Patents by Inventor Margaret S. Sosa

Margaret S. Sosa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholesterol lowering compounds
    Patent number: 5310949
    Abstract: New Zaragozic acids have been isolated from a culture of MF5465. These compounds and their derivatives are active as squalene synthetase inhibitors and are useful in the treatment of hypercholesterolemia.
    Type: Grant
    Filed: September 2, 1992
    Date of Patent: May 10, 1994
    Assignee: Merck & Co., Inc.
    Inventors: Claude Dufresne, Prakash S. Masurekar, Leslie A. Ferrell, Deborah L. Zink, Margaret S. Sosa
  • Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol
    Patent number: 5021341
    Abstract: An antibiotic agent produced by the cultivation of Zalerion arboricola which is a cyclic lipopeptide with very high activity against human pathogens and of very low mammalian toxicity and its production and isolation are described.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: June 4, 1991
    Assignee: Merck & Co., Inc.
    Inventors: Robert A. Giacobbe, Jan S. Tkacz, Prakash S. Masurekar, Louis Kaplan, Margaret S. Sosa