Patents by Inventor Margaret J. Sekellick

Margaret J. Sekellick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INFLUENZA VIRUS POPULATIONS, METHODS OF USE AND METHODS OF MAKING THEREOF
    Publication number: 20130156733
    Abstract: Disclosed herein are live attenuated influenza virus compositions for inducing interferon comprising quantified subpopulations of interferon-inducing particles and defective-interfering particles. The live attenuated influenza virus compositions are particularly useful to induce interferon in an individual having or suspected of having a viral infection. Further, by infecting mammalian and avian cells with the live attenuated influenza virus compositions, the compositions optimized for mammalian or avian species can be selected based on the ratio of defective-interfering particles to interferon-inducing particles.
    Type: Application
    Filed: December 20, 2012
    Publication date: June 20, 2013
    Inventors: Philip I. Marcus, John M. Ngunjiri, Margaret J. Sekellick, Chang-Won Lee
  • Chicken interferon gene and novel recombinant DNA
    Patent number: 6716607
    Abstract: A chicken interferon gene coding for the amino acid sequence of SEQ ID NO:1 is disclosed. There is also disclosed a method of producing chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fowl having the chicken interferon gene incorporated therein, and method for delivery of the chicken interferon in the bird, such as by genetic immunization or aerosol. Expression of the gene coding for the amino acid sequence of SEQ ID NO:1 yields functional chicken interferon.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: April 6, 2004
    Assignee: University of Connecticut
    Inventors: Margaret J. Sekellick, Philip I. Marcus, Anthony F. Ferrandino
  • Recombinant avian type i interferon
    Patent number: 6020465
    Abstract: The present invention relates to a chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 2. The present invention also relates to a method of producing chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fowl having the chicken interferon gene incorporated therein, and method for delivery of the chicken interferon in the bird, such as by genetic immunization or aerosol. Expression of the chicken IFN gene yields functional chicken interferon.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: February 1, 2000
    Assignee: University of Connecticut
    Inventors: Margaret J. Sekellick, Philip I. Marcus, Anthony F. Ferrandino
  • Treatment of infection in fowl by oral administration of avian interferon proteins
    Patent number: 5885567
    Abstract: The present invention relates to a chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 1. The present invention also relates to a method of producing biologically active chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fowl having the chicken interferon gene incorporated therein, and method for delivery of the chicken interferon in the bird, such as by genetic immunization or aerosol. Expression of the chicken IFN gene yields functional chicken interferon.
    Type: Grant
    Filed: September 19, 1994
    Date of Patent: March 23, 1999
    Assignee: University of Connecticut
    Inventors: Margaret J. Sekellick, Philip I. Marcus, Anthony F. Ferrandino
  • Nucleic acids encoding avian interferon (IFN) proteins and recombinant methods using them
    Patent number: 5641656
    Abstract: A chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 2 is disclosed. There is also disclosed a method of producing chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes and a method of making a transgenic fowl having the chicken interferon gene incorporated therein.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: June 24, 1997
    Assignee: University of Connecticut
    Inventors: Margaret J. Sekellick, Philip I. Marcus, Anthony F. Ferrandino