Patents by Inventor Margaret Isabel Tyler

Margaret Isabel Tyler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retro-, inverso- and retro-inverso synthetic peptide analogues
    Patent number: 6261569
    Abstract: Synthetic peptide antigen analogues of native peptide antigens with partial or complete retro, inverso or retro-inverso modifications are provided. When administered as an immunogen to an immunocompetent host the synthetic peptide antigen analogues induce the production of antibodies which recognize the native peptide antigen. Uses of these analogues, vaccines and methods of preparing vaccines comprising these antigen analogues, and antibodies generated using these antigen analogues are also provided.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: July 17, 2001
    Assignee: Deakin Research Limited
    Inventors: Alfio Comis, Margaret Isabel Tyler, Peter Fischer
  • Insecticidal toxins derived from funnel web (atrax or hadronyche) spiders
    Patent number: 5959182
    Abstract: The invention relates to insect viruses and plants which express an exogenous polypeptide derived from spiders of the genus Atrax or Hadronyche, which polypeptide is toxic to insects. The polypeptide has a molecular weight of approximately 4000 amu,) containing 36-37 Gino acids, and is capable of forming three intrachain disulfide bridges. Polyiucleotides which encode the polypeptide, insectidoidal compositions and methods of controlling insect infestation of crops are also included.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: September 28, 1999
    Assignee: Zeneca Limited
    Inventors: Ronald Keith Atkinson, Merlin Evelyn Harry Howden, Margaret Isabel Tyler, Edward Joseph Vonarx
  • Insecticidal toxins derived from funnel web (atrax or hadronyche) spiders
    Patent number: 5763568
    Abstract: The invention relates to toxins from venom of Australian funnel web spider species. Eight toxins are specifically exemplified. The toxins have a molecular weight of approximately 4000 amu., containing 36-37 amino acids, and are capable of forming 3 intrachain disulphide bridges. Polynucleotides which encode the toxins, insect viruses and plants which express the toxins and variants of the toxins are also included.
    Type: Grant
    Filed: July 17, 1996
    Date of Patent: June 9, 1998
    Assignee: Zeneca Limited
    Inventors: Ronald Keith Atkinson, Merlin Evelyn Harry Howden, Margaret Isabel Tyler, Edward Joseph Vonarx