Patents by Inventor Margaret Petty
Margaret Petty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090281147Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: April 29, 2009Publication date: November 12, 2009Applicant: AVENTIS PHARMACEUTICALS INC.Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
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Publication number: 20090270458Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: April 29, 2009Publication date: October 29, 2009Applicant: AVENTIS PHARMACEUTICALS INC.Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
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Publication number: 20090209595Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: April 29, 2009Publication date: August 20, 2009Applicant: AVENTIS PHARMACEUTICALS INC.Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
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Publication number: 20090209594Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: April 29, 2009Publication date: August 20, 2009Applicant: AVENTIS PHARMACEUTICALS INC.Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
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Patent number: 7534803Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: GrantFiled: September 27, 2005Date of Patent: May 19, 2009Assignee: Aventis Pharmaceuticals Inc.Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
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Patent number: 7230015Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: GrantFiled: March 14, 2005Date of Patent: June 12, 2007Assignee: Aventis Pharmaceuticals Inc.Inventors: Craig P Smith, Michel P Rathbone, Margaret Petty, David Rampe
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Patent number: 7179821Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: GrantFiled: March 14, 2005Date of Patent: February 20, 2007Assignee: Aventis Pharmaceuticals Inc.Inventors: Craig P Smith, Michel P Rathbone, Margaret Petty, David Rampe
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Patent number: 7041661Abstract: The invention relates to the use of compound of Formula I in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple sclerosisType: GrantFiled: December 16, 2003Date of Patent: May 9, 2006Assignee: Aventis Pharmaceuticals Inc.Inventors: Bin Zhu, Joseph Wettstein, Margaret A. Petty
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Publication number: 20060025452Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: September 27, 2005Publication date: February 2, 2006Applicant: Avenits Pharmaceuticals Inc.Inventors: Craig Smith, Michel Rathbone, Margaret Petty, David Rampe
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Patent number: 6967210Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: GrantFiled: February 14, 2002Date of Patent: November 22, 2005Assignee: Aventis Pharmaceuticals Inc.Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
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Publication number: 20050234105Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: March 14, 2005Publication date: October 20, 2005Applicant: Aventis Pharmaceuticals Inc.Inventors: Craig Smith, Michel Rathbone, Margaret Petty, David Rampe
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Publication number: 20050159456Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: March 14, 2005Publication date: July 21, 2005Applicant: Aventis Pharmaceuticals Inc.Inventors: Craig Smith, Michel Rathbone, Margaret Petty, David Rampe
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Publication number: 20040157889Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: February 3, 2004Publication date: August 12, 2004Applicant: Aventis Pharmaceuticals Inc.Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
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Publication number: 20040157888Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: February 3, 2004Publication date: August 12, 2004Applicant: Aventis Pharmaceuticals Inc.Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
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Publication number: 20040147504Abstract: The invention relates to the use of compound of Formula I in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple sclerosis.Type: ApplicationFiled: December 16, 2003Publication date: July 29, 2004Applicant: Aventis Pharmaceuticals Inc.Inventors: Bin Zhu, Joseph Wettstein, Margaret A. Petty
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Publication number: 20030105150Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.Type: ApplicationFiled: February 14, 2002Publication date: June 5, 2003Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
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Patent number: 5721233Abstract: Derivatives of 2,3-dihydro-5-benzofuranol, intermediates thereof, and processes useful for their preparation. These compounds are free radical scavengers and are useful in the treatment of conditions capable of being treated by free radical scavengers, such as stroke, nervous system trauma and reperfusion damage.Type: GrantFiled: December 22, 1994Date of Patent: February 24, 1998Assignee: Merrell Pharmaceuticals Inc.Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius
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Patent number: 5545660Abstract: This invention relates to novel hydrazide acyl hydrazinium derivatives of certain 3,4-dihydro-2H-1-benzopyrans of the formula ##STR1## the stereoisomers and mixtures thereof, their inner salts, and the pharmaceutically acceptable salts thereof whereinR is H or C.sub.1-6 alkyl,R.sub.1 is C.sub.1-6 alkyl,R.sub.2 is H or --C(O)R,R.sub.3 and R.sub.4 are independently C.sub.1-6 alkyl;R.sub.5 is C.sub.1-6 alkyl, or ##STR2## with R.sub.8 being H or halogeno, n is zero, 1, 2, or 3 andis a halide, --S(O).sub.3 R.sub.6, or nothing when the inner salt is formedR.sub.6 is H, C.sub.1-6 alkyl, phenyl or 4-methylphenyl,to the intermediates, processes and techniques for their preparation, to their ability to manifest the property of being free radical scavengers, and to their end-use application in the treatment of disease conditions capable of being ameliorated by free radical scavengers.Type: GrantFiled: October 6, 1994Date of Patent: August 13, 1996Assignee: Merrell Pharmaceuticals Inc.Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius
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Patent number: 5510373Abstract: This invention relates to certain hydroxy derivatives of 3,4-dihydro-2,5,7,8-tetraalkyl-2H-1-benzopyran-2-carboxylic acids and the lactones thereof, to the processes and intermediates useful for their preparation and to their use as free radical scavengers useful in the treatment of tissue damage implicated with free oxygen radicals.Type: GrantFiled: October 5, 1994Date of Patent: April 23, 1996Assignee: Merrell Pharmaceuticals Inc.Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius
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Patent number: 5500444Abstract: This invention relates to quaternary ammonium salts of certain 2H-1-benzopyran derivatives, to the intermediates and processes useful for their preparation, to their free-radical scavenger and cellular protective properties and to their end-use application as therapeutic agents.Type: GrantFiled: September 27, 1994Date of Patent: March 19, 1996Assignee: Hoechst Marion Roussel, Inc.Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius