Patents by Inventor Margaret Petty

Margaret Petty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090281147
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: April 29, 2009
    Publication date: November 12, 2009
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
  • Publication number: 20090270458
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: April 29, 2009
    Publication date: October 29, 2009
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
  • Publication number: 20090209595
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: April 29, 2009
    Publication date: August 20, 2009
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
  • Publication number: 20090209594
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: April 29, 2009
    Publication date: August 20, 2009
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Craig P. SMITH, Michel P. RATHBONE, Margaret PETTY, David RAMPE
  • Patent number: 7534803
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: May 19, 2009
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
  • Patent number: 7230015
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: June 12, 2007
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Craig P Smith, Michel P Rathbone, Margaret Petty, David Rampe
  • Patent number: 7179821
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: February 20, 2007
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Craig P Smith, Michel P Rathbone, Margaret Petty, David Rampe
  • Patent number: 7041661
    Abstract: The invention relates to the use of compound of Formula I in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple sclerosis
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: May 9, 2006
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Bin Zhu, Joseph Wettstein, Margaret A. Petty
  • Publication number: 20060025452
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: September 27, 2005
    Publication date: February 2, 2006
    Applicant: Avenits Pharmaceuticals Inc.
    Inventors: Craig Smith, Michel Rathbone, Margaret Petty, David Rampe
  • Patent number: 6967210
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: November 22, 2005
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
  • Publication number: 20050234105
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: March 14, 2005
    Publication date: October 20, 2005
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Craig Smith, Michel Rathbone, Margaret Petty, David Rampe
  • Publication number: 20050159456
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: March 14, 2005
    Publication date: July 21, 2005
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Craig Smith, Michel Rathbone, Margaret Petty, David Rampe
  • Publication number: 20040157889
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: February 3, 2004
    Publication date: August 12, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
  • Publication number: 20040157888
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: February 3, 2004
    Publication date: August 12, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
  • Publication number: 20040147504
    Abstract: The invention relates to the use of compound of Formula I in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple sclerosis.
    Type: Application
    Filed: December 16, 2003
    Publication date: July 29, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Bin Zhu, Joseph Wettstein, Margaret A. Petty
  • Publication number: 20030105150
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Application
    Filed: February 14, 2002
    Publication date: June 5, 2003
    Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
  • Patent number: 5721233
    Abstract: Derivatives of 2,3-dihydro-5-benzofuranol, intermediates thereof, and processes useful for their preparation. These compounds are free radical scavengers and are useful in the treatment of conditions capable of being treated by free radical scavengers, such as stroke, nervous system trauma and reperfusion damage.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: February 24, 1998
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius
  • Patent number: 5545660
    Abstract: This invention relates to novel hydrazide acyl hydrazinium derivatives of certain 3,4-dihydro-2H-1-benzopyrans of the formula ##STR1## the stereoisomers and mixtures thereof, their inner salts, and the pharmaceutically acceptable salts thereof whereinR is H or C.sub.1-6 alkyl,R.sub.1 is C.sub.1-6 alkyl,R.sub.2 is H or --C(O)R,R.sub.3 and R.sub.4 are independently C.sub.1-6 alkyl;R.sub.5 is C.sub.1-6 alkyl, or ##STR2## with R.sub.8 being H or halogeno, n is zero, 1, 2, or 3 andis a halide, --S(O).sub.3 R.sub.6, or nothing when the inner salt is formedR.sub.6 is H, C.sub.1-6 alkyl, phenyl or 4-methylphenyl,to the intermediates, processes and techniques for their preparation, to their ability to manifest the property of being free radical scavengers, and to their end-use application in the treatment of disease conditions capable of being ameliorated by free radical scavengers.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: August 13, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius
  • Patent number: 5510373
    Abstract: This invention relates to certain hydroxy derivatives of 3,4-dihydro-2,5,7,8-tetraalkyl-2H-1-benzopyran-2-carboxylic acids and the lactones thereof, to the processes and intermediates useful for their preparation and to their use as free radical scavengers useful in the treatment of tissue damage implicated with free oxygen radicals.
    Type: Grant
    Filed: October 5, 1994
    Date of Patent: April 23, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius
  • Patent number: 5500444
    Abstract: This invention relates to quaternary ammonium salts of certain 2H-1-benzopyran derivatives, to the intermediates and processes useful for their preparation, to their free-radical scavenger and cellular protective properties and to their end-use application as therapeutic agents.
    Type: Grant
    Filed: September 27, 1994
    Date of Patent: March 19, 1996
    Assignee: Hoechst Marion Roussel, Inc.
    Inventors: J. Martin Grisar, Margaret A. Petty, Frank Bolkenius