assignee: NanoString Technologies, Inc.
    Inventors: Joseph M. Beechem, Dae Kim, Margaret Hoang, Mark Gregory, Erin Piazza, Denise Zhou
  • Publication number: 20220220555
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Application
    Filed: March 28, 2022
    Publication date: July 14, 2022
    Inventors: Joseph M. BEECHEM, Dae KIM, Margaret HOANG, Mark GREGORY, Erin PIAZZA, Denise ZHOU
  • Publication number: 20220213532
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Patent number: 11377689
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: July 5, 2022
    Assignee: NanoString Technologies, Inc.
    Inventors: Joseph M. Beechem, Dae Kim, Margaret Hoang, Mark Gregory, Erin Piazza, Denise Zhou
  • Patent number: 11279969
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: March 22, 2022
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • Publication number: 20210403998
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Application
    Filed: September 16, 2021
    Publication date: December 30, 2021
    Inventors: Joseph M. BEECHEM, Dae KIM, Margaret HOANG, Mark GREGORY, Erin PIAZZA, Denise ZHOU
  • Publication number: 20210403999
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Application
    Filed: September 16, 2021
    Publication date: December 30, 2021
    Inventors: Joseph M. BEECHEM, Dae KIM, Margaret HOANG, Mark GREGORY, Erin PIAZZA, Denise ZHOU
  • Publication number: 20190390258
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: September 4, 2019
    Publication date: December 26, 2019
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Publication number: 20190345548
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 14, 2019
    Inventors: Dwayne DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG, Matthew WALSH, Gavin MEREDITH, Mark MCELWAIN, Peter Skene, Cassandra Burke
  • Publication number: 20190300946
    Abstract: Bottleneck Sequencing System (BotSeqS) is a next-generation sequencing method that simultaneously quantifies rare somatic point mutations across the mitochondrial and nuclear genomes. BotSeqS combines molecular barcoding with a simple dilution step immediately prior to library amplification. BotSeqS can be used to show age and tissue-dependent accumulations of rare mutations and demonstrate that somatic mutational burden in normal tissues can vary by several orders of magnitude, depending on biologic and environmental factors. BotSeqS has been used to show major differences between the mutational patterns of the mitochondrial and nuclear genomes in normal tissues. Lastly, BotSeqS has shown that the mutation spectra of normal tissues were different from each other, but similar to those of the cancers that arose in them.
    Type: Application
    Filed: January 27, 2017
    Publication date: October 3, 2019
    Inventors: Bert Vogelstein, Kenneth Kinzler, Margaret Hoang, Nickolas Papadopoulos
  • Patent number: 10415080
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: September 17, 2019
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • Publication number: 20190249248
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Application
    Filed: February 11, 2019
    Publication date: August 15, 2019
    Inventors: Joseph M. Beechem, Dae Kim, Margaret Hoang, Mark Gregory, Erin Piazza, Denise Zhou
  • Publication number: 20180142286
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: November 21, 2017
    Publication date: May 24, 2018
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG