Patents by Inventor Margaret James Koziel

Margaret James Koziel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C viral infection treatment using a combination of compounds
    Patent number: 9504705
    Abstract: Described herein is a combination that includes compound (A) of the formula and compound (B) of the formula or a pharmaceutically acceptable salt(s) of the foregoing, for ameliorating and/or treating a hepatitis C viral infection.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: November 29, 2016
    Assignee: Alios BioPharma, Inc.
    Inventors: Julie Krop, Margaret James Koziel, Lawrence M. Blatt, John Fry, Sushmita Mukherjee Chanda
  • HEPATITIS C VIRAL INFECTION TREATMENT USING A COMBINATION OF COMPOUNDS
    Publication number: 20140303113
    Abstract: Described herein is a combination that includes compound (A) and compound (B), or a pharmaceutically acceptable salt of the foregoing, for ameliorating and/or treating a hepatitis C viral infection.
    Type: Application
    Filed: April 3, 2014
    Publication date: October 9, 2014
    Applicants: ALIOS BIOPHARMA, INC., VERTEX PHARMACEUTICALS, INC.
    Inventors: Julie Krop, Margaret James Koziel, Lawrence M. Blatt, John Fry, Sushmita Mukherjee Chanda
  • Therapies for Treating Hepatitis C Virus Infection
    Publication number: 20130273003
    Abstract: The present invention provides a treatment for Hepatitis C virus infection patients of different IL28B gentoypes. The invention therefore provides for the prevention of the clinical sequelae of Hepatitis C viral infections. The present invention also provides a treatment for liver damage and liver inflammation. In one embodiment the invention provides a therapeutic regimen comprising administering to a patient having IL28B genotype CC, CT or TT, VX-222, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 17, 2013
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventor: Margaret James Koziel
  • THERAPIES FOR TREATING HEPATITIS C VIRUS INFECTION
    Publication number: 20130034522
    Abstract: A method of improving the pharmacokinetics of VX-222 in a patient infected with HCV comprises co-administering VX-222 and VX-950 to the patient. A method of treating a patient infected with HCV comprises administering VX-222 and VX-950 to the patient, wherein VX-222 is in an amount of about 20 mg to about 400 mg, and wherein VX-950 is in an amount of about 100 mg to about 1,500 mg. A method of treating a patient infected with HCV comprises administering a therapeutically effective amount of VX-222, wherein VX-222 is administered at an amount of about 20 mg to about 2,000 mg once a day.
    Type: Application
    Filed: July 27, 2012
    Publication date: February 7, 2013
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Maria Rosario, Nathalie Chauret, Shelley George, Tara Lynn Kieffer, Margaret James Koziel, Olivier Nicolas, Louise Proulx